An efficient strategy based on MAE, HPLC-DAD-ESI-MS/MS and 2D-prep-HPLC-DAD for the rapid extraction, separation, identification and purification of five active coumarin components from radix angelicae dahuricae

Phytochemical Analysis

Volumn 21, Issue 5, 2010, Pages 473-482

  Xie, Ying ^a,b   Zhao, Weiquan ^a,b   Zhou, Tingting ^a,b   Fan, Guorong ^a,b   Wu, Yutian ^a,b  

^a Second Military University   (China)

^b SHANGHAI KEY LABORATORY FOR PHARMACEUTICAL METABOLITE RESEARCH   (China)

Author keywords

Coumarins; High performance liquid chromatography diode array detection electrospray ionisation tandem mass spectrometry; Microwave assisted extraction; Radix angelicae dahuricae; Two dimensional preparative liquid chromatography

Indexed keywords

DIAGNOSIS; DIODES; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; PURIFICATION;

COUMARIN; ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-DIODE ARRAY DETECTION-ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-DIODE ARRAY DETECTIONS; MICROWAVE-ASSISTED EXTRACTION; PREPARATIVE LIQUID CHROMATOGRAPHY; RADIX ANGELICAE; RADIX ANGELICAE DAHURICAE; TWO-DIMENSIONAL; TWO-DIMENSIONAL PREPARATIVE LIQUID CHROMATOGRAPHY;

MASS SPECTROMETRY;

8 GERANOXY 5 METHOXYPSORALEN; 8 GERANYLOXYPSORALEN; ANGELICA ROOT EXTRACT; ANGELICIN; AURAPTENOL; COUMARIN DERIVATIVE; MONOMER; OSTHENOL; OXYPEUCEDANIN HYDRATE; PENTOSALEN; PIMPINELLIN; SCOPOLETIN; UNCLASSIFIED DRUG; XANTHOTOXOL;

ARTICLE; CHINESE MEDICINE; DIODE ARRAY DETECTION; DRUG ANALYSIS; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PURIFICATION; DRUG PURITY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MICROWAVE ASSISTED EXTRACTION; NONHUMAN; TANDEM MASS SPECTROMETRY;

EID: 77958092114     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.1222     Document Type: Article

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