A novel mouse model of soft-tissue infection using bioluminescence imaging allows noninvasive, real-time monitoring of bacterial growth

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Yoshioka, Kenji ^a   Ishii, Ken ^a,c   Kuramoto, Tetsuya ^a   Nagai, Shigenori ^a,d,e   Funao, Haruki ^a   Ishihama, Hiroko ^a   Shiono, Yuta ^a   Sasaki, Aya ^a   Aizawa, Mamoru ^b,c   Okada, Yasunori ^a   Koyasu, Shigeo ^a,f   Toyama, Yoshiaki ^a   Matsumoto, Morio ^a  

^a KEIO UNIVERSITY   (Japan)

^b MEIJI UNIVERSITY   (Japan)

^c KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^f Institute of Physical and Chemical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6;

ABSCESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM EXAMINATION; BIOLOGICAL MONITORING; BIOLUMINESCENCE IMAGING; CONTROLLED STUDY; FLUORESCENCE IMAGING; HISTOPATHOLOGY; IMAGING SYSTEM; IN VIVO STUDY; INOCULATION; LIGHT INTENSITY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MOUSE; MUSCLE NECROSIS; MYOSITIS; NEUTROPHIL CHEMOTAXIS; NON INVASIVE PROCEDURE; NONHUMAN; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; SEROLOGY; SKELETAL MUSCLE; SOFT TISSUE INFECTION; SUPERFICIAL GLUTEUS MUSCLE; ANIMAL; BAGG ALBINO MOUSE; DIAGNOSTIC IMAGING; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; LUMINESCENCE; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS);

ANIMALS; DIAGNOSTIC IMAGING; DISEASE MODELS, ANIMAL; LUMINESCENT MEASUREMENTS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICE; MICE, INBRED BALB C; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84907196561     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106367     Document Type: Article

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