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Volumn 20, Issue 6, 2014, Pages 574-584

Modulation of virus-induced innateimmunity and type 1 diabetes by IL-1 blockade

Author keywords

Gut bacteria; IL 1 receptor antagonist; Inflammation; Innate immunity; Kilham rat virus; Type 1 diabetes

Indexed keywords

INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1; INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 12; COMPLEMENTARY DNA; INTERLEUKIN 23; RNA;

EID: 84907050797     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425913502242     Document Type: Article
Times cited : (17)

References (46)
  • 2
    • 15644377395 scopus 로고    scopus 로고
    • Immunological heterogeneity in type i diabetes: Presence of distinct autoAb patterns in patients with acute onset and slowly progressive disease
    • Seissler J, de Sonnaville JJ, Morgenthaler NG, Steinbrenner H, Glawe D, Khoo-Morgenthaler UY, et al. Immunological heterogeneity in type I diabetes: presence of distinct autoAb patterns in patients with acute onset and slowly progressive disease. Diabetologia 1998; 41: 891-897.
    • (1998) Diabetologia , vol.41 , pp. 891-897
    • Seissler, J.1    De Sonnaville, J.J.2    Morgenthaler, N.G.3    Steinbrenner, H.4    Glawe, D.5    Khoo-Morgenthaler, U.Y.6
  • 4
    • 16244396427 scopus 로고    scopus 로고
    • The Stages of Type 1A Diabetes 2005
    • Gianani R and Eisenbarth GS. The stages of type 1A diabetes: 2005. Immunol Rev 2005; 204: 232-249.
    • (2005) Immunol Rev , vol.204 , pp. 232-249
    • Gianani, R.1    Eisenbarth, G.S.2
  • 5
    • 0035076588 scopus 로고    scopus 로고
    • The role of viruses in Type i diabetes: Two distinct cellular and molecular pathogenic mechanisms of virusinduced diabetes in animals
    • Jun HS and Yoon JW. The role of viruses in Type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virusinduced diabetes in animals. Diabetologia 2001; 44: 271-285.
    • (2001) Diabetologia , vol.44 , pp. 271-285
    • Jun, H.S.1    Yoon, J.W.2
  • 6
    • 0037217057 scopus 로고    scopus 로고
    • A new took at viruses in type 1 diabetes
    • Jun HS and Yoon JW. A new took at viruses in type 1 diabetes. Diabetes Metab Res Rev 2003; 19: 8-31.
    • (2003) Diabetes Metab Res Rev , vol.19 , pp. 8-31
    • Jun, H.S.1    Yoon, J.W.2
  • 8
    • 24144449831 scopus 로고    scopus 로고
    • LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation
    • Mordes JP, Guberski DL, Leif JH, Woda BA, Flanagan JF, Greiner DL, et al. LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation. Diabetes 2005; 54: 2727-2733.
    • (2005) Diabetes , vol.54 , pp. 2727-2733
    • Mordes, J.P.1    Guberski, D.L.2    Leif, J.H.3    Woda, B.A.4    Flanagan, J.F.5    Greiner, D.L.6
  • 9
    • 63249107452 scopus 로고    scopus 로고
    • Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms
    • Zipris D. Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms. Clin Immunol 2009; 131: 11-23.
    • (2009) Clin Immunol , vol.131 , pp. 11-23
    • Zipris, D.1
  • 10
    • 0029665016 scopus 로고    scopus 로고
    • Kilham rat triggers T-cell-dependent autoimmune diabetes in multiple strains of rat
    • Ellerman KE, Richards CA, Guberski DL, Shek WR and Like AA. Kilham rat triggers T-cell-dependent autoimmune diabetes in multiple strains of rat. Diabetes 1996; 45: 557-562.
    • (1996) Diabetes , vol.45 , pp. 557-562
    • Ellerman, K.E.1    Richards, C.A.2    Guberski, D.L.3    Shek, W.R.4    Like, A.A.5
  • 11
    • 55249122121 scopus 로고    scopus 로고
    • Innate immunity and its role in type 1 diabetes
    • Zipris D. Innate immunity and its role in type 1 diabetes. Curr Opin Endocrinol Diabetes Obes 2008; 15: 326-331.
    • (2008) Curr Opin Endocrinol Diabetes Obes , vol.15 , pp. 326-331
    • Zipris, D.1
  • 12
    • 77953953485 scopus 로고    scopus 로고
    • Toll-like receptors and type 1 diabetes
    • Zipris D. Toll-like receptors and type 1 diabetes. Adv Exp Med Biol 2010; 654: 585-610.
    • (2010) Adv Exp Med Biol , vol.654 , pp. 585-610
    • Zipris, D.1
  • 13
    • 77951880662 scopus 로고    scopus 로고
    • Brief dexamethasone treatment during acute infection prevents virus-induced autoimmune diabetes
    • Londono P, Komura A, Hara N and Zipris D. Brief dexamethasone treatment during acute infection prevents virus-induced autoimmune diabetes. Clin Immunol 2010; 135: 401-411.
    • (2010) Clin Immunol , vol.135 , pp. 401-411
    • Londono, P.1    Komura, A.2    Hara, N.3    Zipris, D.4
  • 16
    • 0028031142 scopus 로고
    • Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor
    • Nicoletti F, di Marcou R, Barcelliniu W, Magro G, Schorlemmeru HU, Kurrleu R, et al. Protection from experimental autoimmune diabetes in the non-obese diabetic mouse with soluble interleukin-1 receptor. Eur J Immunol 1994; 24: 1843-1847.
    • (1994) Eur J Immunol , vol.24 , pp. 1843-1847
    • Nicoletti, F.1    Di Marcou, R.2    Barcelliniu, W.3    Magro, G.4    Schorlemmeru, H.U.5    Kurrleu, R.6
  • 17
    • 84878300647 scopus 로고    scopus 로고
    • Interleukin-1 antagonism in type 1 diabetes of recent onset: Two multicentre, randomised, double-blind, placebo- controlled trials
    • Moran A, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, et al. Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo- controlled trials. Lancet 2013; 381: 1905-1915.
    • (2013) Lancet , vol.381 , pp. 1905-1915
    • Moran, A.1    Bundy, B.2    Becker, D.J.3    Dimeglio, L.A.4    Gitelman, S.E.5    Goland, R.6
  • 18
    • 0346665756 scopus 로고    scopus 로고
    • Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations
    • Zipris D, Hillebrands JL, Welsh RM, Rozing J, Xie JX, Mordes JP, et al. Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations. J Immunol 2003; 170: 3592-3602.
    • (2003) J Immunol , vol.170 , pp. 3592-3602
    • Zipris, D.1    Hillebrands, J.L.2    Welsh, R.M.3    Rozing, J.4    Xie, J.X.5    Mordes, J.P.6
  • 19
    • 0026350805 scopus 로고
    • Induction of type i diabetes by Kilhams rat virus in diabetes-resistant BB/Wor rats
    • Guberski DL, Thomas VA, Shek WR, Like AA, Handler ES, Rossini AA, et al. Induction of type I diabetes by Kilhams rat virus in diabetes-resistant BB/Wor rats. Science 1991; 254: 1010-1013.
    • (1991) Science , vol.254 , pp. 1010-1013
    • Guberski, D.L.1    Thomas, V.A.2    Shek, W.R.3    Like, A.A.4    Handler, E.S.5    Rossini, A.A.6
  • 20
    • 77956409750 scopus 로고    scopus 로고
    • Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats
    • Valladares R, Sankar D, Li N, Williams E, Lai KK, Abdelgeliel AS, et al. Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BB-DP rats. PLoS One 2010; 5: e10507.
    • (2010) PLoS One , vol.5
    • Valladares, R.1    Sankar, D.2    Li, N.3    Williams, E.4    Lai, K.K.5    Abdelgeliel, A.S.6
  • 21
    • 67349212253 scopus 로고    scopus 로고
    • DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes
    • Wolter TR, Wong R, Sarkar SA and Zipris D. DNA microarray analysis for the identification of innate immune pathways implicated in virus-induced autoimmune diabetes. Clin Immunol 2009; 132: 103-115.
    • (2009) Clin Immunol , vol.132 , pp. 103-115
    • Wolter, T.R.1    Wong, R.2    Sarkar, S.A.3    Zipris, D.4
  • 23
    • 10844295809 scopus 로고    scopus 로고
    • TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats
    • Zipris D, Lien E, Xie JX, Greiner DL, Mordes JP and Rossini AA. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. J Immunol 2005; 174: 131-142.
    • (2005) J Immunol , vol.174 , pp. 131-142
    • Zipris, D.1    Lien, E.2    Xie, J.X.3    Greiner, D.L.4    Mordes, J.P.5    Rossini, A.A.6
  • 24
    • 0036776325 scopus 로고    scopus 로고
    • Immune responses to the major capsid protein during parvovirus infection of rats
    • Ball-Goodrich LJ, Paturzo FX, Johnson EA, Steger K and Jacoby RO. Immune responses to the major capsid protein during parvovirus infection of rats. J Virol 2002; 76: 10044-10049.
    • (2002) J Virol , vol.76 , pp. 10044-10049
    • Ball-Goodrich, L.J.1    Paturzo, F.X.2    Johnson, E.A.3    Steger, K.4    Jacoby, R.O.5
  • 25
    • 0033660596 scopus 로고    scopus 로고
    • Molecular biology of autonomous parvoviruses
    • Hirt B. Molecular biology of autonomous parvoviruses. Contrib Microbiol 2000; 4: 163-177.
    • (2000) Contrib Microbiol , vol.4 , pp. 163-177
    • Hirt, B.1
  • 26
    • 77950627242 scopus 로고    scopus 로고
    • IL-1 pathways in inflammation and human diseases
    • Gabay C, Lamacchia C and Palmer G. IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol 2010; 6: 232-241.
    • (2010) Nat Rev Rheumatol , vol.6 , pp. 232-241
    • Gabay, C.1    Lamacchia, C.2    Palmer, G.3
  • 27
    • 84866362664 scopus 로고    scopus 로고
    • IL-1b mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
    • Coccia M, Harrison OJ, Schiering C, Asquith MJ, Becher B, Powrie F, et al. IL-1b mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells. J Exp Med 2012; 209: 1595-1609.
    • (2012) J Exp Med , vol.209 , pp. 1595-1609
    • Coccia, M.1    Harrison, O.J.2    Schiering, C.3    Asquith, M.J.4    Becher, B.5    Powrie, F.6
  • 28
    • 84864545087 scopus 로고    scopus 로고
    • Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
    • Dinarello CA, Simon A and Van der Meer JWM. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 2012; 11: 633-652.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 633-652
    • Dinarello, C.A.1    Simon, A.2    Van Der Meer, J.W.M.3
  • 29
    • 0026318171 scopus 로고
    • Inflammatory cytokines: Interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases
    • Dinarello CA. Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Curr Opin Immunol 1991; 3: 941-948.
    • (1991) Curr Opin Immunol , vol.3 , pp. 941-948
    • Dinarello, C.A.1
  • 30
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009; 27: 519-550.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 31
    • 84866601855 scopus 로고    scopus 로고
    • Dysregulated Toll-like receptor-induced interleukin-1? and interleukin-6 responses in subjects at risk for the development of type 1 diabetes
    • Alkanani AK, Rewers M, Dong F, Waugh K, Gottlieb PA and Zipris D. Dysregulated Toll-like receptor-induced interleukin-1? and interleukin-6 responses in subjects at risk for the development of type 1 diabetes. Diabetes 2012; 61: 2525-2533.
    • (2012) Diabetes , vol.61 , pp. 2525-2533
    • Alkanani, A.K.1    Rewers, M.2    Dong, F.3    Waugh, K.4    Gottlieb, P.A.5    Zipris, D.6
  • 32
    • 78651345190 scopus 로고    scopus 로고
    • Altered toll-like receptor signaling pathways in human type 1 diabetes
    • Meyers A, Shah R, Gottlieb P and Zipris D. Altered toll-like receptor signaling pathways in human type 1 diabetes. J Mol Med 2010; 88: 1221-1231.
    • (2010) J Mol Med , vol.88 , pp. 1221-1231
    • Meyers, A.1    Shah, R.2    Gottlieb, P.3    Zipris, D.4
  • 33
    • 40749100302 scopus 로고    scopus 로고
    • Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics
    • Wang X, Jia S, Geoffrey R, Alemzadeh R, Ghosh S and Hessner MJ. Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics. J Immunol 2008; 180: 1929-1937.
    • (2008) J Immunol , vol.180 , pp. 1929-1937
    • Wang, X.1    Jia, S.2    Geoffrey, R.3    Alemzadeh, R.4    Ghosh, S.5    Hessner, M.J.6
  • 34
    • 84555188737 scopus 로고    scopus 로고
    • Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: Evidence of improved immune regulation
    • Ablamunits V, Henegariu O, Hansen JB, Opare-Addo L, Preston-Hurlburt P, Santamaria P, et al. Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation. Diabetes 2012; 61: 145-154.
    • (2012) Diabetes , vol.61 , pp. 145-154
    • Ablamunits, V.1    Henegariu, O.2    Hansen, J.B.3    Opare-Addo, L.4    Preston-Hurlburt, P.5    Santamaria, P.6
  • 37
    • 0027453552 scopus 로고
    • Transcription factors NF-IL6 and NFkappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, et al. Transcription factors NF-IL6 and NFkappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. PNAS 1993; 90: 10193-10197.
    • (1993) PNAS , vol.90 , pp. 10193-10197
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6
  • 38
    • 79958703380 scopus 로고    scopus 로고
    • MiR-365, a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kB
    • Xu Z, Xiao SB, Xu P, Xie Q, Cao L, Wang D, et al. miR-365, a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kB. J Biol Chem 2011; 286: 21401-21412.
    • (2011) J Biol Chem , vol.286 , pp. 21401-21412
    • Xu, Z.1    Xiao, S.B.2    Xu, P.3    Xie, Q.4    Cao, L.5    Wang, D.6
  • 39
    • 0035500617 scopus 로고    scopus 로고
    • Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts
    • Deon D, Ahmed S, Tai K, Scaletta N, Herrero C, Lee IH, et al. Cross-talk between IL-1 and IL-6 signaling pathways in rheumatoid arthritis synovial fibroblasts. J Immunol 2001; 167: 5395-5403.
    • (2001) J Immunol , vol.167 , pp. 5395-5403
    • Deon, D.1    Ahmed, S.2    Tai, K.3    Scaletta, N.4    Herrero, C.5    Lee, I.H.6
  • 40
    • 62749123000 scopus 로고    scopus 로고
    • The role of toll-like receptor pathways in the mechanism of type 1 diabetes
    • Lien E and Zipris D. The role of toll-like receptor pathways in the mechanism of type 1 diabetes. Curr Mol Med 2009; 9: 52-68.
    • (2009) Curr Mol Med , vol.9 , pp. 52-68
    • Lien, E.1    Zipris, D.2
  • 41
    • 0036889996 scopus 로고    scopus 로고
    • The two faces of IL-6 on Th1/Th2 differentiation
    • Diehl S and Rinccon M. The two faces of IL-6 on Th1/Th2 differentiation. Mol Immunol 2002; 39: 531-536.
    • (2002) Mol Immunol , vol.39 , pp. 531-536
    • Diehl, S.1    Rinccon, M.2
  • 42
    • 0029768091 scopus 로고    scopus 로고
    • Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice
    • Hirsch E, Irikura VM, Paul SM and Hirsh D. Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. PNAS 1996; 93: 11008-11013.
    • (1996) PNAS , vol.93 , pp. 11008-11013
    • Hirsch, E.1    Irikura, V.M.2    Paul, S.M.3    Hirsh, D.4
  • 43
    • 71949118923 scopus 로고    scopus 로고
    • Free Fatty acids induce a pro-inflammatory response in islets via the abundantly expressed interleukin-1 receptor i
    • Boni-Schnetzler M, Boller S, Debray S, Bouzakri K, Meier DT, Prazak R, et al. Free Fatty acids induce a pro-inflammatory response in islets via the abundantly expressed interleukin-1 receptor I. Endocrinology 2009; 150: 5218-5229.
    • (2009) Endocrinology , vol.150 , pp. 5218-5229
    • Boni-Schnetzler, M.1    Boller, S.2    Debray, S.3    Bouzakri, K.4    Meier, D.T.5    Prazak, R.6
  • 44
    • 0035668779 scopus 로고    scopus 로고
    • A choice of death - The signal-transduction of immune-mediated beta-cell apoptosis
    • Eizirik DL and Mandrup-Poulsen T. A choice of death - the signal-transduction of immune-mediated beta-cell apoptosis. Diabetologia 2001; 44: 2115-2133.
    • (2001) Diabetologia , vol.44 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 45
    • 0029817047 scopus 로고    scopus 로고
    • The role of interleukin-1 in the pathogenesis of IDDM
    • Mandrup-Poulsen T. The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 1996; 39: 1005-1029.
    • (1996) Diabetologia , vol.39 , pp. 1005-1029
    • Mandrup-Poulsen, T.1
  • 46
    • 68949106914 scopus 로고    scopus 로고
    • The anti-interleukin- 1 in type 1 diabetes action trial-background and rationale
    • Pickersgill LMS and Mandrup-Poulsen TR. The anti-interleukin- 1 in type 1 diabetes action trial-background and rationale. Diabetes Metab Res Rev 2009; 25: 321-324.
    • (2009) Diabetes Metab Res Rev , vol.25 , pp. 321-324
    • Lms, P.1    Mandrup-Poulsen, T.R.2


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