Comparative analysis of different enzyme immunoassays for assessment of phosphatidylserine-dependent antiprothrombin antibodies

Rheumatology International

Volumn 34, Issue 9, 2014, Pages 1225-1230

  Amengual, Olga ^a   Horita, Tetsuya ^a   Binder, Walter ^b   Norman, Gary L ^b   Shums, Zakera ^b   Kato, Masaru ^a   Otomo, Kotaro ^a   Fujieda, Yuichiro ^a   Oku, Kenji ^a   Bohgaki, Toshiyuki ^a   Yasuda, Shinsuke ^a   Atsumi, Tatsuya ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b INOVA DIAGNOSTICS INC   (United States)

Author keywords

Antiphospholipid antibodies; Antiphospholipid syndrome; Lupus anticoagulant; Thrombosis

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY; BIOLOGICAL MARKER; DIAGNOSTIC KIT; PHOSPHATIDYLSERINE; PROTHROMBIN;

ANTIBODY BLOOD LEVEL; ANTIPHOSPHOLIPID SYNDROME; ARTICLE; BLOOD SAMPLING; ELISA KIT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; ADULT; AGED; BLOOD; COMPARATIVE STUDY; DIAGNOSTIC KIT; EVALUATION STUDY; FEMALE; IMMUNOLOGY; MALE; MIDDLE AGED; OBSERVER VARIATION; PREDICTIVE VALUE; PROCEDURES; QUALITY CONTROL; REPRODUCIBILITY; STANDARDS; YOUNG ADULT;

ADULT; AGED; ANTIBODIES, ANTIPHOSPHOLIPID; ANTIPHOSPHOLIPID SYNDROME; BIOLOGICAL MARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MIDDLE AGED; OBSERVER VARIATION; PHOSPHATIDYLSERINES; PREDICTIVE VALUE OF TESTS; PROTHROMBIN; QUALITY CONTROL; REAGENT KITS, DIAGNOSTIC; REPRODUCIBILITY OF RESULTS; YOUNG ADULT;

EID: 84906933972     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-014-2951-0     Document Type: Article

References (20)

1. Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, Cervera R, Derksen RH, de Groot PG, Koike T, Meroni PL, Reber G, Shoenfeld Y, Tincani A, Vlachoyiannopoulos PG, Krilis SA (2006) International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 4:295-306
2. Amengual O, Atsumi T, Koike T (2003) Specificities, properties, and clinical significance of antiprothrombin antibodies. Arthritis Rheum 48:886-895 (Pubitemid 36418230)
3. Galli M (2000) Which antiphospholipid antibodies should be measured in the antiphospholipid syndrome? Haemostasis 30(Suppl 2):57-62
4. Bardin N, Alessi MC, Dignat-George F, Vague IJ, Sampol J, Harle JR, Sanmarco M (2007) Does the anti-prothrombin antibodies measurement provide additional information in patients with thrombosis? Immunobiology 212:557-565 (Pubitemid 47109157)
5. Pengo V, Denas G, Bison E, Banzato A, Jose SP, Gresele P, Marongiu F, Erba N, Veschi F, Ghirarduzzi A, De Candia E, Montaruli B, Marietta M, Testa S, Barcellona D, Tripodi A, Italian Federation of Thrombosis C (2010) Prevalence and significance of anti-prothrombin (aPT) antibodies in patients with Lupus Anticoagulant (LA). Thromb Res 126:150-153
6. Hoxha A, Ruffatti A, Pittoni M, Bontadi A, Tonello M, Salvan E, Plebani M, Punzi L (2012) The clinical significance of autoantibodies directed against prothrombin in primary antiphospholipid syndrome. Clin Chim Acta 413:911-913
7. Atsumi T, Ieko M, Bertolaccini ML, Ichikawa K, Tsutsumi A, Matsuura E, Koike T (2000) Association of autoantibodies against the phosphatidylserine- prothrombin complex with manifestations of the antiphospholipid syndrome and with the presence of lupus anticoagulant. Arthritis Rheum 43:1982-1993
8. Nojima J, Iwatani Y, Suehisa E, Kuratsune H, Kanakura Y (2006) The presence of anti-phosphatidylserine/prothrombin antibodies as risk factor for both arterial and venous thrombosis in patients with systemic lupus erythematosus. Haematologica 91:699-702 (Pubitemid 43799474)
9. Vlagea AD, Gil A, Cuesta MV, Arribas F, Diez J, Lavilla P, Pascual-Salcedo D (2012) Antiphosphatidylserine/prothrombin antibodies (aPS/PT) as potential markers of antiphospholipid syndrome. Clin Appl Thromb Hemost 19:289-296
10. Hoxha A, Ruffatti A, Tonello M, Bontadi A, Salvan E, Banzato A, Pengo V, Punzi L (2012) Antiphosphatidylserine/prothrombin antibodies in primary antiphospholipid syndrome. Lupus 21:787-789
11. Pregnolato F, Chighizola CB, Encabo S, Shums Z, Norman GL, Tripodi A, Chantarangkul V, Bertero T, De Micheli V, Borghi MO, Meroni PL (2013) Anti-phosphatidylserine/prothrombin antibodies: an additional diagnostic marker for APS? Immunol Res 56:432-438
12. Arvieux J, Darnige L, Caron C, Reber G, Bensa JC, Colomb MG (1995) Development of an ELISA for autoantibodies to prothrombin showing their prevalence in patients with lupus anticoagulant. Thromb Haemost 74:1120-1125
13. Atsumi T, Koike T (2010) Antiprothrombin antibody: why do we need more assays? Lupus 19:436-439
14. Bertolaccini ML, Atsumi T, Koike T, Hughes GR, Khamashta MA (2005) Antiprothrombin antibodies detected in two different assay systems. Prevalence and clinical significance in systemic lupus erythematosus. Thromb Haemost 93:289-297 (Pubitemid 40253734)
15. Jaskowski TD, Wilson AR, Hill HR, Branch WD, Tebo AE (2009) Autoantibodies against phosphatidylserine, prothrombin and phosphatidylserine- prothrombin complex: identical or distinct diagnostic tools for antiphospholipid syndrome? Clin Chim Acta 410:19-24
16. Sanfelippo M, Joshi A, Schwartz S, Meister J, Goldberg J (2013) Antibodies to phosphatidylserine/prothrombin complex in suspected antiphospholipid syndrome in the absence of antibodies to cardiolipin or β-2-glycoprotein I. Lupus 22:1349-1352
17. Bertolaccini ML, Amengual O, Atsumi T, Binder WL, de Laat B, Forastiero R, Kutteh WH, Lambert M, Matsubayashi H, Murthy V, Petri M, Rand JH, Sanmarco M, Tebo AE and Pierangeli SS (2011) 'Non-criteria' aPL tests: report of a task force and preconference workshop at the 13th International Congress on Antiphospholipid Antibodies, Galveston, TX, USA, April 2010. Lupus 20:191-205
18. Otomo K, Atsumi T, Amengual O, Fujieda Y, Kato M, Oku K, Horita T, Yasuda S, Koike T (2012) Efficacy of the antiphospholipid score for the diagnosis of antiphospholipid syndrome and its predictive value for thrombotic events. Arthritis Rheum 64:504-512
19. Sciascia S, Bertolaccini ML, Roccatello D, Khamashta MA (2013) Independent validation of the antiphospholipid score for the diagnosis of antiphospholipid syndrome. Ann Rheum Dis 72:142-143
20. Sciascia S, Sanna G, Murru V, Roccatello D, Khamashta MA, Bertolaccini ML (2013) GAPSS: the Global Anti-Phospholipid Syndrome Score. Rheumatology (Oxford) 52:1397-1403