Predictive modeling of gingivitis severity and susceptibility via oral microbiota

ISME Journal

Volumn 8, Issue 9, 2014, Pages 1768-1780

  Huang, Shi ^a,b   Li, Rui ^c   Zeng, Xiaowei ^a   He, Tao ^d   Zhao, Helen ^c   Chang, Alice ^c   Bo, Cunpei ^a   Chen, Jie ^a   Yang, Fang ^e   Knight, Rob ^f   Liu, Jiquan ^c   Davis, Catherine ^g   Xu, Jian ^a  

^a Qingdao institute of bioenergy and bioprocess technology   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c PROCTER AND GAMBLE COMPANY   (United States)

^d Department of Oral Care Clinical Operation Procter Gamble Mason Business Center   (United States)

^e QINGDAO MUNICIPAL HOSPITAL   (China)

^f UNIVERSITY OF COLORADO   (United States)

^g Procter and Gamble   (United States)

Author keywords

gingivitis; metagenomics; microbial indices of gingivitis; plaque

Indexed keywords

BACTERIUM; DENTAL HEALTH; DISEASE SEVERITY; GENOMICS; MICROBIAL COMMUNITY; MODELING; PUBLIC HEALTH;

BACTERIA (MICROORGANISMS);

ADULT; BACTERIUM; BIOLOGICAL MODEL; CLASSIFICATION; DISEASE COURSE; FEMALE; GENETICS; GINGIVITIS; HUMAN; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; MICROFLORA; MOUTH; PERIODONTICS; PHENOTYPE;

ADULT; BACTERIA; DISEASE PROGRESSION; FEMALE; GINGIVITIS; HUMANS; MALE; MICROBIOTA; MODELS, BIOLOGICAL; MOUTH; PERIODONTAL INDEX; PHENOTYPE;

EID: 84906942512     PISSN: 17517362     EISSN: 17517370     Source Type: Journal    
DOI: 10.1038/ismej.2014.32     Document Type: Article

References (48)

1. Caporaso JG, Lauber CL, Costello EK, Berg-Lyons D, Gonzalez A, Stombaugh J et al. 2011 Moving pictures of the human microbiome. Genome Biol 12: R50.
2. Eick S, Pietkiewicz M, Sculean A. 2013 Oral microbiota in Swiss adolescents. Clin Oral Investig 17: 79-86.
3. Faith JJ, McNulty NP, Rey FE, Gordon JI. 2011 Predicting a human gut microbiota's response to diet in gnotobiotic mice. Science 333: 101-104.
4. Filoche S, Wong L, Sissons CH. 2010 Oral biofilms: emerging concepts in microbial ecology. J Dent Res 89: 8-18.
5. Grant MM, Creese AJ, Barr G, Ling MR, Scott AE, Matthews JB et al. 2010 Proteomic analysis of a noninvasive human model of acute inflammation and its resolution: the twenty-one day gingivitis model. J Proteome Res 9: 4732-4744.
6. Griffen AL, Beall CJ, Campbell JH, Firestone ND, Kumar PS, Yang ZK et al. 2012 Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing. ISME J 6: 1176-1185.
7. Haffajee AD, Socransky SS, Patel MR, Song X. (2008). Microbial complexes in supragingival plaque. Oral Microbiol Immunol 23: 196-205.
8. Hamady M, Lozupone C, Knight R. 2010 Fast UniFrac: facilitating high-throughput phylogenetic analyses of microbial communities including analysis of pyrosequencing and PhyloChip data. ISME J 4: 17-27.
9. Handfield M, Baker HV, Lamont RJ. (2008). Beyond good and evil in the oral cavity: Insights into host-microbe relationships derived from transcriptional profiling of gingival cells. J Dent Res 87: 203-223.
10. Haya S, Tokumaru Y, Abe N, Kaneko J, Aizawa S. 2011 Characterization of lateral flagella of Selenomonas ruminantium. Appl Environ Microbiol 77: 2799-2802.
11. Huang S, Yang F, Zeng X, Chen J, Li R, Wen T et al. 2011 Preliminary characterization of the oral microbiota of Chinese adults with and without gingivitis. BMC Oral Health 11: 33.
12. Igic M, Kesic L, Lekovic V, Apostolovic M, Mihailovic D, Kostadinovic L et al. 2012 Chronic gingivitis: the prevalence of periodontopathogens and therapy efficiency. Eur J Clin Microbiol Infect Dis 31: 1911-1915.
13. Ihara H, Miura T, Kato T, Ishihara K, Nakagawa T, Yamada S et al. (2003). Detection of Campylobacter rectus in periodontitis sites by monoclonal antibodies. J Periodontal Res 38: 64-72.
14. Jin LJ, Armitage GC, Klinge B, Lang NP, Tonetti M, Williams RC. 2011 Global oral health inequalities: task group-periodontal disease. Adv Dent Res 23: 221-226.
15. Kistler JO, Booth V, Bradshaw DJ, Wade WG.2013 Bacterial community development in experimental gingivitis. PLoS One 8: e71227.
16. Knights D, Parfrey LW, Zaneveld J, Lozupone C, Knight R. 2011 Human-associated microbial signatures: examining their predictive value. Cell Host Microbe 10: 292-296.
17. Koren O, Spor A, Felin J, Fak F, Stombaugh J, Tremaroli V et al. 2011 Human oral, gut, and plaque microbiota in patients with atherosclerosis. Proc Natl Acad Sci USA 108(Suppl 1): 4592-4598.
18. Koren O, Knights D, Gonzalez A, Waldron L, Segata N, Knight R et al.2013 A guide to enterotypes across the human body: meta-analysis of microbial community structures in human microbiome datasets. PLoS Comput Biol 9: e1002863.
19. Kornman KS. (2008). Mapping the pathogenesis of periodontitis: a new look. J Periodontol 79: 1560-1568.
20. Lee A, Ghaname CB, Braun TM, Sugai JV, Teles RP, Loesche WJ et al. 2012 Bacterial and salivary biomarkers predict the gingival inflammatory profile. J Periodontol 83: 79-89.
21. Liu J, Howell JK, Bradley SD, Zheng YS, Zhou ZH, Norris SJ. 2010 Cellular architecture of treponema pallidum: novel flagellum, periplasmic cone, and cell envelope as revealed by cryo electron tomography. J Mol Biol 403: 546-561.
22. Loe H, Theilade E, Jensen SB. (1965). Experimental gingivitis in man. J Periodontol 36: 177-187.
23. Loesche W. (2007). Dental caries and periodontitis: contrasting two infections that have medical implications. Infect Dis Clin North Am 21: 471-502. vii.
24. Lozupone CA, Stombaugh JI, Gordon JI, Jansson JK, Knight R. 2012 Diversity, stability and resilience of the human gut microbiota. Nature 489: 220-230.
25. Mariotti A. (1999). Dental plaque-induced gingival diseases. Ann Periodontol 4: 7-19.
26. Moore LVH, Moore WEC, Cato EP, Smibert RM, Burmeister JA, Best AM et al. (1987). Bacteriology of human gingivitis. J Dent Res 66: 989-995.
27. Muegge BD, Kuczynski J, Knights D, Clemente JC, Gonzalez A, Fontana L et al. 2011 Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans. Science 332: 970-974.
28. Offenbacher S, Barros SP, Paquette DW, Winston JL, Biesbrock AR, Thomason RG et al. (2009). Gingival transcriptome patterns during induction and resolution of experimental gingivitis in humans. J Periodontol 80: 1963-1982.
29. Oliver RC, Brown LJ, Loe H. (1991). Variations in the prevalence and extent of periodontitis. J Am Dent Assoc 122: 43-48.
30. Oliver RC, Brown LJ, Loe H. (1998). Periodontal diseases in the United States population. J Periodontol 69: 269-278.
31. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C. (2005). The global burden of oral diseases and risks to oral health. Bull World Health Organ 83: 661-669.
32. Qin J, Li Y, Cai Z, Li S, Zhu J, Zhang F et al. 2012 A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490: 55-60.
33. Ramseier CA, Kinney JS, Herr AE, Braun T, Sugai JV, Shelburne CA et al. (2009). Identification of pathogen and host-response markers correlated with periodontal disease. J Periodontol 80: 436-446.
34. Ruby JD, Li H, Kuramitsu H, Norris SJ, Goldstein SF, Buttle KF et al. (1997). Relationship of Treponema denticola periplasmic flagella to irregular cell morphology. J Bacteriol 179: 1628-1635.
35. Savitt ED, Socransky SS. (1984). Distribution of certain subgingival microbial species in selected periodontal conditions. J Periodontal Res 19: 111-123.
36. Sharma N, Charles CH, Lynch MC, Qaqish J, McGuire JA, Galustians JG et al. (2004). Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month study. J Am Dent Assoc 135: 496-504.
37. Sheiham A. (1997). Is the chemical prevention of gingivitis necessary to prevent severe periodontitis Periodontol 2000 15: 15-24.
38. Siqueira Jr JF, Rocas IN. (2007). Bacterial pathogenesis and mediators in apical periodontitis. Braz Dent J 18: 267-280.
39. Socransky SS, Haffajee AD, Cugini MA, Smith C, Kent Jr RL. (1998). Microbial complexes in subgingival plaque. J Clin Periodontol 25: 134-144.
40. Tanner A, Maiden MF, Macuch PJ, Murray LL, Kent Jr RL. (1998). Microbiota of health, gingivitis, and initial periodontitis. J Clin Periodontol 25: 85-98.
41. Tanner AC, Paster BJ, Lu SC, Kanasi E, Kent Jr R, Van Dyke T et al. (2006). Subgingival and tongue microbiota during early periodontitis. J Dent Res 85: 318-323.
42. Tatakis DN, Trombelli L. (2004). Modulation of clinical expression of plaque-induced gingivitis. I. Background review and rationale. J Clin Periodontol 31: 229-238.
43. Tatusov RL, Natale DA, Garkavtsev IV, Tatusova TA, Shankavaram UT, Rao BS et al. (2001). The COG database: new developments in phylogenetic classification of proteins from complete genomes. Nucleic Acids Res 29: 22-28.
44. Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE et al. (2009). A core gut microbiome in obese and lean twins. Nature 457: 480-484.
45. van der Weijden GA, Timmerman MF, Piscaer M, Snoek I, van der Velden U, Galgut PN. (2002). Effectiveness of an electrically active brush in the removal of overnight plaque and treatment of gingivitis. J Clin Periodontol 29: 699-704.
46. Wang JF, Qi J, Zhao H, He S, Zhang YF, Wei SC et al.2013 Metagenomic sequencing reveals microbiota and its functional potential associated with periodontal disease. Sci Rep 3: 1843.
47. Williams RC. (1990). Periodontal disease. N Engl J Med 322: 373-382.
48. Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA et al. 2011 Linking long-term dietary patterns with gut microbial enterotypes. Science 334: 105-108.