CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer

Journal of Cell Science

Volumn 127, Issue 18, 2014, Pages 3893-3901

  Macpherson, Iain R ^a,b   Rainero, Elena ^a   Mitchell, Louise E ^a   van den Berghe, Peter V E ^a   Speirs, Claire ^a   Dozynkiewicz, Marta A ^a   Chaudhary, Suman ^a   Kalna, Gabriela ^a   Edwards, Joanne ^b   Timpson, Paul ^a   Norman, Jim C ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Breast cancer; CLIC3; DCIS; ER negative; Invasion; Late endosome; MMP14; MT1 MMP; Recycling

Indexed keywords

ALPHA6 INTEGRIN; BETA4 INTEGRIN; CHLORIDE INTRACELLULAR CHANNEL PROTEIN 3; COLLAGEN TYPE 1; ESTROGEN RECEPTOR; KALININ; MATRIGEL; MATRIX METALLOPROTEINASE 14; PROTEIN; UNCLASSIFIED DRUG; CHLORIDE CHANNEL; CLIC3 PROTEIN, HUMAN; MMP14 PROTEIN, HUMAN;

ARTICLE; BASEMENT MEMBRANE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST METASTASIS; CANCER PROGNOSIS; CANCER SURVIVAL; CELL ADHESION; CELL COMPARTMENTALIZATION; CELL CULTURE; CELL MEMBRANE; CELL MIGRATION; ENDOSOME; EXTRACELLULAR MATRIX; FEMALE; HUMAN; LYSOSOME; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR INVASION; BREAST TUMOR; CELL MOTION; GENETICS; METABOLISM; METASTASIS; PATHOLOGY; PATHOPHYSIOLOGY; PROTEIN TRANSPORT; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHLORIDE CHANNELS; ENDOSOMES; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 14; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROTEIN TRANSPORT;

EID: 84907042768     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.135947     Document Type: Article

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