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Volumn 74, Issue 13, 2014, Pages 1457-1465

Rosacea: New and emerging treatments

Author keywords

[No Author keywords available]

Indexed keywords

BRIMONIDINE; DERMATOLOGICAL AGENT; IVERMECTIN; OXYMETAZOLINE; QUINOXALINE DERIVATIVE;

EID: 84906839647     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.1007/s40265-014-0281-x     Document Type: Review
Times cited : (25)

References (47)
  • 1
    • 84887884169 scopus 로고    scopus 로고
    • Rosacea: Current state of epidemiology
    • Tan J, Berg M. Rosacea: current state of epidemiology. J Am Acad Dermatol. 2013;69(6 Suppl 1):S27-35.
    • (2013) J Am Acad Dermatol , vol.69 , Issue.6 SUPPL. 1
    • Tan, J.1    Berg, M.2
  • 2
    • 84906834663 scopus 로고    scopus 로고
    • National Rosacea Society Accessed 28 Apr 2014
    • National Rosacea Society. If you have rosacea, you're not alone. 2014. http://www.rosacea.org/patients/index.php. Accessed 28 Apr 2014.
    • (2014) If You Have Rosacea, You're Not Alone
  • 3
    • 0036553649 scopus 로고    scopus 로고
    • Standard classification of rosacea: Report of the National Rosacea Society Expert Committee on the classification and staging of rosacea
    • Wilkin J, Dahl M, Detmar M, Drake L, Feinstein A, Odom R, et al. Standard classification of rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosacea. J Am Acad Dermatol. 2002;46(4):584-7.
    • (2002) J Am Acad Dermatol , vol.46 , Issue.4 , pp. 584-587
    • Wilkin, J.1    Dahl, M.2    Detmar, M.3    Drake, L.4    Feinstein, A.5    Odom, R.6
  • 5
    • 78650986541 scopus 로고    scopus 로고
    • Rosacea - global diversity and optimized outcome: Proposed international consensus from the Rosacea International Expert Group
    • Elewski BE, Draelos Z, Dreno B, Jansen T, Layton A, Picardo M. Rosacea - global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group. J Eur Acad Dermatol Venereol. 2011;25(2):188-200.
    • (2011) J Eur Acad Dermatol Venereol , vol.25 , Issue.2 , pp. 188-200
    • Elewski, B.E.1    Draelos, Z.2    Dreno, B.3    Jansen, T.4    Layton, A.5    Picardo, M.6
  • 6
    • 84887972065 scopus 로고    scopus 로고
    • New insights into rosacea pathophysiology: A review of recent findings
    • Steinhoff M, Schauber J, Leyden JJ. New insights into rosacea pathophysiology: a review of recent findings. J Am Acad Dermatol. 2013;69(6 Suppl 1):S15-26.
    • (2013) J Am Acad Dermatol , vol.69 , Issue.6 SUPPL. 1
    • Steinhoff, M.1    Schauber, J.2    Leyden, J.J.3
  • 9
    • 79951516747 scopus 로고    scopus 로고
    • TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes
    • Yamasaki K, Kanada K, Macleod DT, Borkowski AW, Morizane S, Nakatsuji T, et al. TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol. 2011;131(3):688-97.
    • (2011) J Invest Dermatol , vol.131 , Issue.3 , pp. 688-697
    • Yamasaki, K.1    Kanada, K.2    Macleod, D.T.3    Borkowski, A.W.4    Morizane, S.5    Nakatsuji, T.6
  • 11
    • 0026506431 scopus 로고
    • Rosacea: A study of clinical patterns, blood flow, and the role of Demodex folliculorum
    • Sibenge S, Gawkrodger DJ. Rosacea: a study of clinical patterns, blood flow, and the role of Demodex folliculorum. J Am Acad Dermatol. 1992;26(4):590-3.
    • (1992) J Am Acad Dermatol , vol.26 , Issue.4 , pp. 590-593
    • Sibenge, S.1    Gawkrodger, D.J.2
  • 13
    • 67649774232 scopus 로고    scopus 로고
    • The molecular pathology of rosacea
    • Yamasaki K, Gallo RL. The molecular pathology of rosacea. J Dermatol Sci. 2009;55(2):77-81.
    • (2009) J Dermatol Sci , vol.55 , Issue.2 , pp. 77-81
    • Yamasaki, K.1    Gallo, R.L.2
  • 14
    • 79955377117 scopus 로고    scopus 로고
    • Rosacea (erythematotelangiectatic type) effectively improved by topical xylometazoline
    • Kim JH, Oh YS, Ji JH, Bak H, Ahn SK. Rosacea (erythematotelangiectatic type) effectively improved by topical xylometazoline. J Dermatol. 2011;38(5):510-3.
    • (2011) J Dermatol , vol.38 , Issue.5 , pp. 510-513
    • Kim, J.H.1    Oh, Y.S.2    Ji, J.H.3    Bak, H.4    Ahn, S.K.5
  • 15
    • 84860352890 scopus 로고    scopus 로고
    • Advances in understanding and managing rosacea: Part 2: The central role, evaluation, and medical management of diffuse and persistent facial erythema of rosacea
    • Del Rosso JQ. Advances in understanding and managing rosacea: part 2: the central role, evaluation, and medical management of diffuse and persistent facial erythema of rosacea. J Clin Aesthet Dermatol. 2012;5(3):26-36.
    • (2012) J Clin Aesthet Dermatol , vol.5 , Issue.3 , pp. 26-36
    • Del Rosso, J.Q.1
  • 16
    • 84887858055 scopus 로고    scopus 로고
    • Management of facial erythema of rosacea: What is the role of topical alpha-adrenergic receptor agonist therapy?
    • Del Rosso JQ. Management of facial erythema of rosacea: what is the role of topical alpha-adrenergic receptor agonist therapy? J Am Acad Dermatol. 2013;69(6 Suppl 1):S44-56.
    • (2013) J Am Acad Dermatol , vol.69 , Issue.6 SUPPL. 1
    • Del Rosso, J.Q.1
  • 18
    • 36348992571 scopus 로고    scopus 로고
    • 1-adrenergic receptor agonist, oxymetazoline
    • DOI 10.1001/archderm.143.11.1369
    • Shanler SD, Ondo AL. Successful treatment of the erythema and flushing of rosacea using a topically applied selective alpha1-adrenergic receptor agonist, oxymetazoline. Arch Dermatol. 2007;143(11):1369-71. (Pubitemid 350146279)
    • (2007) Archives of Dermatology , vol.143 , Issue.11 , pp. 1369-1371
    • Shanler, S.D.1    Ondo, A.L.2
  • 19
    • 0027216053 scopus 로고
    • Density of Demodex folliculorum in rosacea: A case-control study using standardized skin-surface biopsy
    • Forton F, Seys B. Density of Demodex folliculorum in rosacea: a case-control study using standardized skin-surface biopsy. Br J Dermatol. 1993;128(6):650-9. (Pubitemid 23172024)
    • (1993) British Journal of Dermatology , vol.128 , Issue.6 , pp. 650-659
    • Forton, F.1    Seys, B.2
  • 20
    • 0032696259 scopus 로고    scopus 로고
    • Treatment of rosacea-like demodicidosis with oral ivermectin and topical permethrin cream
    • Forstinger C, Kittler H, Binder M. Treatment of rosacea-like demodicidosis with oral ivermectin and topical permethrin cream. J Am Acad Dermatol. 1999;41(5 Pt 1):775-7. (Pubitemid 29514037)
    • (1999) Journal of the American Academy of Dermatology , vol.41 , Issue.5 I , pp. 775-777
    • Forstinger, C.1    Kittler, H.2    Binder, M.3
  • 21
    • 84892772405 scopus 로고    scopus 로고
    • Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin
    • Brown M, Hernandez-Martin A, Clement A, Colmenero I, Torrelo A. Severe demodexfolliculorum-associated oculocutaneous rosacea in a girl successfully treated with ivermectin. JAMA Dermatol. 2014;150(1):61-3.
    • (2014) JAMA Dermatol , vol.150 , Issue.1 , pp. 61-63
    • Brown, M.1    Hernandez-Martin, A.2    Clement, A.3    Colmenero, I.4    Torrelo, A.5
  • 23
    • 34547875747 scopus 로고    scopus 로고
    • Mite-related bacterial antigens stimulate inflammatory cells in rosacea
    • DOI 10.1111/j.1365-2133.2007.08028.x
    • Lacey N, Delaney S, Kavanagh K, Powell FC. Mite-related bacterial antigens stimulate inflammatory cells in rosacea. Br J Dermatol. 2007;157(3):474-81. (Pubitemid 47256121)
    • (2007) British Journal of Dermatology , vol.157 , Issue.3 , pp. 474-481
    • Lacey, N.1    Delaney, S.2    Kavanagh, K.3    Powell, F.C.4
  • 24
    • 84888421942 scopus 로고    scopus 로고
    • Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 1: A status report on the disease state, general measures, and adjunctive skin care
    • Del Rosso JQ, Thiboutot D, Gallo R, Webster G, Tanghetti E, Eichenfield L, et al. Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 1: a status report on the disease state, general measures, and adjunctive skin care. Cutis. 2013;92(5):234-40.
    • (2013) Cutis , vol.92 , Issue.5 , pp. 234-240
    • Del Rosso, J.Q.1    Thiboutot, D.2    Gallo, R.3    Webster, G.4    Tanghetti, E.5    Eichenfield, L.6
  • 25
    • 80053508629 scopus 로고    scopus 로고
    • Effective and evidence-based management strategies for rosacea: Summary of a Cochrane systematic review
    • van Zuuren EJ, Kramer SF, Carter BR, Graber MA, Fedorowicz Z. Effective and evidence-based management strategies for rosacea: summary of a Cochrane systematic review. Br J Dermatol. 2011;165(4):760-81.
    • (2011) Br J Dermatol , vol.165 , Issue.4 , pp. 760-781
    • Van Zuuren, E.J.1    Kramer, S.F.2    Carter, B.R.3    Graber, M.A.4    Fedorowicz, Z.5
  • 26
    • 84894084730 scopus 로고    scopus 로고
    • Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 4: A status report on physical modalities and devices
    • Tanghetti E, Del Rosso JQ, Thiboutot D, Gallo R, Webster G, Eichenfield LF, et al. Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 4: a status report on physical modalities and devices. Cutis. 2014;93(2):71-6.
    • (2014) Cutis , vol.93 , Issue.2 , pp. 71-76
    • Tanghetti, E.1    Del Rosso, J.Q.2    Thiboutot, D.3    Gallo, R.4    Webster, G.5    Eichenfield, L.F.6
  • 27
    • 31344476048 scopus 로고    scopus 로고
    • Tetracyclines: Nonantibiotic properties and their clinical implications
    • DOI 10.1016/j.jaad.2005.10.004, PII S0190962205032317
    • Sapadin AN, Fleischmajer R. Tetracyclines: nonantibiotic properties and their clinical implications. J Am Acad Dermatol. 2006;54(2):258-65. (Pubitemid 43144395)
    • (2006) Journal of the American Academy of Dermatology , vol.54 , Issue.2 , pp. 258-265
    • Sapadin, A.N.1    Fleischmajer, R.2
  • 28
    • 79251607712 scopus 로고    scopus 로고
    • Clinical applications of non-antimicrobial tetracyclines in dermatology
    • Monk E, Shalita A, Siegel DM. Clinical applications of non-antimicrobial tetracyclines in dermatology. Pharmacol Res. 2011;63(2):130-45.
    • (2011) Pharmacol Res , vol.63 , Issue.2 , pp. 130-145
    • Monk, E.1    Shalita, A.2    Siegel, D.M.3
  • 29
    • 47249144220 scopus 로고    scopus 로고
    • Comparison of anti-inflammatory dose doxycycline versus doxycycline 100 mg in the treatment of rosacea
    • Del Rosso JQ, Schlessinger J, Werschler P. Comparison of anti-inflammatory dose doxycycline versus doxycycline 100 mg in the treatment of rosacea. J Drugs Dermatol. 2008;7(6):573-6.
    • (2008) J Drugs Dermatol , vol.7 , Issue.6 , pp. 573-576
    • Del Rosso, J.Q.1    Schlessinger, J.2    Werschler, P.3
  • 30
    • 34147119086 scopus 로고    scopus 로고
    • Two randomized phase III clinical trials evaluating anti-inflammatory dose doxycycline (40-mg doxycycline, USP capsules) administered once daily for treatment of rosacea
    • DOI 10.1016/j.jaad.2006.11.021, PII S0190962206040436
    • Del Rosso JQ, Webster GF, Jackson M, Rendon M, Rich P, Torok H, et al. Two randomized phase III clinical trials evaluating anti-inflammatory dose doxycycline (40-mg doxycycline, USP capsules) administered once daily for treatment of rosacea. J Am Acad Dermatol. 2007;56(5):791-802. (Pubitemid 46561002)
    • (2007) Journal of the American Academy of Dermatology , vol.56 , Issue.5 , pp. 791-802
    • Del, R.J.Q.1    Webster, G.F.2    Jackson, M.3    Rendon, M.4    Rich, P.5    Torok, H.6    Bradshaw, M.7
  • 31
    • 80755174557 scopus 로고    scopus 로고
    • Use of oral isotretinoin in the management of rosacea
    • Park H, Del Rosso JQ. Use of oral isotretinoin in the management of rosacea. J Clin Aesthet Dermatol. 2011;4(9):54-61.
    • (2011) J Clin Aesthet Dermatol , vol.4 , Issue.9 , pp. 54-61
    • Park, H.1    Del Rosso, J.Q.2
  • 32
    • 84901672379 scopus 로고    scopus 로고
    • Vasoconstriction and anti-inflammatory properties of the selective alpha-adrenergic receptor agonist brimonidine
    • Piwnica D, Rosignoli C, de Menonville ST, Alvarez T, Schuppli NM, Roye O, et al. Vasoconstriction and anti-inflammatory properties of the selective alpha-adrenergic receptor agonist brimonidine. J Dermatol Sci. 2014;75(1):49-54.
    • (2014) J Dermatol Sci , vol.75 , Issue.1 , pp. 49-54
    • Piwnica, D.1    Rosignoli, C.2    De Menonville, S.T.3    Alvarez, T.4    Schuppli, N.M.5    Roye, O.6
  • 33
    • 84863178633 scopus 로고    scopus 로고
    • Once-daily topical brimonidine tartrate gel 0.5% is a novel treatment for moderate to severe facial erythema of rosacea: Results of two multicentre, randomized and vehicle-controlled studies
    • Fowler J, Jarratt M, Moore A, Meadows K, Pollack A, Steinhoff M, et al. Once-daily topical brimonidine tartrate gel 0.5% is a novel treatment for moderate to severe facial erythema of rosacea: results of two multicentre, randomized and vehicle-controlled studies. Br J Dermatol. 2012;166(3):633-41.
    • (2012) Br J Dermatol , vol.166 , Issue.3 , pp. 633-641
    • Fowler, J.1    Jarratt, M.2    Moore, A.3    Meadows, K.4    Pollack, A.5    Steinhoff, M.6
  • 34
    • 84878653940 scopus 로고    scopus 로고
    • Efficacy and safety of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: Results of two randomized, double-blind, and vehicle-controlled pivotal studies
    • Fowler J Jr, Jackson M, Moore A, Jarratt M, Jones T, Meadows K, et al. Efficacy and safety of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: results of two randomized, double-blind, and vehicle-controlled pivotal studies. J Drugs Dermatol. 2013;12(6):650-6.
    • (2013) J Drugs Dermatol , vol.12 , Issue.6 , pp. 650-656
    • Fowler Jr., J.1    Jackson, M.2    Moore, A.3    Jarratt, M.4    Jones, T.5    Meadows, K.6
  • 35
    • 84892636148 scopus 로고    scopus 로고
    • Rebound erythema and burning sensation from a new topical brimonidine tartrate gel 0.33%
    • Routt ET, Levitt JO. Rebound erythema and burning sensation from a new topical brimonidine tartrate gel 0.33%. J Am Acad Dermatol. 2014;70(2):e37-8.
    • (2014) J Am Acad Dermatol , vol.70 , Issue.2
    • Routt, E.T.1    Levitt, J.O.2
  • 36
    • 84892888173 scopus 로고    scopus 로고
    • Long-term safety and efficacy of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: Results of a 1-year open-label study
    • Moore A, Kempers S, Murakawa G, Weiss J, Tauscher A, Swinyer L, et al. Long-term safety and efficacy of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: results of a 1-year open-label study. J Drugs Dermatol. 2014;13(1):56-61.
    • (2014) J Drugs Dermatol , vol.13 , Issue.1 , pp. 56-61
    • Moore, A.1    Kempers, S.2    Murakawa, G.3    Weiss, J.4    Tauscher, A.5    Swinyer, L.6
  • 37
    • 84906821992 scopus 로고    scopus 로고
    • Accessed 28 Apr 2014
    • National Institutes of Health. Oxymetazoline drug information. 2014. http://dailymed.nlm.nih.gov/dailymed/search.cfm?startswith=oxymetazoline&x= 0&y=0. Accessed 28 Apr 2014.
    • (2014) Oxymetazoline Drug Information
  • 38
    • 0027267938 scopus 로고
    • Inhibition of human neutrophil actin polymerization, phagocytosis and oxidative burst by components of decongestive nosedrops
    • Bjerknes R, Steinsvag SK. Inhibition of human neutrophil actin polymerization, phagocytosis and oxidative burst by components of decongestive nosedrops. Pharmacol Toxicol. 1993;73(1):41-5. (Pubitemid 23228841)
    • (1993) Pharmacology and Toxicology , vol.73 , Issue.1 , pp. 41-45
    • Bjerknes, R.1    Steinsvag, S.K.2
  • 40
    • 68749085165 scopus 로고    scopus 로고
    • Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway
    • Ci X, Li H, Yu Q, Zhang X, Yu L, Chen N, et al. Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway. Fundam Clin Pharmacol. 2009;23(4):449-55.
    • (2009) Fundam Clin Pharmacol , vol.23 , Issue.4 , pp. 449-455
    • Ci, X.1    Li, H.2    Yu, Q.3    Zhang, X.4    Yu, L.5    Chen, N.6
  • 41
    • 34548265825 scopus 로고    scopus 로고
    • Recalcitrant papulopustular rosacea in an immunocompetent patient responding to combination therapy with oral ivermectin and topical permethrin
    • Allen KJ, Davis CL, Billings SD, Mousdicas N. Recalcitrant papulopustular rosacea in an immunocompetent patient responding to combination therapy with oral ivermectin and topical permethrin. Cutis. 2007;80(2):149-51.
    • (2007) Cutis , vol.80 , Issue.2 , pp. 149-151
    • Allen, K.J.1    Davis, C.L.2    Billings, S.D.3    Mousdicas, N.4
  • 42
    • 33748257070 scopus 로고    scopus 로고
    • Ivermectin treatment of three cases of demodecidosis during human immunodeficiency virus infection
    • DOI 10.1111/j.1365-4632.2006.02924.x
    • Clyti E, Nacher M, Sainte-Marie D, Pradinaud R, Couppie P. Ivermectin treatment of three cases of demodecidosis during human immunodeficiency virus infection. Int J Dermatol. 2006;45(9):1066-8. (Pubitemid 44317121)
    • (2006) International Journal of Dermatology , vol.45 , Issue.9 , pp. 1066-1068
    • Clyti, E.1    Nacher, M.2    Sainte-Marie, D.3    Pradinaud, R.4    Couppie, P.5
  • 43
    • 84896377143 scopus 로고    scopus 로고
    • Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: Results of two randomized, double-blind, vehicle-controlled pivotal studies
    • Stein L, Kircik L, Fowler J, Tan J, Draelos Z, Fleischer A, et al. Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies. J Drugs Dermatol. 2014;13(3):316-23.
    • (2014) J Drugs Dermatol , vol.13 , Issue.3 , pp. 316-323
    • Stein, L.1    Kircik, L.2    Fowler, J.3    Tan, J.4    Draelos, Z.5    Fleischer, A.6
  • 45
    • 77953450297 scopus 로고    scopus 로고
    • Demodex dermatitis: A retrospective analysis of clinical diagnosis and successful treatment with topical crotamiton
    • Bikowski JB, Del Rosso JQ. Demodex dermatitis: a retrospective analysis of clinical diagnosis and successful treatment with topical crotamiton. J Clin Aesthet Dermatol. 2009;2(1):20-5.
    • (2009) J Clin Aesthet Dermatol , vol.2 , Issue.1 , pp. 20-25
    • Bikowski, J.B.1    Del Rosso, J.Q.2
  • 46
    • 84891644234 scopus 로고    scopus 로고
    • Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 2: A status report on topical agents
    • Del Rosso JQ, Thiboutot D, Gallo R, Webster G, Tanghetti E, Eichenfield L, et al. Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 2: a status report on topical agents. Cutis. 2013;92(6):277-84.
    • (2013) Cutis , vol.92 , Issue.6 , pp. 277-284
    • Del Rosso, J.Q.1    Thiboutot, D.2    Gallo, R.3    Webster, G.4    Tanghetti, E.5    Eichenfield, L.6
  • 47
    • 84893175012 scopus 로고    scopus 로고
    • Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 3: A status report on systemic therapies
    • Del Rosso JQ, Thiboutot D, Gallo R, Webster G, Tanghetti E, Eichenfield LF, et al. Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, part 3: a status report on systemic therapies. Cutis. 2014;93(1):18-28.
    • (2014) Cutis , vol.93 , Issue.1 , pp. 18-28
    • Del Rosso, J.Q.1    Thiboutot, D.2    Gallo, R.3    Webster, G.4    Tanghetti, E.5    Eichenfield, L.F.6


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