Anxiety- and depression-like behavior and impaired neurogenesis evoked by peripheral neuropathy persist following resolution of prolonged tactile hypersensitivity

Journal of Neuroscience

Volumn 34, Issue 37, 2014, Pages 12304-12312

  Dimitrov, Eugene L ^a,b   Tsuda, Mumeko C ^a   Usdin, Ted B ^a   Cameron, Heather A ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

Adult neurogenesis; Chronic pain; Depression; Neuropathic pain; Reversible neuropathic injury; Sciatic nerve

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NEUROKININ 1 RECEPTOR; NEUROKININ A; NEUROPEPTIDE GAMMA; NEUROPEPTIDE K; PREPROTACHYKININ; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNTING; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MOUSE; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; ANIMAL BEHAVIOR; ANXIETY; C57BL MOUSE; COMPLICATION; DEPRESSION; ETIOLOGY; HYPERALGESIA; MENTAL DISORDERS; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEURALGIA; PATHOPHYSIOLOGY; PHYSIOLOGY; SCIATIC NEUROPATHY; TOUCH;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; DEPRESSION; HYPERALGESIA; MALE; MENTAL DISORDERS; MICE; MICE, INBRED C57BL; NEURALGIA; NEUROGENESIS; NEURONAL PLASTICITY; SCIATIC NEUROPATHY; TOUCH;

EID: 84907014181     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0312-14.2014     Document Type: Article

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