Dahuang Fuzi Decoction ameliorates tubular epithelial apoptosis and renal damage via inhibiting TGF-β1-JNK signaling pathway activation in vivo

Journal of Ethnopharmacology

Volumn 156, Issue , 2014, Pages 115-124

  Tu, Yue ^a   Sun, Wei ^a   Wan, Yi Gang ^b   Gao, Kun ^c   Liu, Hong ^a   Yu, Bing Yin ^a   Hu, Hao ^a   Huang, Yan Ru ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Adenine induced renal failure; c JunNH2 terminal kinase; Dahuang Fuzi Decoction; Transforming growth factor 1; Tubular epithelial apoptosis

Indexed keywords

ADENINE; ALLOPURINOL; CASPASE 3; CHINESE DRUG; CREATININE; DAHUANG FUZI; HERBACEOUS AGENT; N ACETYL BETA GLUCOSAMINIDASE; PROTEIN BAX; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; URIC ACID; URINARY TRACT AGENT; ACETYLGLUCOSAMINIDASE; FUZI; PLANT EXTRACT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVATION; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; IN VIVO STUDY; KIDNEY INJURY; KIDNEY TUBULE CELL; MALE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; PROTEINURIA; RAT; SIGNAL TRANSDUCTION; UREA NITROGEN BLOOD LEVEL; URIC ACID BLOOD LEVEL; WESTERN BLOTTING; ACUTE KIDNEY INJURY; ANIMAL; DISEASE MODEL; DRUG EFFECTS; KIDNEY; KIDNEY TUBULE; METABOLISM;

ACETYLGLUCOSAMINIDASE; ACUTE KIDNEY INJURY; ALLOPURINOL; ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; KIDNEY; KIDNEY TUBULES; MALE; MAP KINASE SIGNALING SYSTEM; MEDICINE, CHINESE TRADITIONAL; PLANT EXTRACTS; RATS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84907209607     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.08.035     Document Type: Article

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