Defective anti-polysaccharide response and splenic marginal zone disorganization in ALPS patients

Blood

Volumn 124, Issue 10, 2014, Pages 1597-1609

  Neven, Bénédicte ^a,b   Bruneau, Julie ^a,c   Stolzenberg, Marie Claude ^b   Meyts, Isabelle ^d   Magerus Chatinet, Aude ^b   Moens, Leen ^d   Lanzarotti, Nina ^b   Weller, Sandra ^b   Amiranoff, Denise ^a   Florkin, Benoit ^e   Bader Meunier, Brigitte ^a,b   Leverger, Guy ^f   Ferster, Alice ^g   Chantrain, Christophe ^h   Blanche, Stéphane ^a   Picard, Capucine ^a,i,j   Molina, Thierry Jo ^a   Brousse, Nicole ^a   Durandy, Anne ^b   Rizzi, Marta ^k   Bossuyt, Xavier ^b   Fischer, Alain ^a,b,l   Rieux Laucat, Frederic ^b   more..

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e Centre Hospitalier Regional de La Citadelle   (Belgium)

^f ARMAND TROUSSEAU HOSPITAL   (France)

^g HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

^h Centre Hospitalier Chretien   (Belgium)

ⁱ ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^j UNIVERSITÉ PARIS DESCARTES   (France)

^k UNIVERSITY OF FREIBURG   (Germany)

^l Centre de Recherche Interdisciplinaire en Biologie   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; POLYSACCHARIDE; LIPOPOLYSACCHARIDE;

ADOLESCENT; ADULT; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; B LYMPHOCYTE; BACTERIAL INFECTION; CELLULAR DISTRIBUTION; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; FOLLOW UP; HEMATOLOGICAL PARAMETERS; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; INFANT; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MEMORY CELL; OBSERVATIONAL STUDY; PERSONAL EXPERIENCE; SPLENECTOMY; SPLENIC MARGINAL ZONE; STREPTOCOCCUS PNEUMONIAE; STROMA CELL; ANIMAL; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MOUSE; NEWBORN; PATHOLOGY; PRESCHOOL CHILD; SPLEEN; STATISTICS; STREPTOCOCCUS INFECTION; TRANSGENIC MOUSE; YOUNG ADULT;

ADOLESCENT; ADULT; ANIMALS; ANTIBODY FORMATION; AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; INFANT, NEWBORN; LIPOPOLYSACCHARIDES; MICE; MICE, TRANSGENIC; SPLEEN; SPLENECTOMY; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; YOUNG ADULT;

EID: 84907059410     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-02-553834     Document Type: Article

References (35)

1. Rieux-Laucat F, Le Deist F, Hivroz C, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science. 1995;268(5215):1347-1349.
2. Fisher GH, Rosenberg FJ, Straus SE, et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell. 1995;81(6):935-946.
3. Holzelova E, Vonarbourg C, Stolzenberg MC, et al. Autoimmune lymphoproliferative syndrome with somatic Fas mutations. N Engl J Med. 2004;351(14):1409-1418.
4. Lim MS, Straus SE, Dale JK, et al. Pathological findings in human autoimmune lymphoproliferative syndrome. Am J Pathol. 1998;153(5):1541-1550.
5. Neven B, Magerus-Chatinet A, Florkin B, et al. A survey of 90 patients with autoimmune lymphoproliferative syndrome related to TNFRSF6 mutation. Blood. 2011;118(18):4798-4807.
6. Canale VC, Smith CH. Chronic lymphadenopathy simulating malignant lymphoma. J Pediatr. 1967;70(6):891-899.
7. Sneller MC, Wang J, Dale JK, et al. Clincal, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis. Blood. 1997;89(4):1341-1348.
8. Rao VK, Oliveira JB. How I treat autoimmune lymphoproliferative syndrome. Blood. 2011;118(22):5741-5751.
9. Rensing-Ehl A, Warnatz K, Fuchs S, et al. Clinical and immunological overlap between autoimmune lymphoproliferative syndrome and common variable immunodeficiency. Clin Immunol. 2010;137(3):357-365.
10. Di Sabatino A, Carsetti R, Corazza GR. Post-splenectomy and hyposplenic states. Lancet. 2011;378(9785):86-97.
11. King H, Shumacker HB Jr. Splenic studies. I. Susceptibility to infection after splenectomy performed in infancy. Ann Surg. 1952;136(2):239-242.
12. Cullingford GL, Watkins DN, Watts AD, Mallon DF. Severe late postsplenectomy infection. Br J Surg. 1991;78(6):716-721.
13. Bisharat N, Omari H, Lavi I, Raz R. Risk of infection and death among post-splenectomy patients. J Infect. 2001;43(3):182-186.
14. Ejstrud P, Kristensen B, Hansen JB, Madsen KM, Schønheyder HC, Sørensen HT. Risk and patterns of bacteraemia after splenectomy: a population-based study. Scand J Infect Dis. 2000;32(5):521-525.
15. Mebius RE, Kraal G. Structure and function of the spleen. Nat Rev Immunol. 2005;5(8):606-616.
16. Steiniger B, Barth P, Hellinger A. The perifollicular and marginal zones of the human splenic white pulp: do fibroblasts guide lymphocyte immigration? Am J Pathol. 2001;159(2):501-512.
17. Steiniger B, Timphus EM, Barth PJ. The splenic marginal zone in humans and rodents: an enigmatic compartment and its inhabitants. Histochem Cell Biol. 2006;126(6):641-648.
18. Kruetzmann S, Rosado MM, Weber H, et al. Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleen. J Exp Med. 2003;197(7):939-945.
19. Weller S, Braun MC, Tan BK, et al. Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire. Blood. 2004;104(12):3647-3654.
20. Carsetti R, Pantosti A, Quinti I. Impairment of the antipolysaccharide response in splenectomized patients is due to the lack of immunoglobulin M memory B cells. J Infect Dis. 2006;193(8):1189-1190.
21. Moens L, Wuyts M, Meyts I, De Boeck K, Bossuyt X. Human memory B lymphocyte subsets fulfill distinct roles in the anti-polysaccharide and anti-protein immune response. J Immunol. 2008;181(8):5306-5312.
22. Wasserstrom H, Bussel J, Lim LC, Cunningham-Rundles C. Memory B cells and pneumococcal antibody after splenectomy. J Immunol. 2008;181(5):3684-3689.
23. Weill JC, Weller S, Reynaud CA. Human marginal zone B cells. Annu Rev Immunol. 2009;27:267-285.
24. Oliveira JB, Bleesing JJ, Dianzani U, et al. Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop. Blood. 2010;116(14):e35-e40.
25. Magerus-Chatinet A, Stolzenberg MC, Loffredo MS, et al. FAS-L, IL-10, and double-negative CD4- CD8- TCR alpha/beta+ T cells are reliable markers of autoimmune lymphoproliferative syndrome (ALPS) associated with FAS loss of function. Blood. 2009;113(13):3027-3030.
26. Rensing-Ehl A, Janda A, Lorenz MR, et al. Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia. Haematologica. 2013;98(12):1948-1955.
27. Overturf GD. American Academy of Pediatrics. Committee on Infectious Diseases. Technical report: prevention of pneumococcal infections, including the use of pneumococcal conjugate and polysaccharide vaccines and antibiotic prophylaxis. Pediatrics. 2000;106(2):367-376.
28. Varon E. Epidemiology of Streptococcus pneumoniae. Med Mal Infect. 2012;42(8):361-365.
29. Waldman JD, Rosenthal A, Smith AL, Shurin S, Nadas AS. Sepsis and congenital asplenia. J Pediatr. 1977;90(4):555-559.
30. Mullen CA, Anderson KD, Blaese RM. Splenectomy and/or bone marrow transplantation in the management of the Wiskott-Aldrich syndrome: long-term follow-up of 62 cases. Blood. 1993;82(10):2961-2966.
31. Vermi W, Blanzuoli L, Kraus MD, et al. The spleen in the Wiskott-Aldrich syndrome: histopathologic abnormalities of the white pulp correlate with the clinical phenotype of the disease. Am J Surg Pathol. 1999;23(2):182-191.
32. Teachey DT. New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome. Curr Opin Pediatr. 2012;24(1):1-8.
33. Nezelof C, Maupas C, Griscelli C. The disappearance of germinal centers in chronic lymphadeno-hepato-splenomegaly syndrome in childhood: report of three cases. Pediatr Pathol. 1989;9(1):57-71.
34. Jacobson BA, Panka DJ, Nguyen KA, Erikson J, Abbas AK, Marshak-Rothstein A. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity. 1995;3(4):509-519.
35. Usui T, Yoshioka H, Ko K, et al. Age associated changes in the distribution of lpr gene-induced B220-positive T cells in lymphoid organs of MRL/Mp-lpr/lpr mice using dual exposure microphotographs of double immunofluorescence staining. Biotech Histochem. 1996;71(4):182-189.