Antidiabetic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in vivo in ob/ob mice

Phytomedicine

Volumn 21, Issue 11, 2014, Pages 1382-1389

  Moser, C ^a   Vickers, S P ^b   Brammer, R ^b   Cheetham, S C ^b   Drewe, J ^a  

^a Preclinical Research   (Switzerland)

^b RenaSci Ltd   (United Kingdom)

Author keywords

Cimicifuga racemosa Ze 450; Diabetes mellitus; In vitro; In vivo; ob ob mice

Indexed keywords

23 EPI 26 DEOXYACTEIN; CIMICIFUGA RACEMOSA EXTRACT; CIMIRACEMOSIDE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; METFORMIN; PROTOPINE; UNCLASSIFIED DRUG; ZE 450; 23-EPI-26-DEOXYACTEIN; ANTIDIABETIC AGENT; BENZOPHENANTHRIDINE DERIVATIVE; BERBERINE DERIVATIVE; CIMIRACEMOSIDE A; GLUCOSE BLOOD LEVEL; GLYCOSIDE; PLANT EXTRACT; SAPONIN; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; WEIGHT REDUCTION; ACTAEA; ANIMAL; BLOOD; BODY WEIGHT; CELL LINE; CHEMISTRY; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; GLUCOSE TOLERANCE TEST; METABOLISM; MOUSE MUTANT;

ANIMALIA; CIMICIFUGA RACEMOSA; MUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BENZOPHENANTHRIDINES; BERBERINE ALKALOIDS; BLOOD GLUCOSE; BODY WEIGHT; CELL LINE; CIMICIFUGA; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; GLUCOSE TOLERANCE TEST; GLYCOSIDES; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MALE; METFORMIN; MICE, OBESE; PLANT EXTRACTS; SAPONINS; TRITERPENES;

EID: 84906937711     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2014.06.002     Document Type: Article

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