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Volumn 201, Issue , 2014, Pages 207-214

Cabozantinib: A MET, RET, and VEGFR2 tyrosine kinase inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

CABOZANTINIB; PLACEBO; PROTEIN RET; SCATTER FACTOR RECEPTOR; VASCULOTROPIN RECEPTOR 2; ANILIDE; ANTINEOPLASTIC AGENT; MET PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; RET PROTEIN, HUMAN; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, HUMAN; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2, HUMAN;

EID: 84906924507     PISSN: 00800015     EISSN: 21976767     Source Type: Book Series    
DOI: 10.1007/978-3-642-54490-3_12     Document Type: Article
Times cited : (66)

References (19)
  • 1
    • 38049150665 scopus 로고    scopus 로고
    • MET amplification occurs with or without T790 M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
    • Bean J et al (2007) MET amplification occurs with or without T790 M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci USA 104(52): 20932-20937.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.52 , pp. 20932-20937
    • Bean, J.1
  • 2
    • 0026722243 scopus 로고
    • Hepatocyte growth-factor is a potent angiogenic factor which stimulates endothelial-cell motility and growth
    • Bussolino F et al (1992) Hepatocyte growth-factor is a potent angiogenic factor which stimulates endothelial-cell motility and growth. J Cell Biol 119(3): 629-641.
    • (1992) J Cell Biol , vol.119 , Issue.3 , pp. 629-641
    • Bussolino, F.1
  • 3
    • 0028946604 scopus 로고
    • Overexpression and amplification of the Met/Hgf receptor gene during the progression of colorectal-cancer
    • Direnzo MF et al (1995) Overexpression and amplification of the Met/Hgf receptor gene during the progression of colorectal-cancer. Clin Cancer Res 1(2): 147-154.
    • (1995) Clin Cancer Res , vol.1 , Issue.2 , pp. 147-154
    • Direnzo, M.F.1
  • 4
    • 0025075114 scopus 로고
    • Gene amplification in gastric and esophageal adenocarcinomas
    • Houldsworth J et al (1990) Gene amplification in gastric and esophageal adenocarcinomas. Cancer Res 50(19): 6417-6422.
    • (1990) Cancer Res , vol.50 , Issue.19 , pp. 6417-6422
    • Houldsworth, J.1
  • 5
    • 79959936054 scopus 로고    scopus 로고
    • Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer
    • Kurzrock R et al (2011) Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer. J Clin Oncol 29(19): 2660-2666.
    • (2011) J Clin Oncol , vol.29 , Issue.19 , pp. 2660-2666
    • Kurzrock, R.1
  • 6
    • 0035023230 scopus 로고    scopus 로고
    • Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases
    • Matsumoto K, Nakamura T (2001) Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Int 59(6): 2023-2038.
    • (2001) Kidney Int , vol.59 , Issue.6 , pp. 2023-2038
    • Matsumoto, K.1    Nakamura, T.2
  • 8
    • 0035070420 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy
    • Mizuno S, Matsumoto K, Nakamura T (2001) Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney Int 59(4): 1304-1314.
    • (2001) Kidney Int , vol.59 , Issue.4 , pp. 1304-1314
    • Mizuno, S.1    Matsumoto, K.2    Nakamura, T.3
  • 9
    • 84867406340 scopus 로고    scopus 로고
    • Combined therapy with mutant-selective EGFR inhibitor and met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer
    • Nakagawa T et al (2012) Combined therapy with mutant-selective EGFR inhibitor and met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. Mol Cancer Ther 11(10): 2149-2157.
    • (2012) Mol Cancer Ther , vol.11 , Issue.10 , pp. 2149-2157
    • Nakagawa, T.1
  • 10
    • 17344381429 scopus 로고    scopus 로고
    • Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
    • Schmidt L et al (1997) Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 16(1): 68-73.
    • (1997) Nat Genet , vol.16 , Issue.1 , pp. 68-73
    • Schmidt, L.1
  • 11
    • 84867754481 scopus 로고    scopus 로고
    • An international, double-blind, randomized, placebo-controlled phase III trial (EXAM) of cabozantinib (XL184) in medullary thyroid carcinoma (MTC) patients (pts) with documented RECIST progression at baseline
    • Schoffski P et al (2012) An international, double-blind, randomized, placebo-controlled phase III trial (EXAM) of cabozantinib (XL184) in medullary thyroid carcinoma (MTC) patients (pts) with documented RECIST progression at baseline. J Clin Oncol 30(15).
    • (2012) J Clin Oncol , vol.30 , Issue.15
    • Schoffski, P.1
  • 12
    • 84863704553 scopus 로고    scopus 로고
    • Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors
    • Sennino B et al (2012) Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors. Cancer Discov 2(3): 270-287.
    • (2012) Cancer Discov , vol.2 , Issue.3 , pp. 270-287
    • Sennino, B.1
  • 13
    • 7244229599 scopus 로고    scopus 로고
    • Microarray analysis of progression to reduced prostate cancer androgen dependence: Studies in unique models contrasts early and late molecular events
    • Sirotnak FM et al (2004) Microarray analysis of progression to reduced prostate cancer androgen dependence: studies in unique models contrasts early and late molecular events. Mol Carcinog 41(3): 150-163.
    • (2004) Mol Carcinog , vol.41 , Issue.3 , pp. 150-163
    • Sirotnak, F.M.1
  • 14
    • 84874787799 scopus 로고    scopus 로고
    • Cabozantinib in patients with advanced prostate cancer: Results of a phase II randomized discontinuation trial
    • Smith DC et al (2013) Cabozantinib in patients with advanced prostate cancer: results of a phase II randomized discontinuation trial. J Clin Oncol 31(4): 412-419.
    • (2013) J Clin Oncol , vol.31 , Issue.4 , pp. 412-419
    • Smith, D.C.1
  • 15
    • 0025828180 scopus 로고
    • The Tpr-Met oncogenic rearrangement is present and expressed in human gastric-carcinoma and precursor lesions
    • Soman NR et al (1991) The Tpr-Met oncogenic rearrangement is present and expressed in human gastric-carcinoma and precursor lesions. Proc Natl Acad Sci USA 88(11): 4892-4896.
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.11 , pp. 4892-4896
    • Soman, N.R.1
  • 16
    • 0029973125 scopus 로고    scopus 로고
    • Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development
    • Takayama H et al (1996) Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development. Proc Natl Acad Sci USA 93(12): 5866-5871.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.12 , pp. 5866-5871
    • Takayama, H.1
  • 17
    • 0036551486 scopus 로고    scopus 로고
    • Scatter-factor and semaphorin receptors: Cell signalling for invasive growth
    • Trusolino L, Comoglio PM (2002) Scatter-factor and semaphorin receptors: cell signalling for invasive growth. Nat Rev Cancer 2(4): 289-300.
    • (2002) Nat Rev Cancer , vol.2 , Issue.4 , pp. 289-300
    • Trusolino, L.1    Comoglio, P.M.2
  • 18
    • 33847057016 scopus 로고    scopus 로고
    • The androgen receptor negatively regulates the expression of c-Met: Implications for a novel mechanism of prostate cancer progression
    • Verras M et al (2007) The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression. Cancer Res 67(3): 967-975.
    • (2007) Cancer Res , vol.67 , Issue.3 , pp. 967-975
    • Verras, M.1
  • 19
    • 83355166909 scopus 로고    scopus 로고
    • Cabozantinib (XL184), a Novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth
    • Yakes FM et al (2011) Cabozantinib (XL184), a Novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol Cancer Ther 10(12): 2298-2308.
    • (2011) Mol Cancer Ther , vol.10 , Issue.12 , pp. 2298-2308
    • Yakes, F.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.