Polymer multilayers loaded with antifungal β-peptides kill planktonic Candida albicans and reduce formation of fungal biofilms on the surfaces of flexible catheter tubes

Journal of Controlled Release

Volumn 191, Issue , 2014, Pages 54-62

  Raman, Namrata ^a   Lee, Myung Ryul ^a   Palecek, Sean P ^a   Lynn, David M ^a,b  

^a Wisconsin Electric Machines and Power Electronics Consortium   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Antifungal; Biofilms; Catheters; Controlled release; Polymer multilayers; Surfaces

Indexed keywords

AMINO ACIDS; BIOCOMPATIBILITY; BIOFILMS; BIOMEDICAL EQUIPMENT; CANDIDA; CATHETERS; FABRICATION; FUNGI; FUNGICIDES; MULTILAYERS; PEPTIDES; PLASTIC COATINGS; POLYELECTROLYTES; POLYPEPTIDES; SURFACES; YEAST;

ANTI-FUNGAL; CONTROLLED RELEASE; HOSPITAL ACQUIRED INFECTION; LAYER-BY-LAYER APPROACHES; LAYER-BY-LAYER FABRICATION; PERSONAL CARE APPLICATIONS; POLYELECTROLYTE MULTILAYER; POLYMER MULTILAYERS;

ANTIFUNGAL AGENTS;

ANTIFUNGAL AGENT; ANTIFUNGAL BETA PEPTIDE; POLYETHYLENE; POLYGLUTAMIC ACID; POLYLYSINE; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; BIOMATERIAL; DRUG CARRIER;

ANTIFUNGAL ACTIVITY; ARTICLE; BILAYER MEMBRANE; BIOFILM; CANDIDA ALBICANS; CELL METABOLISM; CONTROLLED STUDY; DEVICE INFECTION; DEVICE REMOVAL; DRUG DELIVERY DEVICE; ELLIPSOMETRY; ENVIRONMENTAL FACTOR; EXTRACELLULAR MATRIX; FLUORESCENCE MICROSCOPY; FUNGAL BIOFILM; HEMOLYSIS; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; INCIDENCE; INDWELLING CATHETER; INOCULATION; MINIMUM INHIBITORY CONCENTRATION; MYCOSIS; NANOFABRICATION; NONHUMAN; PHASE CONTRAST MICROSCOPY; POLYELECTROLYTE MULTILAYER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SLOW DRUG RELEASE; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; XTT ASSAY; CATHETER; CATHETER-RELATED INFECTIONS; CHEMISTRY; DRUG EFFECTS; EQUIPMENT DESIGN; GROWTH, DEVELOPMENT AND AGING; KINETICS; MEDICAL DEVICE CONTAMINATION; MEDICINAL CHEMISTRY; MICROBIOLOGY; PHARMACEUTICS; PROCEDURES; SOLUBILITY;

ANTIFUNGAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BIOFILMS; CANDIDA ALBICANS; CATHETER-RELATED INFECTIONS; CATHETERS; CHEMISTRY, PHARMACEUTICAL; COATED MATERIALS, BIOCOMPATIBLE; DRUG CARRIERS; EQUIPMENT CONTAMINATION; EQUIPMENT DESIGN; KINETICS; POLYGLUTAMIC ACID; POLYLYSINE; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84906948468     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.05.026     Document Type: Article

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