Motor variability arises from a slow random walk in neural state

Journal of Neuroscience

Volumn 34, Issue 36, 2014, Pages 12071-12080

  Chaisanguanthum, Kris S ^a,b   Shen, Helen H ^a   Sabes, Philip N ^a,b  

^a Center for Integrative Neuroscience Department of Physiology   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; ARM; BASEBALL; DATA INTERPRETATION, STATISTICAL; HUMANS; MACACA; MALE; MOTOR CORTEX; MOVEMENT; NEURONS;

EID: 84906901937     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3001-13.2014     Document Type: Article

References (29)

1. Albert J (2010) Baseball data at season, play-by-play, and pitch-by-pitch levels. J Stat Educ 18:3.
2. Arieli A, Sterkin A, Grinvald A, Aertsen A (1996) Dynamics of ongoing activity: explanation of the large variability in evoked cortical responses. Science 273:1868-1871. Medline
3. Carmena JM, Lebedev MA, Henriquez CS, Nicolelis MAL (2005) Stable ensemble performance with single-neuron variability during reaching movements in primates. J Neurosci 25:10712-10716. CrossRef Medline
4. Cheng S, Sabes PN (2006) Modeling sensorimotor learning with dynamical systems. Neural Comput 18:760-793. CrossRef Medline
5. Cheng S, Sabes PN (2007) Calibration of visually guided reaching is driven by error-corrective learning and internal dynamics. J Neurophysiol 97: 3057-3069. CrossRef Medline
6. Chestek CA, Batista AP, Santhanam G, Yu BM, Afshar A, Cunningham JP, Gilja V, Ryu SI, Churchland MM, Shenoy KV (2007) Single-neuron stability during repeated reaching in macaque premotor cortex. J Neurosci 27:10742-10750. CrossRef Medline
7. Churchland MM, Afshar A, Shenoy KV (2006) A central source of movement variability. Neuron 52:1085-1096. CrossRef Medline
8. Faisal AA, Selen LP, Wolpert DM (2008) Noise in the nervous system. Nat Rev Neurosci 9:292-303. CrossRef Medline
9. Fraser GW, Schwartz AB (2012) Recording from the same neurons chronically in motor cortex. J Neurophysiol 107:1970-1978. CrossRef Medline
10. Georgopoulos AP, Kalaska JF, Massey JT (1981) Spatial trajectories and reaction times of aimed movements: effects of practice, uncertainty and change in target location. J Neurophysiol 46:725-743. Medline
11. Georgopoulos AP, Schwartz AB, Kettner RE (1986) Neuronal population coding of movement direction. Science 223:1416-1419. CrossRef Medline
12. Harris CM, Wolpert DM (1998) Signal-dependent noise determines motor planning. Nature 394:780-784. CrossRef Medline
13. Huang X, Lisberger SG (2009) Noise correlations in cortical area MT and their potential impact on trial-by-trial variation in the direction and speed of smooth-pursuit eye movements. J Neurophysiol 101:3012-3030. CrossRef Medline
14. Izawa J, Shadmehr R (2011) Learning from sensory and reward prediction errors during motor adaptation. PLoS Comput Biol 7:e1002012. CrossRef Medline
15. Lee D, Port NL, Kruse W, Georgopoulos AP (1998) Variability and correlated noise in the discharge of neurons in motor and parietal areas of the primate cortex. J Neurosci 18:1161-1170. Medline
16. Maynard EM, Nordhausen CT, Normann RA (1997) The Utah Intracortical Electrode Array: a recording structure for potential brain-computer interfaces. Electroencephalogr Clin Neurophysiol 102:228-239. CrossRef Medline
17. McGuire LM, Sabes PN (2011) Heterogeneous representations in the superior parietal lobule are common across reaches to visual and proprioceptivetargets. J Neurosci 31:6661- 6673. CrossRef Medline
18. Osborne LC, Lisberger SG, Bialek W (2005) A sensory source for motor variation. Nature 437:412-416. CrossRef Medline
19. Riehle A, Requin J (1993) The predictive value for performance speed of preparatory changes in neuronal activity of the monkey motor and premotor cortex. Behav Brain Res 53:35-49. CrossRef Medline
20. Rokni U, Richardson AG, Bizzi E, Seung HS (2007) Motor learning with unstable neural representations. Neuron 54:653-666. CrossRef Medline
21. Shmuelof L, Huang VS, Haith AM, Delnicki RJ, Mazzoni P, Krakauer JW (2012) Overcoming motor "forgetting" through reinforcement of learned actions. J Neurosci 32:14617-14621. CrossRef Medline
22. Smith MA, Ghazizadeh A, Shadmehr R (2006) Interacting adaptive processes with different timescales underlie short-term motor learning. PLoS Biol 4:e179. CrossRef Medline
23. Stevenson IH, Cherian A, London BM, Sachs NA, Lindberg E, Reimer J, Slutzky MW, Hatsopoulos NG, Miller LE, Kording KP (2011) Statistical assessment of the stability of neural movement representatinos. J Neurophysiol 106:764-774. CrossRef Medline
24. Thrun, S (1992) The role of exploration in learning control. In: Handbook for intelligent control: neural, fuzzy and adaptive approaches (White DA, Sofge DA, eds). Florence, KY: Van Nostrand Reinhold.
25. Todorov E, Jordan MI (2002) Optimal feedback control as a theory of motor coordination. Nat Neurosci 5:1226-1235. CrossRef Medline
26. van Beers RJ (2009) Motor learning is optimally tuned to the properties of motor noise. Neuron 63:406-417. CrossRef Medline
27. van Beers RJ, Brenner E, Smeets JB (2013) Random walk of motor planning in task-irrelevant dimensions. J Neurophysiol 109:969-977. CrossRef Medline
28. Verstynen T, Sabes PN (2011) How each movement changes the next: an experimental and theoretical study of fast adaptive priors in reaching. J Neurosci 31:10050-10059. CrossRef Medline
29. Xu-Wilson M, Zee DS, Shadmehr R (2009) The intrinsic value of visual information affects saccade velocities. Exp Brain Res 196:475-481. CrossRef Medline