Candida in the respiratory tract secretions of critically ill patients and the impact of antifungal treatment: A randomized placebo controlled pilot trial (CANTREAT study)

Intensive Care Medicine

Volumn 40, Issue 9, 2014, Pages 1313-1322

  Albert, Martin ^a   Williamson, David ^a   Muscedere, John ^b   Lauzier, Francois ^c   Rotstein, Coleman ^d   Kanji, Salmaan ^e   Jiang, Xuran ^f   Hall, Mark ^g   Heyland, Daren ^b,f  

^a HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^b KINGSTON GENERAL HOSPITAL   (Canada)

^c LAVAL UNIVERSITY   (Canada)

^d TORONTO GENERAL HOSPITAL   (Canada)

^e OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^f QUEEN S UNIVERSITY   (Canada)

^g THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Antifungal therapy; Candida infection; Intensive care; Nosocomial infection; Pneumonia

Indexed keywords

ANIDULAFUNGIN; ANTIFUNGAL AGENT; FLUCONAZOLE; PLACEBO; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AIRWAY; ARTICLE; BLOOD LEVEL; CANDIDA; CANDIDA ALBICANS; CANDIDA GLABRATA; CONTROLLED STUDY; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; CYTOKINE PRODUCTION; DISEASE MARKER; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; INNATE IMMUNITY; INTENSIVE CARE UNIT; MALE; MULTICENTER STUDY; NONHUMAN; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFLAMMATION; TREATMENT OUTCOME; VENTILATOR ASSOCIATED PNEUMONIA; CANDIDIASIS; CLINICAL TRIAL; ISOLATION AND PURIFICATION; LUNG LAVAGE; MICROBIOLOGY; MIDDLE AGED; PNEUMONIA, VENTILATOR-ASSOCIATED; PROSPECTIVE STUDY; RESPIRATORY SYSTEM; SECRETION (PROCESS);

ANTIFUNGAL AGENTS; BRONCHOALVEOLAR LAVAGE FLUID; CANDIDA; CANDIDIASIS; CRITICAL ILLNESS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; PNEUMONIA, VENTILATOR-ASSOCIATED; PROSPECTIVE STUDIES; RESPIRATORY SYSTEM;

EID: 84906940700     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-014-3352-2     Document Type: Article

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