Ultrastable complexes for in vivo use: A bifunctional chelator incorporating a cross-bridged macrocycle

Chemical Communications

Volumn , Issue 19, 2004, Pages 2212-2213

  Lewis, Elizabeth A ^a   Boyle, Ross W ^a   Archibald, Stephen J ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTIN; CHELATING AGENT; COPPER COMPLEX; MACROCYCLIC COMPOUND;

ARTICLE; CHELATION; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONJUGATION; IN VIVO STUDY; SYNTHESIS;

EID: 8144221558     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b406906d     Document Type: Article

References (19)

1. (a) S. Lui and D. S. Edwards, Bioconjugate Chem., 2001, 12, 7;
2. (b) The Chemistry of Contrast Agents in Medicinal Magnetic Resonance Imaging, ed. É. Tóth and A. E. Merbach, Wiley, Chichester 2001.
3. (a) C. F. Meares, A. J. Chumura, M. S. Orton, T. M. Corneillie and P. A. Whetstone, J. Mol. Recognit., 2003, 16, 255;
4. (b) C. J. Anderson, M. A. Green and Y. Fujibayashi in Handbook of Radiopharmaceuticals, ed. M. J. Welch and C. S. Redvanly, Wiley, New York 2003, pp. 401-422.
5. Specific examples include: (a) R. Ruloff, É. Tóth, R. Scopelliti, R. Tripier, H. Handel and A. E. Merbach, Chem. Commun., 2002, 2630; (b) C. J. Mathias, M. J. Welch, M. A. Green, H. Diril, C. F. Meares, R. J. Gropler and S. R. Gergmann, J. Nucl. Med., 1991, 32, 475; (c) G. L. DeNardo, D. L. Kukis, S. Shen, D. A. DeNardo, C. F. Meares and S. J. DeNardo, Clin. Cancer Res., 1999, 5, 533.
6. Specific examples include: (a) R. Ruloff, É. Tóth, R. Scopelliti, R. Tripier, H. Handel and A. E. Merbach, Chem. Commun., 2002, 2630; (b) C. J. Mathias, M. J. Welch, M. A. Green, H. Diril, C. F. Meares, R. J. Gropler and S. R. Gergmann, J. Nucl. Med., 1991, 32, 475; (c) G. L. DeNardo, D. L. Kukis, S. Shen, D. A. DeNardo, C. F. Meares and S. J. DeNardo, Clin. Cancer Res., 1999, 5, 533.
7. Specific examples include: (a) R. Ruloff, É. Tóth, R. Scopelliti, R. Tripier, H. Handel and A. E. Merbach, Chem. Commun., 2002, 2630; (b) C. J. Mathias, M. J. Welch, M. A. Green, H. Diril, C. F. Meares, R. J. Gropler and S. R. Gergmann, J. Nucl. Med., 1991, 32, 475; (c) G. L. DeNardo, D. L. Kukis, S. Shen, D. A. DeNardo, C. F. Meares and S. J. DeNardo, Clin. Cancer Res., 1999, 5, 533.
8. L. A. Bass, M. Wang, M. J. Welch and C. J. Anderson, Bioconjugate Chem., 2000, 11, 527.
9. G. R. Mirick, R. T. O'Donnell, S. J. DeNardo, S. Shen, C. F. Meares and G. L. DeNardo, Nucl. Med. Biol., 1999, 26, 841.
10. E. H. Wong, G. R. Weisman, D. C. Hill, D. P. Reed, M. E. Rogers, J. S. Condon, M. A. Fagan, J. C. Calabrese, K.-C. Lam, I. A. Guzei and A. L. Rheingold, J. Am. Chem. Soc., 2000, 122, 10561.
11. (a) X. Sun, M. Wuest, G. R. Weisman, E. H. Wong, D. P. Reed, C. A. Boswell, R. Motekaitis, A. E. Martell, M. J. Welch and C. J. Anderson, J. Med. Chem., 2002, 45, 469;
12. (b) C. A. Boswell, X. Sun, W. Nui, G. R. Weisman, E. H. Wong, A. L. Rheingold and C. J. Anderson, J. Med. Chem., 2004, 47, 1465.
13. The biological applications of cross-bridged macrocycles have been recognised in a number of patents including: (a) T. J. Hubin and T. J. Meade, Novel Macrocyclic Magnetic Resonance Imaging Contrast Agents, PCT Int. Appl., WO 02/06287 A2, 2002; (b) C. M. Perkins and D. T. Reed, Metal Complexes for Use in Medical and Therapeutic Applications, PCT Int. Appl., WO 02/26748 02, 2000.
14. The biological applications of cross-bridged macrocycles have been recognised in a number of patents including: (a) T. J. Hubin and T. J. Meade, Novel Macrocyclic Magnetic Resonance Imaging Contrast Agents, PCT Int. Appl., WO 02/06287 A2, 2002; (b) C. M. Perkins and D. T. Reed, Metal Complexes for Use in Medical and Therapeutic Applications, PCT Int. Appl., WO 02/26748 02, 2000.
15. E. A. Lewis, C. C. Allan, R. W. Boyle and S. J. Archibald, Tetrahedron Lett., 2004, 45, 3059.
16. For example: (a) T. J. Hubin, J. M. McCormick, S. R. Collinson, N. W. Alcock and D. H. Busch, J. Chem. Soc., Chem. Commun., 1998, 1675; (b) T. J. Hubin, Coord. Chem. Rev., 2003, 247, 27.
17. For example: (a) T. J. Hubin, J. M. McCormick, S. R. Collinson, N. W. Alcock and D. H. Busch, J. Chem. Soc., Chem. Commun., 1998, 1675; (b) T. J. Hubin, Coord. Chem. Rev., 2003, 247, 27.
18. E. A. Bayer and M. Wilchek in Immunoassay, ed. E. P. Diamandis and T. K. Christopoulus, Academic Press, San Diego, CA, 1996, pp. 237-267.
19. G. T. Hermanson, Bioconjugate Techniques, Academic Press, London, 1996, p. 303.