Anillin interacts with microtubules and is part of the astral pathway that defines cortical domains

Journal of Cell Science

Volumn 127, Issue 17, 2014, Pages 3699-3710

  Triplet, Chloe van Oostende ^a   Garcia, Melina Jaramillo ^a   Bik, Husni Haji ^a   Beaudet, Daniel ^a   Piekny, Alisa ^a  

^a Dept of Electrical and Computer Engineering   (Canada)

Author keywords

Cytokinesis; Cytoskeleton; Polarity

Indexed keywords

ANILLIN; CONTRACTILE PROTEIN; MYOSIN;

CELL LINE; CELL POLARITY; CYTOKINESIS; CYTOSKELETON; GENETICS; HUMAN; METABOLISM; MICROTUBULE; PHYSIOLOGY; SPINDLE APPARATUS;

CELL LINE; CELL POLARITY; CONTRACTILE PROTEINS; CYTOKINESIS; CYTOSKELETON; HUMANS; MICROTUBULES; MYOSINS; SPINDLE APPARATUS;

EID: 84906860882     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.147504     Document Type: Article

References (44)

1. Bement, W. M., Benink, H. A. and von Dassow, G. (2005). A microtubuledependent zone of active RhoA during cleavage plane specification. J. Cell Biol 170, 91-101
2. Birkenfeld, J., Nalbant, P., Bohl, B. P., Pertz, O., Hahn, K. M. and Bokoch, G. M. (2007). GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. Dev. Cell 12, 699-712
3. Bringmann, H. and Hyman, A. A. (2005). A cytokinesis furrow is positioned by two consecutive signals. Nature 436, 731-734
4. Bringmann, H., Cowan, C. R., Kong, J. and Hyman, A. A. (2007). LET-99, GOA-1/GPA-16, and GPR-1/2 are required for aster-positioned cytokinesis. Curr. Biol 17, 185-191
5. Canman, J. C., Hoffman, D. B. and Salmon, E. D. (2000). The role of pre- and post-anaphase microtubules in the cytokinesis phase of the cell cycle. Curr Biol. 10, 611-614
6. Canman, J. C., Cameron, L. A., Maddox, P. S., Straight, A., Tirnauer, J. S., Mitchison, T. J., Fang, G., Kapoor, T. M. and Salmon, E. D. (2003) Determining the position of the cell division plane. Nature 424, 1074-1078
7. Carmena, M., Wheelock, M., Funabiki, H. and Earnshaw, W. C. (2012). The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat. Rev. Mol. Cell Biol. 13, 789-803
8. Chang, Y. C., Nalbant, P., Birkenfeld, J., Chang, Z. F. and Bokoch, G. M (2008). GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA. Mol. Biol. Cell 19, 2147-2153
9. D'Avino, P. P., Takeda, T., Capalbo, L., Zhang, W., Lilley, K. S., Laue, E. D. and Glover, D. M. (2008). Interaction between Anillin and RacGAP50C connects the actomyosin contractile ring with spindle microtubules at the cell division site J. Cell Sci. 121, 1151-1158
10. Dechant, R. and Glotzer, M. (2003). Centrosome separation and central spindle assembly act in redundant pathways that regulate microtubule density and trigger cleavage furrow formation. Dev. Cell 4, 333-344
11. Foe, V. E. and von Dassow, G. (2008). Stable and dynamic microtubules coordinately shape the myosin activation zone during cytokinetic furrow formation. J. Cell Biol. 183, 457-470
12. Frenette, P., Haines, E., Loloyan, M., Kinal, M., Pakarian, P. and Piekny, A (2012). An anillin-Ect2 complex stabilizes central spindle microtubules at the cortex during cytokinesis. PLoS ONE 7, e34888
13. Glotzer, M. (2009). The 3Ms of central spindle assembly: microtubules, motors and MAPs. Nat. Rev. Mol. Cell Biol. 10, 9-20
14. Green, R. A., Paluch, E. and Oegema, K. (2012). Cytokinesis in animal cells Annu. Rev. Cell Dev. Biol. 28, 29-58
15. Gregory, S. L., Ebrahimi, S., Milverton, J., Jones, W. M., Bejsovec, A. and Saint, R. (2008). Cell division requires a direct link between microtubule-bound RacGAP and Anillin in the contractile ring. Curr. Biol. 18, 25-29
16. Hu, C. K., Coughlin, M., Field, C. M. and Mitchison, T. J. (2008). Cell polarization during monopolar cytokinesis. J. Cell Biol. 181, 195-202
17. Kiyomitsu, T. and Cheeseman, I. M. (2012). Chromosome- and spindle-polederived signals generate an intrinsic code for spindle position and orientation Nat. Cell Biol. 14, 311-317
18. Kiyomitsu, T. and Cheeseman, I. M. (2013). Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase. Cell 154, 391-402
19. Krendel, M., Zenke, F. T. and Bokoch, G. M. (2002). Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton Nat. Cell Biol. 4, 294-301
20. Lekomtsev, S., Su, K. C., Pye, V. E., Blight, K., Sundaramoorthy, S., Takaki, T., Collinson, L. M., Cherepanov, P., Divecha, N. and Petronczki, M. (2012) Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis. Nature 492, 276-279
21. Lewellyn, L., Dumont, J., Desai, A. and Oegema, K. (2010). Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Mol. Biol. Cell 21, 50-62
22. Mishima, M., Kaitna, S. and Glotzer, M. (2002). Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. Dev. Cell 2, 41-54
23. Murthy, K. and Wadsworth, P. (2008). Dual role for microtubules in regulating cortical contractility during cytokinesis. J. Cell Sci. 121, 2350-2359
24. Oegema, K., Savoian, M. S., Mitchison, T. J. and Field, C. M. (2000). Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. J. Cell Biol. 150, 539-552
25. Petronczki, M., Glotzer, M., Kraut, N. and Peters, J. M. (2007). Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev. Cell 12, 713-725
26. Piekny, A. J. and Glotzer, M. (2008). Anillin is a scaffold protein that links RhoA, actin, and myosin during cytokinesis. Curr. Biol. 18, 30-36
27. Piekny, A. J. and Maddox, A. S. (2010). The myriad roles of Anillin during cytokinesis. Semin. Cell Dev. Biol. 21, 881-891
28. Piekny, A., Werner, M. and Glotzer, M. (2005). Cytokinesis: welcome to the Rho zone. Trends Cell Biol. 15, 651-658
29. Rankin, K. E. and Wordeman, L. (2010). Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow. J. Cell Biol. 190, 35-43
30. Saito, S., Tatsumoto, T., Lorenzi, M. V., Chedid, M., Kapoor, V., Sakata, H., Rubin, J. and Miki, T. (2003). Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N-terminal cell cycle regulatorrelated domains. J. Cell. Biochem. 90, 819-836
31. Sedzinski, J., Biro, M., Oswald, A., Tinevez, J. Y., Salbreux, G. and Paluch, E (2011). Polar actomyosin contractility destabilizes the position of the cytokinetic furrow. Nature 476, 462-466
32. Shannon, K. B., Canman, J. C., Ben Moree, C., Tirnauer, J. S. and Salmon, E. D. (2005). Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells. Mol. Biol. Cell 16, 4423-4436
33. Solinet, S., Mahmud, K., Stewman, S. F., Ben El Kadhi, K., Decelle, B., Talje, L., Ma, A., Kwok, B. H. and Carreno, S. (2013). The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex. J. Cell Biol. 202, 251-260
34. Somers, W. G. and Saint, R. (2003). A RhoGEF and Rho family GTPaseactivating protein complex links the contractile ring to cortical microtubules at the onset of cytokinesis. Dev. Cell 4, 29-39
35. Su, K. C., Takaki, T. and Petronczki, M. (2011). Targeting of the RhoGEF Ect2 to the equatorial membrane controls cleavage furrow formation during cytokinesis Dev. Cell 21, 1104-1115
36. Tse, Y. C., Piekny, A. and Glotzer, M. (2011). Anillin promotes astral microtubuledirected cortical myosin polarization. Mol. Biol. Cell 22, 3165-3175
37. Verbrugghe, K. J. and White, J. G. (2004). SPD-1 is required for the formation of the spindle midzone but is not essential for the completion of cytokinesis in C elegans embryos. Curr. Biol. 14, 1755-1760
38. von Dassow, G., Verbrugghe, K. J., Miller, A. L., Sider, J. R. and Bement, W. M (2009). Action at a distance during cytokinesis. J. Cell Biol. 187, 831-845
39. Werner, M., Munro, E. and Glotzer, M. (2007). Astral signals spatially bias cortical myosin recruitment to break symmetry and promote cytokinesis. Curr. Biol. 17, 1286-1297
40. Wolfe, B. A., Takaki, T., Petronczki, M. and Glotzer, M. (2009). Polo-like kinase 1 directs assembly of the HsCyk-4RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. PLoS Biol. 7, e1000110
41. Yüce, O., Piekny, A. and Glotzer, M. (2005). An ECT2-centralspindlin complex regulates the localization and function of RhoA. J. Cell Biol. 170, 571-582
42. Zanin, E., Desai, A., Poser, I., Toyoda, Y., Andree, C., Moebius, C., Bickle, M., Conradt, B., Piekny, A. and Oegema, K. (2013). A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis. Dev. Cell 26, 496-510
43. Zhao, W. M. and Fang, G. (2005a). Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis. J. Biol. Chem. 280, 33516-33524
44. Zhao, W. M. and Fang, G. (2005b). MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis. Proc. Natl. Acad. Sci. USA 102, 13158-13163