c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Tobar, Nicolás ^a   Toyos, Marcela ^a   Urra, Carla ^a   Méndez, Nicolás ^a   Arancibia, Rodrigo ^b   Smith, Patricio C ^b   Martínez, Jorge ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Fibrosis; JNK; NOX 4; ROS

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1; ACTA2 PROTEIN, HUMAN; ACTIN; CTGF PROTEIN, HUMAN; NOX4 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TGFB1 PROTEIN, HUMAN;

ALPHA SMA GENE; ARTICLE; BREAST STROMAL CELL; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CONTROLLED STUDY; CTGF GENE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; MOLECULAR DYNAMICS; MYOFIBROBLAST; NOX 4 GENE; OXIDATION REDUCTION STATE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STROMA CELL; TUMOR MICROENVIRONMENT; BREAST; CELL LINE; CYTOLOGY; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; HEK293 CELL LINE; METABOLISM; PATHOLOGY;

ACTINS; BREAST; CELL DIFFERENTIATION; CELL LINE; CONNECTIVE TISSUE GROWTH FACTOR; FEMALE; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MYOFIBROBLASTS; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84907033145     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-640     Document Type: Article

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