메뉴 건너뛰기




Volumn 119, Issue 1, 2014, Pages 7-15

Diffuse intrinsic pontine glioma: A reassessment

Author keywords

Brainstem biopsy; Brainstem glioma; Diffuse intrinsic pontine glioma; Epigenetics; Molecular signaling pathways

Indexed keywords

BRAIN BIOPSY; BRAIN STEM TUMOR; BRAINSTEM BIOPSY; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER EPIDEMIOLOGY; CANCER IMMUNOTHERAPY; CANCER PALLIATIVE THERAPY; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER RESEARCH; CHILDHOOD CANCER; DIFFERENTIAL DIAGNOSIS; DIFFUSION WEIGHTED IMAGING; GENE MUTATION; GENE SEQUENCE; HUMAN; MOLECULAR PATHOLOGY; MOLECULARLY TARGETED THERAPY; NEUROECTODERM TUMOR; NONHUMAN; PONTINE GLIOMA; REVIEW; SPECTROSCOPY; BIOPSY; BRAIN STEM NEOPLASMS; GLIOMA; PATHOLOGY; PONS; PROGNOSIS;

EID: 84906934474     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-014-1448-8     Document Type: Review
Times cited : (96)

References (60)
  • 1
    • 84906934229 scopus 로고
    • A case of pontine glioma, with special reference to the paths of gustatory sensation
    • Harris W (1926) A case of pontine glioma, with special reference to the paths of gustatory sensation. Proc R Soc Med 19:1-5
    • (1926) Proc R Soc Med , vol.19 , pp. 1-5
    • Harris, W.1
  • 2
    • 0014220308 scopus 로고
    • Pontine gliomas of childhood
    • Lassman LP, Arjona VE (1967) Pontine gliomas of childhood. Lancet 1:913-915
    • (1967) Lancet , vol.1 , pp. 913-915
    • Lassman, L.P.1    Arjona, V.E.2
  • 3
    • 33344464494 scopus 로고    scopus 로고
    • Diffuse brainstem glioma in children: Critical review of clinical trials
    • DOI 10.1016/S1470-2045(06)70615-5, PII S1470204506706155
    • Hargrave D, Bartels U, Bouffet E (2006) Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol 7:241-248 (Pubitemid 43286454)
    • (2006) Lancet Oncology , vol.7 , Issue.3 , pp. 241-248
    • Hargrave, D.1    Bartels, U.2    Bouffet, E.3
  • 7
    • 77950487385 scopus 로고    scopus 로고
    • Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets
    • Zarghooni M, Bartels U, Lee E, Buczkowicz P, Morrison A, Huang A, Bouffet E, Hawkins C (2010) Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets. J Clin Oncol 28:1337-1344
    • (2010) J Clin Oncol , vol.28 , pp. 1337-1344
    • Zarghooni, M.1    Bartels, U.2    Lee, E.3    Buczkowicz, P.4    Morrison, A.5    Huang, A.6    Bouffet, E.7    Hawkins, C.8
  • 9
    • 0031720453 scopus 로고    scopus 로고
    • Lower urinary tract dysfunction in children with central nervous system tumours
    • Soler D, Borzyskowski M (1998) Lower urinary tract dysfunction in children with central nervous system tumours. Arch Dis Child 79:344-347 (Pubitemid 28436088)
    • (1998) Archives of Disease in Childhood , vol.79 , Issue.4 , pp. 344-347
    • Soler, D.1    Borzyskowski, M.2
  • 10
    • 0022005530 scopus 로고
    • Resistive NMR of brain stem gliomas
    • DOI 10.1007/BF00342512
    • Zimmerman RA, Bilaniuk LT, Packer R, Sutton L, Samuel L, Johnson MH, Grossman RI, Goldberg HI (1985) Resistive NMR of brain stem gliomas. Neuroradiology 27:21-25 (Pubitemid 15179260)
    • (1985) Neuroradiology , vol.27 , Issue.1 , pp. 21-25
    • Zimmerman, R.A.1    Bilaniuk, L.T.2    Packer, R.3
  • 12
    • 0042320363 scopus 로고    scopus 로고
    • Clinicopathological study of diffuse type brainstem gliomas: Analysis of 40 autopsy cases
    • discussion 382
    • Yoshimura J, Onda K, Tanaka R, Takahashi H (2003) Clinicopathological study of diffuse type brainstem gliomas: analysis of 40 autopsy cases. Neurol Med Chir (Tokyo) 43:375-382; discussion 382
    • (2003) Neurol Med Chir (Tokyo) , vol.43 , pp. 375-382
    • Yoshimura, J.1    Onda, K.2    Tanaka, R.3    Takahashi, H.4
  • 14
    • 79851478828 scopus 로고    scopus 로고
    • Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: A report from the Pediatric Brain Tumor Consortium
    • Zukotynski KA, Fahey FH, Kocak M et al (2011) Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium. J Nucl Med 52:188-195
    • (2011) J Nucl Med , vol.52 , pp. 188-195
    • Zukotynski, K.A.1    Fahey, F.H.2    Kocak, M.3
  • 15
    • 0027519434 scopus 로고
    • Magnetic resonance scans should replace biopsies for the diagnosis of diffuse brain stem gliomas: A report from the Children's Cancer Group
    • discussion 1029-1030
    • Albright AL, Packer RJ, Zimmerman R, Rorke LB, Boyett J, Hammond GD (1993) Magnetic resonance scans should replace biopsies for the diagnosis of diffuse brain stem gliomas: a report from the Children's Cancer Group. Neurosurgery 33:1026-1029; discussion 1029-1030
    • (1993) Neurosurgery , vol.33 , pp. 1026-1029
    • Albright, A.L.1    Packer, R.J.2    Zimmerman, R.3    Rorke, L.B.4    Boyett, J.5    Hammond, G.D.6
  • 16
    • 84856812767 scopus 로고    scopus 로고
    • Favorable outcome with conservative treatment for children with low grade brainstem tumors
    • Fried I, Hawkins C, Scheinemann K et al (2012) Favorable outcome with conservative treatment for children with low grade brainstem tumors. Pediatr Blood Cancer 58:556-560
    • (2012) Pediatr Blood Cancer , vol.58 , pp. 556-560
    • Fried, I.1    Hawkins, C.2    Scheinemann, K.3
  • 17
    • 78651323482 scopus 로고    scopus 로고
    • Post mortem examinations in diffuse intrinsic pontine glioma: Challenges and chances
    • Angelini P, Hawkins C, Laperriere N, Bouffet E, Bartels U (2011) Post mortem examinations in diffuse intrinsic pontine glioma: challenges and chances. J Neurooncol 101:75-81
    • (2011) J Neurooncol , vol.101 , pp. 75-81
    • Angelini, P.1    Hawkins, C.2    Laperriere, N.3    Bouffet, E.4    Bartels, U.5
  • 18
    • 37549061811 scopus 로고    scopus 로고
    • Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): Report of the Head Start I and II experience
    • Fangusaro J, Finlay J, Sposto R et al (2008) Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): report of the Head Start I and II experience. Pediatr Blood Cancer 50:312-318
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 312-318
    • Fangusaro, J.1    Finlay, J.2    Sposto, R.3
  • 19
    • 77953577317 scopus 로고    scopus 로고
    • DTI fiber tracking to differentiate demyelinating diseases from diffuse brain stem glioma
    • Giussani C, Poliakov A, Ferri RT et al (2010) DTI fiber tracking to differentiate demyelinating diseases from diffuse brain stem glioma. Neuroimage 52:217-223
    • (2010) Neuroimage , vol.52 , pp. 217-223
    • Giussani, C.1    Poliakov, A.2    Ferri, R.T.3
  • 22
    • 0028064427 scopus 로고
    • Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy: A Childrens Cancer Group Phase I/II trial
    • DOI 10.1002/1097-0142(19940915)74:6<1827::AID-CNCR
    • Packer RJ, Boyett JM, Zimmerman RA, Albright AL, Kaplan AM, Rorke LB, Selch MT, Cherlow JM, Finlay JL, Wara WM (1994) Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy. A Childrens Cancer Group Phase I/II Trial. Cancer 74:1827-1834 (Pubitemid 24301840)
    • (1994) Cancer , vol.74 , Issue.6 , pp. 1827-1834
    • Packer, R.J.1    Boyett, J.M.2    Zimmerman, R.A.3    Albright, A.L.4    Kaplan, A.M.5    Rorke, L.B.6    Selch, M.T.7    Cherlow, J.M.8    Finlay, J.L.9    Wara, W.M.10
  • 23
    • 84872184811 scopus 로고    scopus 로고
    • Hypofractionation vs conventional radiation therapy for newly diagnosed diffuse intrinsic pontine glioma: A matched-cohort analysis
    • Janssens GO, Jansen MH, Lauwers SJ et al (2013) Hypofractionation vs conventional radiation therapy for newly diagnosed diffuse intrinsic pontine glioma: a matched-cohort analysis. Int J Radiat Oncol Biol Phys 85:315-320
    • (2013) Int J Radiat Oncol Biol Phys , vol.85 , pp. 315-320
    • Janssens, G.O.1    Jansen, M.H.2    Lauwers, S.J.3
  • 24
    • 0034142195 scopus 로고    scopus 로고
    • Radiotherapy followed by high dose busulfan and thiotepa: A prospective assessment of high dose chemotherapy in children with diffuse pontine gliomas
    • DOI 10.1002/(SICI)1097-0142(20000201)88:3<685::AID
    • Bouffet E, Raquin M, Doz F, Gentet JC, Rodary C, Demeocq F, Chastagner P, Lutz P, Hartmann O, Kalifa C (2000) Radiotherapy followed by high dose busulfan and thiotepa: a prospective assessment of high dose chemotherapy in children with diffuse pontine gliomas. Cancer 88:685-692 (Pubitemid 30056946)
    • (2000) Cancer , vol.88 , Issue.3 , pp. 685-692
    • Bouffet, E.1    Raquin, M.2    Doz, F.3    Gentet, J.-C.4    Rodary, C.5    Demeocq, F.6    Chastagner, P.7    Lutz, P.8    Hartmann, O.9    Kalifa, C.10
  • 25
    • 37549026208 scopus 로고    scopus 로고
    • Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: A Children's Oncology Group phase II study
    • Korones DN, Fisher PG, Kretschmar C, Zhou T, Chen Z, Kepner J, Freeman C (2008) Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine and oral VP-16: a Children's Oncology Group phase II study. Pediatr Blood Cancer 50:227-230
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 227-230
    • Korones, D.N.1    Fisher, P.G.2    Kretschmar, C.3    Zhou, T.4    Chen, Z.5    Kepner, J.6    Freeman, C.7
  • 26
    • 79955760460 scopus 로고    scopus 로고
    • Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: A report from the Children's Oncology Group
    • Cohen KJ, Heideman RL, Zhou T, Holmes EJ, Lavey RS, Bouffet E, Pollack IF (2011) Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group. Neuro Oncol 13:410-416
    • (2011) Neuro Oncol , vol.13 , pp. 410-416
    • Cohen, K.J.1    Heideman, R.L.2    Zhou, T.3    Holmes, E.J.4    Lavey, R.S.5    Bouffet, E.6    Pollack, I.F.7
  • 27
    • 79952149650 scopus 로고    scopus 로고
    • The addition of high-dose tamoxifen to standard radiotherapy does not improve the survival of patients with diffuse intrinsic pontine glioma
    • Michalski A, Bouffet E, Taylor RE, Hargrave D, Walker D, Picton S, Robinson K, Pizer B, Bujkiewicz S (2010) The addition of high-dose tamoxifen to standard radiotherapy does not improve the survival of patients with diffuse intrinsic pontine glioma. J Neurooncol 100:81-88
    • (2010) J Neurooncol , vol.100 , pp. 81-88
    • Michalski, A.1    Bouffet, E.2    Taylor, R.E.3    Hargrave, D.4    Walker, D.5    Picton, S.6    Robinson, K.7    Pizer, B.8    Bujkiewicz, S.9
  • 29
    • 84875745158 scopus 로고    scopus 로고
    • A multi-disciplinary consensus statement concerning surgical approaches to low-grade, high-grade astrocytomas and diffuse intrinsic pontine gliomas in childhood (CPN Paris 2011) using the Delphi method
    • CPN Paris 2011 Conference Consensus Group
    • Walker DA, Liu J, Kieran M, Jabado N, Picton S, Packer R, St Rose C, CPN Paris 2011 Conference Consensus Group (2011) A multi-disciplinary consensus statement concerning surgical approaches to low-grade, high-grade astrocytomas and diffuse intrinsic pontine gliomas in childhood (CPN Paris 2011) using the Delphi method. Neuro Oncol 15:462-468
    • (2011) Neuro Oncol , vol.15 , pp. 462-468
    • Walker, D.A.1    Liu, J.2    Kieran, M.3    Jabado, N.4    Picton, S.5    Packer, R.6    St Rose, C.7
  • 30
    • 84901676138 scopus 로고    scopus 로고
    • Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes
    • doi:10.1007/s00401-013-1218-2
    • Saratsis AM, Kambhampati M, Snyder K et al (2013) Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes. Acta Neuropathol (Berl). doi:10.1007/s00401-013-1218-2
    • (2013) Acta Neuropathol (Berl)
    • Saratsis, A.M.1    Kambhampati, M.2    Snyder, K.3
  • 31
    • 84862777348 scopus 로고    scopus 로고
    • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
    • Schwartzentruber J, Korshunov A, Liu X-Y et al (2012) Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482:226-231
    • (2012) Nature , vol.482 , pp. 226-231
    • Schwartzentruber, J.1    Korshunov, A.2    Liu, X.-Y.3
  • 32
    • 84865863019 scopus 로고    scopus 로고
    • K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
    • Khuong-Quang D-A, Buczkowicz P, Rakopoulos P et al (2012) K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol (Berl) 124:439-447
    • (2012) Acta Neuropathol (Berl) , vol.124 , pp. 439-447
    • Khuong-Quang, D.-A.1    Buczkowicz, P.2    Rakopoulos, P.3
  • 33
    • 84862777410 scopus 로고    scopus 로고
    • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
    • doi:10.1038/ng.1102
    • Wu G, Broniscer A, McEachron TA et al (2012) Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet. doi:10.1038/ng.1102
    • (2012) Nat Genet
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3
  • 35
    • 80054771090 scopus 로고    scopus 로고
    • Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma
    • Paugh BS, Broniscer A, Qu C et al (2011) Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J Clin Oncol 29:3999-4006
    • (2011) J Clin Oncol , vol.29 , pp. 3999-4006
    • Paugh, B.S.1    Broniscer, A.2    Qu, C.3
  • 40
    • 84864746573 scopus 로고    scopus 로고
    • A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers
    • Lee RS, Stewart C, Carter SL et al (2012) A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J Clin Invest 122:2983-2988
    • (2012) J Clin Invest , vol.122 , pp. 2983-2988
    • Lee, R.S.1    Stewart, C.2    Carter, S.L.3
  • 41
    • 84857527038 scopus 로고    scopus 로고
    • Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas
    • Puget S, Philippe C, Bax DA et al (2012) Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS One 7:e30313
    • (2012) PLoS One , vol.7
    • Puget, S.1    Philippe, C.2    Bax, D.A.3
  • 42
    • 77950232139 scopus 로고    scopus 로고
    • Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma
    • Becher OJ, Hambardzumyan D, Walker TR et al (2010) Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma. Cancer Res 70:2548-2557
    • (2010) Cancer Res , vol.70 , pp. 2548-2557
    • Becher, O.J.1    Hambardzumyan, D.2    Walker, T.R.3
  • 43
    • 77954387918 scopus 로고    scopus 로고
    • Glial progenitors in the brainstem give rise to malignant gliomas by platelet-derived growth factor stimulation
    • Masui K, Suzuki SO, Torisu R, Goldman JE, Canoll P, Iwaki T (2010) Glial progenitors in the brainstem give rise to malignant gliomas by platelet-derived growth factor stimulation. Glia 58:1050-1065
    • (2010) Glia , vol.58 , pp. 1050-1065
    • Masui, K.1    Suzuki, S.O.2    Torisu, R.3    Goldman, J.E.4    Canoll, P.5    Iwaki, T.6
  • 44
    • 79952717343 scopus 로고    scopus 로고
    • Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma
    • Monje M, Mitra SS, Freret ME et al (2011) Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proc Natl Acad Sci USA 108:4453-4458
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4453-4458
    • Monje, M.1    Mitra, S.S.2    Freret, M.E.3
  • 45
    • 84877605428 scopus 로고    scopus 로고
    • A phase I/II study of LDE225, a smoothened (Smo) antagonist, in pediatric patients with recurrent medulloblastoma (MB) or other solid tumors
    • 2012 ASCO Annual Meeting. abstr 9519
    • Geoerger B, Aerts I, Casanova M et al (2012) A phase I/II study of LDE225, a smoothened (Smo) antagonist, in pediatric patients with recurrent medulloblastoma (MB) or other solid tumors. In: 2012 ASCO Annual Meeting. J Clin Oncol 30:suppl; abstr 9519
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Geoerger, B.1    Aerts, I.2    Casanova, M.3
  • 47
    • 78149258374 scopus 로고    scopus 로고
    • Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma
    • Broniscer A, Baker JN, Tagen M et al (2010) Phase I study of vandetanib during and after radiotherapy in children with diffuse intrinsic pontine glioma. J Clin Oncol 28:4762-4768
    • (2010) J Clin Oncol , vol.28 , pp. 4762-4768
    • Broniscer, A.1    Baker, J.N.2    Tagen, M.3
  • 48
    • 79955773922 scopus 로고    scopus 로고
    • Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas
    • Haas-Kogan DA, Banerjee A, Poussaint TY et al (2011) Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas. Neuro Oncol 13:298-306
    • (2011) Neuro Oncol , vol.13 , pp. 298-306
    • Haas-Kogan, D.A.1    Banerjee, A.2    Poussaint, T.Y.3
  • 49
    • 77954596239 scopus 로고    scopus 로고
    • Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease
    • Paugh BS, Qu C, Jones C et al (2010) Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol 28:3061-3068
    • (2010) J Clin Oncol , vol.28 , pp. 3061-3068
    • Paugh, B.S.1    Qu, C.2    Jones, C.3
  • 51
    • 84861760527 scopus 로고    scopus 로고
    • Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors
    • Vivanco I, Robins HI, Rohle D et al (2012) Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer Discov 2:458-471
    • (2012) Cancer Discov , vol.2 , pp. 458-471
    • Vivanco, I.1    Robins, H.I.2    Rohle, D.3
  • 52
    • 84878991908 scopus 로고    scopus 로고
    • Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma
    • Broniscer A, Baker SD, Wetmore C et al (2013) Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma. Clin Cancer Res 19:3050-3058
    • (2013) Clin Cancer Res , vol.19 , pp. 3050-3058
    • Broniscer, A.1    Baker, S.D.2    Wetmore, C.3
  • 53
    • 84876915498 scopus 로고    scopus 로고
    • In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma
    • Veringa SJE, Biesmans D, van Vuurden DG et al (2013) In vitro drug response and efflux transporters associated with drug resistance in pediatric high grade glioma and diffuse intrinsic pontine glioma. PLoS One 8:e61512
    • (2013) PLoS One , vol.8
    • Veringa, S.J.E.1    Biesmans, D.2    Van Vuurden, D.G.3
  • 54
    • 84895442538 scopus 로고    scopus 로고
    • Magnetic resonance imaging properties of convective delivery in diffuse intrinsic pontine gliomas
    • doi:10.3171/2013.11.PEDS136
    • Chittiboina P, Heiss JD, Warren KE, Lonser RR (2014) Magnetic resonance imaging properties of convective delivery in diffuse intrinsic pontine gliomas. J Neurosurg Pediatr. doi:10.3171/2013.11.PEDS136
    • (2014) J Neurosurg Pediatr
    • Chittiboina, P.1    Heiss, J.D.2    Warren, K.E.3    Lonser, R.R.4
  • 55
    • 84939687483 scopus 로고
    • Adjuvant immunotherapy for malignant brain tumors in infants and children
    • Takakura K, Miki Y, Kubo O (1975) Adjuvant immunotherapy for malignant brain tumors in infants and children. Childs Brain 1:141-147
    • (1975) Childs Brain , vol.1 , pp. 141-147
    • Takakura, K.1    Miki, Y.2    Kubo, O.3
  • 56
    • 56549131425 scopus 로고    scopus 로고
    • Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma
    • Joshi BH, Puri RA, Leland P, Varricchio F, Gupta G, Kocak M, Gilbertson RJ, Puri RK (2008) Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma. Neuro Oncol 10:265-274
    • (2008) Neuro Oncol , vol.10 , pp. 265-274
    • Joshi, B.H.1    Puri, R.A.2    Leland, P.3    Varricchio, F.4    Gupta, G.5    Kocak, M.6    Gilbertson, R.J.7    Puri, R.K.8
  • 57
    • 84864051320 scopus 로고    scopus 로고
    • Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas
    • Li G, Mitra SS, Monje M, Henrich KN, Bangs CD, Nitta RT, Wong AJ (2012) Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas. J Neurooncol 108:395-402
    • (2012) J Neurooncol , vol.108 , pp. 395-402
    • Li, G.1    Mitra, S.S.2    Monje, M.3    Henrich, K.N.4    Bangs, C.D.5    Nitta, R.T.6    Wong, A.J.7
  • 60
    • 79951611374 scopus 로고    scopus 로고
    • Innovative therapies for children with cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors
    • Geoerger B, Hargrave D, Thomas F et al (2011) Innovative therapies for children with cancer pediatric phase I study of erlotinib in brainstem glioma and relapsing/refractory brain tumors. Neuro Oncol 13:109-118
    • (2011) Neuro Oncol , vol.13 , pp. 109-118
    • Geoerger, B.1    Hargrave, D.2    Thomas, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.