Progressive changes in hippocampal resting-state connectivity across cognitive impairment: A cross-sectional study from normal to alzheimer disease

Alzheimer Disease and Associated Disorders

Volumn 28, Issue 3, 2014, Pages 239-246

  Sohn, William Seunghyun ^a   Yoo, Kwangsun ^a   Na, Duk L ^b   Jeong, Yong ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Alzheimer disease; amnestic mild cognitive impairment; fMRI; hippocampal connectivity; resting state

Indexed keywords

AGED; ALZHEIMER DISEASE; ANTERIOR CINGULATE; ARTICLE; ATTENTION; BOLD SIGNAL; CLINICAL DEMENTIA RATING; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; ECHO PLANAR IMAGING; EXECUTIVE FUNCTION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; MAJOR CLINICAL STUDY; MALE; MAMMILLARY BODY; MEMORY; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; NEUROIMAGING; NEUROLOGIC EXAMINATION; PARAHIPPOCAMPAL GYRUS; PARIETAL LOBE; POSTERIOR CINGULATE; PRIORITY JOURNAL; THALAMUS; COMPUTER ASSISTED DIAGNOSIS; DISEASE COURSE; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; REST; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; FEMALE; HIPPOCAMPUS; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MILD COGNITIVE IMPAIRMENT; NEURAL PATHWAYS; REST;

EID: 84907140866     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/WAD.0000000000000027     Document Type: Article

References (58)

1. Cummings JL. Alzheimer's disease. N Engl J Med. 2004;351:56-67.
2. Rogers SL, Farlow MR, Doody RS, et al. A 24-week, doubleblind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Donepezil Study Group. Neurology. 1998;50:136-145.
3. Tariot PN, Solomon PR, Morris JC, et al. A 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group. Neurology. 2000; 54:2269-2276.
4. Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: Clinical characterization and outcome. Arch Neurol. 1999;56:303-308.
5. Dubois B. "Prodromal Alzheimer's disease": A more useful concept than mild cognitive impairment? Curr Opin Neurol. 2000;13:367-369.
6. Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci. 2007;8:700-711.
7. Raichle ME. The restless brain. Brain Connect. 2011;1:3-12.
8. Sperling RA, Laviolette PS, O'Keefe K, et al. Amyloid deposition is associated with impaired default network function in older persons without dementia. Neuron. 2009;63:178-188.
9. Rodrigue KM, Kennedy KM, Park DC. Beta-amyloid deposition and the aging brain. Neuropsychol Rev. 2009;19:436-450.
10. Bondareff W, Mountjoy CQ, Roth M, et al. Neurofibrillary degeneration and neuronal loss in Alzheimer's disease. Neurobiol Aging. 1989;10:709-715.
11. Greicius MD, Srivastava G, Reiss AL, et al. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functionalMRI. Proc Natl Acad Sci USA. 2004;101:4637-4642.
12. Koch W, Teipel S, Mueller S, et al. Diagnostic power of default mode network resting state fMRI in the detection of Alzheimer's disease. Neurobiol Aging. 2012;33:466-478.
13. Rombouts SA, Barkhof F, Goekoop R, et al. Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: An fMRI study. Hum Brain Mapp. 2005;26:231-239.
14. Binnewijzend MA, Schoonheim MM, Sanz-Arigita E, et al. Resting-state fMRI changes in Alzheimer's disease and mild cognitive impairment. Neurobiol Aging. 2012;33:2018-2028.
15. Damoiseaux JS, Prater KE, Miller BL, et al. Functional connectivity tracks clinical deterioration in Alzheimer's disease. Neurobiol Aging. 2012;33:828e19-828e30.
16. Buckner RL, Snyder AZ, Shannon BJ, et al. Molecular, structural, and functional characterization of Alzheimer's disease: Evidence for a relationship between default activity, amyloid, and memory. J Neurosci. 2005;25:7709-7717.
17. Bero AW, Yan P, Roh JH, et al. Neuronal activity regulates the regional vulnerability to amyloid-beta deposition. Nat Neurosci. 2011;14:750-756.
18. Drzezga A, Becker JA, Van Dijk KR, et al. Neuronal dysfunction and disconnection of cortical hubs in nondemented subjects with elevated amyloid burden. Brain. 2011;134:1635-1646.
19. Choo IH, Lee DY, Youn JC, et al. Topographic patterns of brain functional impairment progression according to clinical severity staging in 116 Alzheimer disease patients: FDGPET study. Alzheimer Dis Assoc Disord. 2007;21:77-84.
20. Brier MR, Thomas JB, Snyder AZ, et al. Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression. J Neurosci. 2012;32:8890-8899.
21. Bird CM, Burgess N. The hippocampus and memory: Insights from spatial processing. Nat Rev Neurosci. 2008;9:182-194.
22. Pennanen C, Kivipelto M, Tuomainen S, et al. Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. Neurobiol Aging. 2004;25:303-310.
23. Devanand DP, Pradhaban G, Liu X, et al. Hippocampal and entorhinal atrophy in mild cognitive impairment: Prediction of Alzheimer disease. Neurology. 2007;68:828-836.
24. Bracco L, Piccini C, Manfredi G, et al. Magnetic resonance measures in Alzheimer disease: Their utility in early diagnosis and evaluating disease progression. Alzheimer Dis Assoc Dis. 1999;13:157-164.
25. Marigliano V, Gualdi G, Servello A, et al. Olfactory deficit and hippocampal volume loss for early diagnosis of Alzheimer disease: A pilot study. Alzheimer Dis Assoc Dis. 2013. [Epub ahead of print].
26. Johnson SC, Schmitz TW, Moritz CH, et al. Activation of brain regions vulnerable to Alzheimer's disease: The effect of mild cognitive impairment. Neurobiol Aging. 2006;27:1604-1612.
27. Remy F, Mirrashed F, Campbell B, et al. Verbal episodic memory impairment in Alzheimer's disease: A combined structural and functional MRI study. NeuroImage. 2005;25:253-266.
28. Zhou Y, Dougherty JH Jr, Hubner KF, et al. Abnormal connectivity in the posterior cingulate and hippocampus in early Alzheimer's disease and mild cognitive impairment. Alzheimers Dement. 2008;4:265-270.
29. Wang L, Zang Y, He Y, et al. Changes in hippocampal connectivity in the early stages of Alzheimer's disease: Evidence from resting state fMRI. NeuroImage. 2006;31:496-504.
30. Bai F, Xie C, Watson DR, et al. Aberrant hippocampal subregion networks associated with the classifications of aMCI subjects: A longitudinal resting-state study. PloS One. 2011;6:e29288.
31. Ahn HJ, Chin J, Park A, et al. Seoul Neuropsychological Screening Battery-dementia version (SNSB-D): A useful tool for assessing and monitoring cognitive impairments in dementia patients. J Korean Med Sci. 2010;25:1071-1076.
32. Faul F, Erdfelder E, Lang AG, et al. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39:175-191.
33. Park HK, Na DL, Han SH, et al. Clinical characteristics of a nationwide hospital-based registry of mild-to-moderate Alzheimer's disease patients in Korea: A CREDOS (Clinical Research Center for Dementia of South Korea) study. J Korean Med Sci. 2011;26:1219-1226.
34. Petersen RC, Smith GE, Waring SC, et al. Aging, memory, and mild cognitive impairment. Int Psychogeriatr. 1997;9(suppl 1): 65-69.
35. Morris JC. The clinical dementia rating (CDR): Current version and scoring rules. Neurology. 1993;43:2412-2414.
36. Jenkinson M, Smith S. A global optimisation method for robust affine registration of brain images. Med Image Anal. 2001;5:143-156.
37. Jenkinson M, Bannister P, Brady M, et al. Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage. 2002;17:825-841.
38. Aggleton JP, Brown MW. Episodic memory, amnesia, and the hippocampal-anterior thalamic axis. Behav Brain Sci. 1999;22:425-444; discussion 44-89.
39. Uncapher MR, Rugg MD. Encoding and the durability of episodic memory: A functional magnetic resonance imaging study. J Neurosci. 2005;25:7260-7267.
40. Vertes RP, Albo Z, Viana Di Prisco G. Theta-rhythmically firing neurons in the anterior thalamus: Implications for mnemonic functions of Papez's circuit. Neuroscience. 2001;104:619-625.
41. Zhang HY, Wang SJ, Liu B, et al. Resting brain connectivity: Changes during the progress of Alzheimer disease. Radiology. 2010;256:598-606.
42. Buckner RL. Memory and executive function in aging and AD: Multiple factors that cause decline and reserve factors that compensate. Neuron. 2004;44:195-208.
43. Logan JM, Sanders AL, Snyder AZ, et al. Under-recruitment and nonselective recruitment: Dissociable neural mechanisms associated with aging. Neuron. 2002;33:827-840.
44. Sheline YI, Raichle ME, Snyder AZ, et al. Amyloid plaques disrupt resting state default mode network connectivity in cognitively normal elderly. Biol Psychiatry. 2010;67:584-587.
45. Sambataro F, Murty VP, Callicott JH, et al. Age-related alterations in default mode network: Impact on working memory performance. Neurobiol Aging. 2010;31:839-852.
46. Wirth M, Jann K, Dierks T, et al. Semantic memory involvement in the default mode network: A functional neuroimaging study using independent component analysis. NeuroImage. 2011;54:3057-3066.
47. Cole MW, Pathak S, Schneider W. Identifying the brain's most globally connected regions. NeuroImage. 2010;49:3132-3148.
48. Zhang HY, Wang SJ, Xing J, et al. Detection of PCC functional connectivity characteristics in resting-state fMRI in mild Alzheimer's disease. Behav Brain Res. 2009;197:103-108.
49. Wu X, Li R, Fleisher AS, et al. Altered default mode network connectivity in Alzheimer's disease-a resting functional MRI and Bayesian network study. Hum Brain Mapp. 2011;32:1868-1881.
50. Agosta F, Pievani M, Geroldi C, et al. Resting state fMRI in Alzheimer's disease: Beyond the default mode network. Neurobiol Aging. 2012;33:1564-1578.
51. Scheff SW, Price DA, Schmitt FA, et al. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology. 2007;68:1501-1508.
52. Woodard JL, Grafton ST, Votaw JR, et al. Compensatory recruitment of neural resources during overt rehearsal of word lists in Alzheimer's disease. Neuropsychology. 1998;12:491-504.
53. Grady CL, McIntosh AR, Beig S, et al. Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J Neurosci. 2003;23:986-993.
54. Coricelli G, Nagel R. Neural correlates of depth of strategic reasoning in medial prefrontal cortex. Proc Natl Acad Sci USA. 2009;106:9163-9168.
55. Braak H, Braak E. Neuropathological stageing of Alzheimerrelated changes. Acta Neuropathol. 1991;82:239-259.
56. Allen N, Robinson AC, Snowden J, et al. Patterns of cerebral amyloid angiopathy define histopathological phenotypes in Alzheimer's disease. Neuropathol Appl Neurobiol. 2014;40:136-148.
57. Loewenstein DA, Barker WW, Chang JY, et al. Predominant left hemisphere metabolic dysfunction in dementia. Arch Neurol. 1989;46:146-152.
58. Raji CA, Becker JT, Tsopelas ND, et al. Characterizing regional correlation, laterality and symmetry of amyloid deposition in mild cognitive impairment and Alzheimer's disease with Pittsburgh compound B. J Neurosci Methods. 2008;172:277-282.