Polyhexamethylene biguanide is a relevant sensitizer in wet wipes

Contact Dermatitis

Volumn 70, Issue 5, 2014, Pages 323-325

  Leysen, Julie ^a   Goossens, An ^b   Lambert, Julien ^a   Aerts, Olivier ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

allergic contact dermatitis; anogenital; cosmetics; polyaminopropylbiguanide; polyhexamethylene biguanide; polyhexanide; preservative; wipes

Indexed keywords

2 METHYL 4 ISOTHIAZOLIN 3 ONE; CASTOR OIL; CHLORHEXIDINE; CORTICOSTEROID; COSMETIC; LANOLIN ALCOHOL; METHYCHLOROISOTHIAZOLINONE; POLY(HEXAMETHYLENEBIGUANIDE); THIAZOLE DERIVATIVE; TOPICAL AGENT; UNCLASSIFIED DRUG; BIGUANIDE DERIVATIVE; DOMESTIC CHEMICAL;

ADULT; CASE REPORT; CORTICOSTEROID THERAPY; HUMAN; HYGIENE PRODUCT; MALE; OINTMENT; PAPULOVESICULAR RASH; PATCH TEST; SENSITIZATION; SHORT SURVEY; SKIN ALLERGY; WET WIPE; SKIN CARE;

ADULT; BIGUANIDES; HOUSEHOLD PRODUCTS; HUMANS; MALE; PATCH TESTS; SKIN CARE;

EID: 84906935156     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/cod.12208     Document Type: Short Survey

References (5)

1. Schnuch A, Geier J, Brasch J, et al. Polyhexamethylenebiguanide: a relevant contact allergen? Contact Dermatitis 2000: 42: 302-303.
2. Schnuch A, Geier J, Uter W, et al. The biocide polyhexamethylene biguanide remains an uncommon contact allergen. Contact Dermatitis 2007: 56: 235-239.
3. Kautz O, Schumann H, Degerbeck F, et al. Severe anaphylaxis to the antiseptic polyhexanide. Allergy 2010: 65: 1068-1070.
4. Ebo D G, Stevens W J, Bridts C H, et al. Contact-allergic dermatitis and life-threatening anaphylaxis to chlorhexidine. J Allergy Clin Immunol 1998: 101 (1 Pt 1): 128-129.
5. Sachs B, Fischer-Barth W, Erdmann S, et al. Anaphylaxis and toxic epidermal necrolysis or Stevens-Johnson syndrome after nonmucosal topical drug application: fact or fiction? Allergy 2007: 62: 877-883.