Fibroblasts from patients affected by Pseudoxanthoma elasticum exhibit an altered PPi metabolism and are more responsive to pro-calcifying stimuli

Journal of Dermatological Science

Volumn 74, Issue 1, 2014, Pages 72-80

  Boraldi, Federica ^a   Annovi, Giulia ^a   Bartolomeo, Angelica ^a   Quaglino, Daniela ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Ectopic calcification; Fibroblasts; Pseudoxanthoma elasticum; Pyrophosphate

Indexed keywords

ALKALINE PHOSPHATASE ISOENZYME; PYROPHOSPHATE; TISSUE NONSPECIFIC ALKALINE PHOSPHATASE ISOZYME; UNCLASSIFIED DRUG; ALKALINE PHOSPHATASE; CALCIUM; CALCIUM BINDING PROTEIN; DIPHOSPHORIC ACID; MATRIX GLA PROTEIN; PRIMER DNA; PYROPHOSPHORIC ACID DERIVATIVE; SCLEROPROTEIN;

ADULT; ALPL GENE; ANALYTIC METHOD; ANKH GENE; ARTICLE; CALCIFICATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENPP1 GENE; ENVIRONMENTAL SCANNING ELECTRON MICROSCOPY; ENZYME ACTIVITY; FEMALE; FIBROBLAST CULTURE; GENE EXPRESSION; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; MICROSCOPY; MINERALIZATION; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOXANTHOMA ELASTICUM; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SKIN FIBROBLAST; SPECTROPHOTOMETRY; SPP1 GENE; WESTERN BLOTTING; CALCINOSIS; COMPLICATION; FIBROBLAST; METABOLISM; MIDDLE AGED; PATHOLOGY; SKIN; SPECTROMETRY; UPREGULATION;

ADULT; ALKALINE PHOSPHATASE; CALCINOSIS; CALCIUM; CALCIUM-BINDING PROTEINS; DIPHOSPHATES; DNA PRIMERS; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLASTS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MIDDLE AGED; PSEUDOXANTHOMA ELASTICUM; SKIN; SPECTROMETRY, X-RAY EMISSION; UP-REGULATION;

EID: 84895918999     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.12.008     Document Type: Article

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