-
2
-
-
15644377395
-
Immunological heterogeneity in type i diabetes: Presence of distinct autoAb patterns in patients with acute onset and slowly progressive disease
-
Seissler J, de Sonnaville JJ, Morgenthaler NG, Steinbrenner H, Glawe D, Khoo-Morgenthaler UY, et al. Immunological heterogeneity in type I diabetes: presence of distinct autoAb patterns in patients with acute onset and slowly progressive disease. Diabetologia 1998; 41: 891-897.
-
(1998)
Diabetologia
, vol.41
, pp. 891-897
-
-
Seissler, J.1
De Sonnaville, J.J.2
Morgenthaler, N.G.3
Steinbrenner, H.4
Glawe, D.5
Khoo-Morgenthaler, U.Y.6
-
3
-
-
0020825558
-
Type i diabetes mellitus in monozygotic twins: Chronic progressive beta cell dysfunction
-
Srikanta S, Ganda OP, Jackson RA, Gleason RE, Kaldany A, Garovoy MR, et al. Type I diabetes mellitus in monozygotic twins: chronic progressive beta cell dysfunction. Ann Intern Med 1983; 99: 320-326.
-
(1983)
Ann Intern Med
, vol.99
, pp. 320-326
-
-
Srikanta, S.1
Ganda, O.P.2
Jackson, R.A.3
Gleason, R.E.4
Kaldany, A.5
Garovoy, M.R.6
-
4
-
-
16244396427
-
The Stages of Type 1A Diabetes 2005
-
Gianani R and Eisenbarth GS. The stages of type 1A diabetes: 2005. Immunol Rev 2005; 204: 232-249.
-
(2005)
Immunol Rev
, vol.204
, pp. 232-249
-
-
Gianani, R.1
Eisenbarth, G.S.2
-
5
-
-
0035076588
-
The role of viruses in Type i diabetes: Two distinct cellular and molecular pathogenic mechanisms of virusinduced diabetes in animals
-
Jun HS and Yoon JW. The role of viruses in Type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virusinduced diabetes in animals. Diabetologia 2001; 44: 271-285.
-
(2001)
Diabetologia
, vol.44
, pp. 271-285
-
-
Jun, H.S.1
Yoon, J.W.2
-
6
-
-
0037217057
-
A new took at viruses in type 1 diabetes
-
Jun HS and Yoon JW. A new took at viruses in type 1 diabetes. Diabetes Metab Res Rev 2003; 19: 8-31.
-
(2003)
Diabetes Metab Res Rev
, vol.19
, pp. 8-31
-
-
Jun, H.S.1
Yoon, J.W.2
-
8
-
-
24144449831
-
LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation
-
Mordes JP, Guberski DL, Leif JH, Woda BA, Flanagan JF, Greiner DL, et al. LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. Diabetes 2005; 54: 2727-2733.
-
(2005)
Diabetes
, vol.54
, pp. 2727-2733
-
-
Mordes, J.P.1
Guberski, D.L.2
Leif, J.H.3
Woda, B.A.4
Flanagan, J.F.5
Greiner, D.L.6
-
9
-
-
63249107452
-
Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms
-
Zipris D. Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms. Clin Immunol 2009; 131: 11-23.
-
(2009)
Clin Immunol
, vol.131
, pp. 11-23
-
-
Zipris, D.1
-
10
-
-
0029665016
-
Kilham rat triggers T-cell-dependent autoimmune diabetes in multiple strains of rat
-
Ellerman KE, Richards CA, Guberski DL, Shek WR and Like AA. Kilham rat triggers T-cell-dependent autoimmune diabetes in multiple strains of rat. Diabetes 1996; 45: 557-562.
-
(1996)
Diabetes
, vol.45
, pp. 557-562
-
-
Ellerman, K.E.1
Richards, C.A.2
Guberski, D.L.3
Shek, W.R.4
Like, A.A.5
-
11
-
-
55249122121
-
Innate immunity and its role in type 1 diabetes
-
Zipris D. Innate immunity and its role in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes 2008; 15: 326-331.
-
(2008)
Curr Opin Endocrinol Diabetes Obes
, vol.15
, pp. 326-331
-
-
Zipris, D.1
-
12
-
-
77953953485
-
Toll-like receptors and type 1 diabetes
-
Zipris D. Toll-like receptors and type 1 diabetes. Adv Exp Med Biol 2010; 654: 585-610.
-
(2010)
Adv Exp Med Biol
, vol.654
, pp. 585-610
-
-
Zipris, D.1
-
13
-
-
77951880662
-
Brief dexamethasone treatment during acute infection prevents virus-induced autoimmune diabetes
-
Londono P, Komura A, Hara N and Zipris D. Brief dexamethasone treatment during acute infection prevents virus-induced autoimmune diabetes. Clin Immunol 2010; 135: 401-411.
-
(2010)
Clin Immunol
, vol.135
, pp. 401-411
-
-
Londono, P.1
Komura, A.2
Hara, N.3
Zipris, D.4
-
14
-
-
84867286012
-
Prevention of virus-induced type 1 diabetes with antibiotic therapy
-
Hara N, Alkanani AK, Ir D, Robertson CE, Wagner BD, Frank DN, et al. Prevention of virus-induced type 1 diabetes with antibiotic therapy. J Immunol 2012; 189: 3805-3814.
-
(2012)
J Immunol
, vol.189
, pp. 3805-3814
-
-
Hara, N.1
Alkanani, A.K.2
Ir, D.3
Robertson, C.E.4
Wagner, B.D.5
Frank, D.N.6
-
16
-
-
0028031142
-
Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor
-
Nicoletti F, di Marcou R, Barcelliniu W, Magro G, Schorlemmeru HU, Kurrleu R, et al. Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor. Eur J Immunol 1994; 24: 1843-1847.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1843-1847
-
-
Nicoletti, F.1
Di Marcou, R.2
Barcelliniu, W.3
Magro, G.4
Schorlemmeru, H.U.5
Kurrleu, R.6
-
17
-
-
84878300647
-
Interleukin-1 antagonism in type 1 diabetes of recent onset: Two multicentre, randomised, double-blind, placebo- controlled trials
-
Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, et al. Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo- controlled trials. Lancet 2013; 381: 1905-1915.
-
(2013)
Lancet
, vol.381
, pp. 1905-1915
-
-
Moran, A.1
Bundy, B.2
Becker, D.J.3
Dimeglio, L.A.4
Gitelman, S.E.5
Goland, R.6
-
18
-
-
0346665756
-
Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations
-
Zipris D, Hillebrands JL, Welsh RM, Rozing J, Xie JX, Mordes JP, et al. Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations. J Immunol 2003; 170: 3592-3602.
-
(2003)
J Immunol
, vol.170
, pp. 3592-3602
-
-
Zipris, D.1
Hillebrands, J.L.2
Welsh, R.M.3
Rozing, J.4
Xie, J.X.5
Mordes, J.P.6
-
19
-
-
0026350805
-
Induction of type i diabetes by Kilhams rat virus in diabetes-resistant BB/Wor rats
-
Guberski DL, Thomas VA, Shek WR, Like AA, Handler ES, Rossini AA, et al. Induction of type I diabetes by Kilhams rat virus in diabetes-resistant BB/Wor rats. Science 1991; 254: 1010-1013.
-
(1991)
Science
, vol.254
, pp. 1010-1013
-
-
Guberski, D.L.1
Thomas, V.A.2
Shek, W.R.3
Like, A.A.4
Handler, E.S.5
Rossini, A.A.6
-
20
-
-
77956409750
-
Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats
-
Valladares R, Sankar D, Li N, Williams E, Lai KK, Abdelgeliel AS, et al. Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. PLoS One 2010; 5: e10507.
-
(2010)
PLoS One
, vol.5
-
-
Valladares, R.1
Sankar, D.2
Li, N.3
Williams, E.4
Lai, K.K.5
Abdelgeliel, A.S.6
-
21
-
-
67349212253
-
DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes
-
Wolter TR, Wong R, Sarkar SA and Zipris D. DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes. Clin Immunol 2009; 132: 103-115.
-
(2009)
Clin Immunol
, vol.132
, pp. 103-115
-
-
Wolter, T.R.1
Wong, R.2
Sarkar, S.A.3
Zipris, D.4
-
22
-
-
84872177147
-
The role of the intestinal microbiota in type 1 diabetes
-
Hara N, Alkanani AK, Ir D, Robertson CE, Wagner BD, Frank DN, et al. The role of the intestinal microbiota in type 1 diabetes. Clin Immunol 2013; 146: 112-119.
-
(2013)
Clin Immunol
, vol.146
, pp. 112-119
-
-
Hara, N.1
Alkanani, A.K.2
Ir, D.3
Robertson, C.E.4
Wagner, B.D.5
Frank, D.N.6
-
23
-
-
10844295809
-
TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats
-
Zipris D, Lien E, Xie JX, Greiner DL, Mordes JP and Rossini AA. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J Immunol 2005; 174: 131-142.
-
(2005)
J Immunol
, vol.174
, pp. 131-142
-
-
Zipris, D.1
Lien, E.2
Xie, J.X.3
Greiner, D.L.4
Mordes, J.P.5
Rossini, A.A.6
-
24
-
-
0036776325
-
Immune responses to the major capsid protein during parvovirus infection of rats
-
Ball-Goodrich LJ, Paturzo FX, Johnson EA, Steger K and Jacoby RO. Immune responses to the major capsid protein during parvovirus infection of rats. J Virol 2002; 76: 10044-10049.
-
(2002)
J Virol
, vol.76
, pp. 10044-10049
-
-
Ball-Goodrich, L.J.1
Paturzo, F.X.2
Johnson, E.A.3
Steger, K.4
Jacoby, R.O.5
-
25
-
-
0033660596
-
Molecular biology of autonomous parvoviruses
-
Hirt B. Molecular biology of autonomous parvoviruses. Contrib Microbiol 2000; 4: 163-177.
-
(2000)
Contrib Microbiol
, vol.4
, pp. 163-177
-
-
Hirt, B.1
-
26
-
-
77950627242
-
IL-1 pathways in inflammation and human diseases
-
Gabay C, Lamacchia C and Palmer G. IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 2010; 6: 232-241.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 232-241
-
-
Gabay, C.1
Lamacchia, C.2
Palmer, G.3
-
27
-
-
84866362664
-
IL-1b mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
-
Coccia M, Harrison OJ, Schiering C, Asquith MJ, Becher B, Powrie F, et al. IL-1b mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells. J Exp Med 2012; 209: 1595-1609.
-
(2012)
J Exp Med
, vol.209
, pp. 1595-1609
-
-
Coccia, M.1
Harrison, O.J.2
Schiering, C.3
Asquith, M.J.4
Becher, B.5
Powrie, F.6
-
28
-
-
84864545087
-
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
-
Dinarello CA, Simon A and Van der Meer JWM. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 2012; 11: 633-652.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 633-652
-
-
Dinarello, C.A.1
Simon, A.2
Van Der Meer, J.W.M.3
-
29
-
-
0026318171
-
Inflammatory cytokines: Interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases
-
Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol 1991; 3: 941-948.
-
(1991)
Curr Opin Immunol
, vol.3
, pp. 941-948
-
-
Dinarello, C.A.1
-
30
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009; 27: 519-550.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
31
-
-
84866601855
-
Dysregulated Toll-like receptor-induced interleukin-1? and interleukin-6 responses in subjects at risk for the development of type 1 diabetes
-
Alkanani AK, Rewers M, Dong F, Waugh K, Gottlieb PA and Zipris D. Dysregulated Toll-like receptor-induced interleukin-1? and interleukin-6 responses in subjects at risk for the development of type 1 diabetes. Diabetes 2012; 61: 2525-2533.
-
(2012)
Diabetes
, vol.61
, pp. 2525-2533
-
-
Alkanani, A.K.1
Rewers, M.2
Dong, F.3
Waugh, K.4
Gottlieb, P.A.5
Zipris, D.6
-
32
-
-
78651345190
-
Altered toll-like receptor signaling pathways in human type 1 diabetes
-
Meyers A, Shah R, Gottlieb P and Zipris D. Altered toll-like receptor signaling pathways in human type 1 diabetes. J Mol Med 2010; 88: 1221-1231.
-
(2010)
J Mol Med
, vol.88
, pp. 1221-1231
-
-
Meyers, A.1
Shah, R.2
Gottlieb, P.3
Zipris, D.4
-
33
-
-
40749100302
-
Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics
-
Wang X, Jia S, Geoffrey R, Alemzadeh R, Ghosh S and Hessner MJ. Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics. J Immunol 2008; 180: 1929-1937.
-
(2008)
J Immunol
, vol.180
, pp. 1929-1937
-
-
Wang, X.1
Jia, S.2
Geoffrey, R.3
Alemzadeh, R.4
Ghosh, S.5
Hessner, M.J.6
-
34
-
-
84555188737
-
Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: Evidence of improved immune regulation
-
Ablamunits V, Henegariu O, Hansen JB, Opare-Addo L, Preston-Hurlburt P, Santamaria P, et al. Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation. Diabetes 2012; 61: 145-154.
-
(2012)
Diabetes
, vol.61
, pp. 145-154
-
-
Ablamunits, V.1
Henegariu, O.2
Hansen, J.B.3
Opare-Addo, L.4
Preston-Hurlburt, P.5
Santamaria, P.6
-
35
-
-
0347360367
-
IL-1 receptor deficiency slows progression to diabetes in the NOD mouse
-
Thomas HE, Irawaty W, Darwiche R, Brodnicki TC, Santamaria P, Allison J, et al. IL-1 receptor deficiency slows progression to diabetes in the NOD mouse. Diabetes 2004; 53: 113-121.
-
(2004)
Diabetes
, vol.53
, pp. 113-121
-
-
Thomas, H.E.1
Irawaty, W.2
Darwiche, R.3
Brodnicki, T.C.4
Santamaria, P.5
Allison, J.6
-
36
-
-
0347086154
-
Caspase-1 is not required for type 1 diabetes in the NOD mouse
-
Schott WH, Haskell BD, Tse HM, Milton MJ, Piganelli JD, Choisy-Rossi CM, et al. Caspase-1 Is not required for type 1 diabetes in the NOD mouse. Diabetes 2004; 53: 99-104.
-
(2004)
Diabetes
, vol.53
, pp. 99-104
-
-
Schott, W.H.1
Haskell, B.D.2
Tse, H.M.3
Milton, M.J.4
Piganelli, J.D.5
Choisy-Rossi, C.M.6
-
37
-
-
0027453552
-
Transcription factors NF-IL6 and NFkappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
-
Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, et al. Transcription factors NF-IL6 and NFkappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. PNAS 1993; 90: 10193-10197.
-
(1993)
PNAS
, vol.90
, pp. 10193-10197
-
-
Matsusaka, T.1
Fujikawa, K.2
Nishio, Y.3
Mukaida, N.4
Matsushima, K.5
Kishimoto, T.6
-
38
-
-
79958703380
-
MiR-365, a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kB
-
Xu Z, Xiao SB, Xu P, Xie Q, Cao L, Wang D, et al. miR-365, a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kB. J Biol Chem 2011; 286: 21401-21412.
-
(2011)
J Biol Chem
, vol.286
, pp. 21401-21412
-
-
Xu, Z.1
Xiao, S.B.2
Xu, P.3
Xie, Q.4
Cao, L.5
Wang, D.6
-
39
-
-
0035500617
-
Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts
-
Deon D, Ahmed S, Tai K, Scaletta N, Herrero C, Lee IH, et al. Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts. J Immunol 2001; 167: 5395-5403.
-
(2001)
J Immunol
, vol.167
, pp. 5395-5403
-
-
Deon, D.1
Ahmed, S.2
Tai, K.3
Scaletta, N.4
Herrero, C.5
Lee, I.H.6
-
40
-
-
62749123000
-
The role of toll-like receptor pathways in the mechanism of type 1 diabetes
-
Lien E and Zipris D. The role of toll-like receptor pathways in the mechanism of type 1 diabetes. Curr Mol Med 2009; 9: 52-68.
-
(2009)
Curr Mol Med
, vol.9
, pp. 52-68
-
-
Lien, E.1
Zipris, D.2
-
41
-
-
0036889996
-
The two faces of IL-6 on Th1/Th2 differentiation
-
Diehl S and Rinccon M. The two faces of IL-6 on Th1/Th2 differentiation. Mol Immunol 2002; 39: 531-536.
-
(2002)
Mol Immunol
, vol.39
, pp. 531-536
-
-
Diehl, S.1
Rinccon, M.2
-
42
-
-
0029768091
-
Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice
-
Hirsch E, Irikura VM, Paul SM and Hirsh D. Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. PNAS 1996; 93: 11008-11013.
-
(1996)
PNAS
, vol.93
, pp. 11008-11013
-
-
Hirsch, E.1
Irikura, V.M.2
Paul, S.M.3
Hirsh, D.4
-
43
-
-
71949118923
-
Free Fatty acids induce a pro-inflammatory response in islets via the abundantly expressed interleukin-1 receptor i
-
Boni-Schnetzler M, Boller S, Debray S, Bouzakri K, Meier DT, Prazak R, et al. Free Fatty acids induce a pro-inflammatory response in islets via the abundantly expressed interleukin-1 receptor I. Endocrinology 2009; 150: 5218-5229.
-
(2009)
Endocrinology
, vol.150
, pp. 5218-5229
-
-
Boni-Schnetzler, M.1
Boller, S.2
Debray, S.3
Bouzakri, K.4
Meier, D.T.5
Prazak, R.6
-
44
-
-
0035668779
-
A choice of death - The signal-transduction of immune-mediated beta-cell apoptosis
-
Eizirik DL and Mandrup-Poulsen T. A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 2001; 44: 2115-2133.
-
(2001)
Diabetologia
, vol.44
, pp. 2115-2133
-
-
Eizirik, D.L.1
Mandrup-Poulsen, T.2
-
45
-
-
0029817047
-
The role of interleukin-1 in the pathogenesis of IDDM
-
Mandrup-Poulsen T. The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 1996; 39: 1005-1029.
-
(1996)
Diabetologia
, vol.39
, pp. 1005-1029
-
-
Mandrup-Poulsen, T.1
-
46
-
-
68949106914
-
The anti-interleukin- 1 in type 1 diabetes action trial-background and rationale
-
Pickersgill LMS and Mandrup-Poulsen TR. The anti-interleukin- 1 in type 1 diabetes action trial-background and rationale. Diabetes Metab Res Rev 2009; 25: 321-324.
-
(2009)
Diabetes Metab Res Rev
, vol.25
, pp. 321-324
-
-
Lms, P.1
Mandrup-Poulsen, T.R.2
|