-
1
-
-
2442718786
-
Increased airway epithelial Na1 absorption produces cystic fibrosis-like lung disease in mice
-
Mall M, Grubb BR, Harkema JR, O'Neal WK, Boucher RC. Increased airway epithelial Na1 absorption produces cystic fibrosis-like lung disease in mice. Nat Med 2004;10:487-493.
-
(2004)
Nat Med
, vol.10
, pp. 487-493
-
-
Mall, M.1
Grubb, B.R.2
Harkema, J.R.3
O'Neal, W.K.4
Boucher, R.C.5
-
2
-
-
84863476402
-
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
-
Pezzulo AA, Tang XX, Hoegger MJ, Alaiwa MH, Ramachandran S, Moninger TO, Karp PH, Wohlford-Lenane CL, Haagsman HP, van Eijk M, et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature 2012;487:109-113.
-
(2012)
Nature
, vol.487
, pp. 109-113
-
-
Pezzulo, A.A.1
Tang, X.X.2
Hoegger, M.J.3
Alaiwa, M.H.4
Ramachandran, S.5
Moninger, T.O.6
Karp, P.H.7
Wohlford-Lenane, C.L.8
Haagsman, H.P.9
Van Eijk, M.10
-
4
-
-
67650712233
-
Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening
-
Sly PD, Brennan S, Gangell C, de Klerk N, Murray C, Mott L, Stick SM, Robinson PJ, Robertson CF, Ranganathan SC; Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST-CF). Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. Am J Respir Crit Care Med 2009;180:146-152.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 146-152
-
-
Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST-CF)1
Sly, P.D.2
Brennan, S.3
Gangell, C.4
De Klerk, N.5
Murray, C.6
Mott, L.7
Stick, S.M.8
Robinson, P.J.9
Robertson, C.F.10
Ranganathan, S.C.11
-
5
-
-
84898994097
-
Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease
-
Wielpütz MO, Puderbach M, Kopp-Schneider A, Stahl M, Fritzsching E, Sommerburg O, Ley S, Sumkauskaite M, Biederer J, Kauczor HU, et al. Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease. Am J Respir Crit Care Med 2014;189:956-965.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 956-965
-
-
Wielpütz, M.O.1
Puderbach, M.2
Kopp-Schneider, A.3
Stahl, M.4
Fritzsching, E.5
Sommerburg, O.6
Ley, S.7
Sumkauskaite, M.8
Biederer, J.9
Kauczor, H.U.10
-
6
-
-
84878000440
-
Risk factors for bronchiectasis in children with cystic fibrosis
-
Sly PD, Gangell CL, Chen L, Ware RS, Ranganathan S, Mott LS, Murray CP, Stick SM; AREST CF Investigators. Risk factors for bronchiectasis in children with cystic fibrosis. N Engl J Med 2013;368:1963-1970.
-
(2013)
N Engl J Med
, vol.368
, pp. 1963-1970
-
-
Sly, P.D.1
Gangell, C.L.2
Chen, L.3
Ware, R.S.4
Ranganathan, S.5
Mott, L.S.6
Murray, C.P.7
Stick, S.M.8
-
7
-
-
84868296268
-
Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis
-
Sagel SD, Wagner BD, Anthony MM, Emmett P, Zemanick ET. Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis. Am J Respir Crit Care Med 2012;186:857-865.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 857-865
-
-
Sagel, S.D.1
Wagner, B.D.2
Anthony, M.M.3
Emmett, P.4
Zemanick, E.T.5
-
8
-
-
84899791723
-
Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease
-
Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, et al. Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease. Am J Respir Crit Care Med 2014;189:1082-1092.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 1082-1092
-
-
Gehrig, S.1
Duerr, J.2
Weitnauer, M.3
Wagner, C.J.4
Graeber, S.Y.5
Schatterny, J.6
Hirtz, S.7
Belaaouaj, A.8
Dalpke, A.H.9
Schultz, C.10
-
9
-
-
0037768888
-
Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins
-
Taggart CC, Greene CM, Smith SG, Levine RL, McCray PB Jr, O'Neill S, McElvaney NG. Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins. J Immunol 2003;171:931-937.
-
(2003)
J Immunol
, vol.171
, pp. 931-937
-
-
Taggart, C.C.1
Greene, C.M.2
Smith, S.G.3
LeVine, R.L.4
McCray, P.B.5
O'Neill, S.6
McElvaney, N.G.7
-
10
-
-
80053063761
-
The role of matrix metalloproteinases in cystic fibrosis lung disease
-
Gaggar A, Hector A, Bratcher PE, Mall MA, Griese M, Hartl D. The role of matrix metalloproteinases in cystic fibrosis lung disease. Eur Respir J 2011;38:721-727.
-
(2011)
Eur Respir J
, vol.38
, pp. 721-727
-
-
Gaggar, A.1
Hector, A.2
Bratcher, P.E.3
Mall, M.A.4
Griese, M.5
Hartl, D.6
-
11
-
-
84938272261
-
Airway mucus obstruction triggers macrophage activation and MMP12-dependent emphysema
-
(In press)
-
Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, et al. Airway mucus obstruction triggers macrophage activation and MMP12-dependent emphysema. Am J Respir Cell Mol Biol (In press)
-
Am J Respir Cell Mol Biol
-
-
Trojanek, J.B.1
Cobos-Correa, A.2
Diemer, S.3
Kormann, M.4
Schubert, S.C.5
Zhou-Suckow, Z.6
Agrawal, R.7
Duerr, J.8
Wagner, C.J.9
Schatterny, J.10
-
12
-
-
84906922269
-
MiR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production
-
Weldon S, McNally P, McAuley DF, Oglesby IK, Wohlford-Lenane CL, Bartlett JA, Scott CJ, McElvaney NG, MGreene C, McCray PB Jr, et al. miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production. Am J Respir Crit Care Med 2014;190:165-174.
-
(2014)
Am J Respir Crit Care Med
, vol.190
, pp. 165-174
-
-
Weldon, S.1
McNally, P.2
McAuley, D.F.3
Oglesby, I.K.4
Wohlford-Lenane, C.L.5
Bartlett, J.A.6
Scott, C.J.7
McElvaney, N.G.8
MGreene, C.9
McCray, P.B.10
-
13
-
-
0037805704
-
Lysosomal cysteine proteases regulate antigen presentation
-
Honey K, Rudensky AY. Lysosomal cysteine proteases regulate antigen presentation. Nat Rev Immunol 2003;3:472-482.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 472-482
-
-
Honey, K.1
Rudensky, A.Y.2
-
14
-
-
0026630108
-
Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease
-
Shi GP, Munger JS, Meara JP, Rich DH, Chapman HA. Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease. J Biol Chem 1992;267:7258-7262.
-
(1992)
J Biol Chem
, vol.267
, pp. 7258-7262
-
-
Shi, G.P.1
Munger, J.S.2
Meara, J.P.3
Rich, D.H.4
Chapman, H.A.5
-
15
-
-
84865176379
-
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator
-
Ramachandran S, Karp PH, Jiang P, Ostedgaard LS, Walz AE, Fisher JT, Keshavjee S, Lennox KA, Jacobi AM, Rose SD, et al. A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci USA 2012;109:13362-13367.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 13362-13367
-
-
Ramachandran, S.1
Karp, P.H.2
Jiang, P.3
Ostedgaard, L.S.4
Walz, A.E.5
Fisher, J.T.6
Keshavjee, S.7
Lennox, K.A.8
Jacobi, A.M.9
Rose, S.D.10
-
16
-
-
84862663742
-
Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters
-
Gehrig S, Mall MA, Schultz C. Spatially resolved monitoring of neutrophil elastase activity with ratiometric fluorescent reporters. Angew Chem Int Ed Engl 2012;51:6258-6261.
-
(2012)
Angew Chem Int Ed Engl
, vol.51
, pp. 6258-6261
-
-
Gehrig, S.1
Mall, M.A.2
Schultz, C.3
-
17
-
-
69249231952
-
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation
-
Cobos-Correa A, Trojanek JB, Diemer S, Mall MA, Schultz C. Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation. Nat Chem Biol 2009;5:628-630.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 628-630
-
-
Cobos-Correa, A.1
Trojanek, J.B.2
Diemer, S.3
Mall, M.A.4
Schultz, C.5
-
18
-
-
84866740546
-
Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S
-
Haerteis S, Krappitz M, Bertog M, Krappitz A, Baraznenok V, Henderson I, Lindström E, Murphy JE, Bunnett NW, Korbmacher C. Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S. Pflugers Arch 2012;464:353-365.
-
(2012)
Pflugers Arch
, vol.464
, pp. 353-365
-
-
Haerteis, S.1
Krappitz, M.2
Bertog, M.3
Krappitz, A.4
Baraznenok, V.5
Henderson, I.6
Lindström, E.7
Murphy, J.E.8
Bunnett, N.W.9
Korbmacher, C.10
-
19
-
-
84866097633
-
Personalized medicine in cystic fibrosis: Dawning of a new era
-
Clancy JP, Jain M. Personalized medicine in cystic fibrosis: dawning of a new era. Am J Respir Crit Care Med 2012;186:593-597.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 593-597
-
-
Clancy, J.P.1
Jain, M.2
|