Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer

International Journal of Oncology

Volumn 45, Issue 5, 2014, Pages 2101-2107

  Yeh, Chia Ming ^a   Shay, Jacqueline ^a   Zeng, Ting Chuan ^a   Chou, Jian Liang ^a   Huang, Tim H M ^b   Lai, Hung Cheng ^c,d,e   Chan, Michael W Y ^a  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

ARNTL; Circadian clock; Epigenetic modifications; Ovarian cancer; Tumor suppressor

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANTINEOPLASTIC AGENT; BISULFITE; CISPLATIN; DNA METHYLTRANSFERASE INHIBITOR; GSK 126; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; ARNTL PROTEIN, HUMAN; HISTONE;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CELL GROWTH; CHEMOSENSITIVITY; CIRCADIAN RHYTHM; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; FEMALE; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE SILENCING; HISTONE MODIFICATION; HUMAN; MICROARRAY ANALYSIS; ONCOGENE C MYC; OVARIAN CANCER CELL LINE; OVARY CANCER; PROMOTER REGION; RESTRICTION MAPPING; TREATMENT OUTCOME; TUMOR SUPPRESSOR GENE; ANTAGONISTS AND INHIBITORS; EPIGENETIC REPRESSION; GENE EXPRESSION REGULATION; GENETICS; OVARY TUMOR; PATHOLOGY;

ARNTL TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CPG ISLANDS; DNA METHYLATION; EPIGENETIC REPRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HISTONES; HUMANS; OVARIAN NEOPLASMS; PROMOTER REGIONS, GENETIC;

EID: 84907197942     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2014.2627     Document Type: Article

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