Antidepressant-like effects of auraptenol in mice

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Gu, Xiaosu ^a,b   Zhou, Yong ^c   Wu, Xiaomei ^b   Wang, Fen ^a   Zhang, Cai Yi ^a   Du, Chenchen ^a   Shen, Lihua ^b   Chen, Xiang ^b   Shi, Jiansheng ^b   Liu, Chunfeng ^a   Ke, Kaifu ^b  

^a SOOCHOW UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

^c First People's Hospital of Nantong   (China)

Author keywords

[No Author keywords available]

Indexed keywords

N-(2-(4-(2-METHOXYPHENYL)-1-PIPERAZINYL)ETHYL)-N-(2-PYRIDINYL)CYCLOHEXANECARBOXAMIDE; ANTIDEPRESSANT AGENT; AURAPTENOL; COUMARIN DERIVATIVE; HERBACEOUS AGENT; N (2 (4 (2 METHOXYPHENYL) 1 PIPERAZINYL)ETHYL) N (2 PYRIDINYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN 1 ANTAGONIST; SEROTONIN 1 RECEPTOR;

ANGELICA; ANIMAL; ANIMAL BEHAVIOR; ARTICLE; C57BL MOUSE; CHEMISTRY; DEPRESSION; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; IMMOBILIZATION; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOTOR ACTIVITY; MOUSE; PATHOPHYSIOLOGY; PHYTOTHERAPY; PSYCHOLOGICAL ASPECT; SWIMMING;

ANGELICA; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; COUMARINS; DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; HINDLIMB SUSPENSION; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PHYTOTHERAPY; PIPERAZINES; PYRIDINES; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SWIMMING;

EID: 84906911061     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep04433     Document Type: Article

References (15)

1. Nemeroff, C. B. The burden of severe depression: a review of diagnostic challenges and treatment alternatives. J. Psychiatr. Res. 41, 189-206 (2007).
2. Lai, J. S. et al. A systematic review and meta-analysis of dietary patterns and depression in community-dwelling adults. Am. J. Clin. Nutr. 99, 181-197 (2014).
3. Thachil, A. F., Mohan, R. & Bhugra, D. The evidence base of complementary and alternative therapies in depression. J. Affect. Disord. 97, 23-35 (2007).
4. Li, H., Dai, Y., Zhang, H. & Xie, C. [Pharmacological studies on the Chinese drug radix Angelicae dahuricae]. Zhongguo Zhong Yao Za Zhi 16, 560-562 (1991).
5. Nie, H. & Shen, Y. J. [Effect of essential oil of Radix Angelicae Dahuricae on betaendorphin, ACTH, NO and proopiomelanocortin of pain model rats]. Zhongguo Zhong Yao Za Zhi 27, 690-693 (2002).
6. Yuan, C. S. et al. Effects of Corydalis yanhusuo and Angelicae dahuricae on cold pressor-induced pain in humans: a controlled trial. J. Clin. Pharmacol. 44, 1323-1327 (2004).
7. Xie, Y., Zhao, W., Zhou, T., Fan, G. &Wu, Y. An efficient strategy based on MAE, HPLC-DAD-ESI-MS/MS and 2D-prep-HPLC-DAD for the rapid extraction, separation, identification and purification of five active coumarin components from Radix Angelicae Dahuricae. Phytochem. Anal. 21, 473-482 (2010).
8. Porsolt, R. D., Le Pichon, M.&Jalfre, M. Depression: a new animal model sensitive to antidepressant treatments. Nature 266, 730-732 (1977).
9. Porsolt, R. D., Anton, G., Blavet, N. & Jalfre, M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur. J. Pharmacol. 47, 379-391 (1978).
10. Steru, L., Chermat, R., Thierry, B. & Simon, P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology (Berl) 85, 367-370 (1985).
11. Li, J. X., Han, R., Deng, Y. P., Chen, S. Q. & Liang, J. H. Different effects of valproate on methamphetamine- and cocaine-induced behavioral sensitization in mice. Behav. Brain Res. 161, 125-132 (2005).
12. Garcia, R. Stress, metaplasticity, and antidepressants. Curr. Mol. Med. 2, 629-638 (2002).
13. Machado, D. G. et al. Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: involvement of the monoaminergic system. Prog. Neuropsychopharmacol. Biol. Psychiatry 33, 642-650 (2009).
14. Celada, P., Bortolozzi, A. & Artigas, F. Serotonin 5-HT1A receptors as targets for agents to treat psychiatric disorders: rationale and current status of research. CNS Drugs 27, 703-716 (2013).
15. Koek, W. et al. 5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential. Eur. J. Pharmacol. 420, 103-112 (2001).