Renal PKC-ε deficiency attenuates acute kidney injury and ischemic allograft injury via TNF-[1]-dependent inhibition of apoptosis and inflammation

American Journal of Physiology - Renal Physiology

Volumn 307, Issue 6, 2014, Pages F718-F726

  Rong, Song ^a,c   Hueper, Katja ^a   Kirsch, Torsten ^a   Greite, Robert ^a   Klemann, Christian ^a   Menge, Michael ^d   Meier, Matthias ^a   Menne, Jan ^a,b   Leitges, Michael ^a,e   Susnik, Nathan ^a   Meier, Martin ^a   Haller, Hermann ^a   Shushakova, Nelli ^a,b   Gueler, Faikah ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Phenos GmbH   (Germany)

^c ZUNYI MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF ALBERTA   (Canada)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

Allograft rejection; Functional magnetic resonance imaging; Inflammation; Ischemia reperfusion injury; Protein kinase C ; Transplantation; Tumor necrosis factor

Indexed keywords

CASPASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN KINASE C EPSILON; TUMOR NECROSIS FACTOR ALPHA; ICAM1 PROTEIN, MOUSE; PRKCE PROTEIN, MOUSE; REACTIVE OXYGEN METABOLITE;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME INHIBITION; EPITHELIUM CELL; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAFT RECIPIENT; GRAFT SURVIVAL; INFLAMMATION; INFLAMMATORY CELL; ISCHEMIC ALLOGRAFT INJURY; KIDNEY ALLOGRAFT; KIDNEY ALLOGRAFT REJECTION; KIDNEY CELL; KIDNEY FUNCTION; KIDNEY GRAFT; KIDNEY ISCHEMIA; KIDNEY PERFUSION; KIDNEY TRANSPLANTATION; LEUKOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION INJURY; SEVERE RENAL IMPAIRMENT; SIGNAL TRANSDUCTION; SURVIVAL RATE; UPREGULATION; WILD TYPE; ALLOGRAFT; ANIMAL; BAGG ALBINO MOUSE; ENZYMOLOGY; KIDNEY FUNCTION TEST; METABOLISM;

ACUTE KIDNEY INJURY; ALLOGRAFTS; ANIMALS; APOPTOSIS; GRAFT SURVIVAL; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY FUNCTION TESTS; KIDNEY TRANSPLANTATION; MALE; MICE; MICE, INBRED BALB C; PROTEIN KINASE C-EPSILON; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84907143773     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00372.2013     Document Type: Article

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