Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway

Fundamental and Clinical Pharmacology

Volumn 23, Issue 4, 2009, Pages 449-455

  Ci, Xinxin ^a   Li, Hongyu ^a   Yu, Qinlei ^a   Zhang, Xuemei ^a   Yu, Lu ^a   Chen, Na ^a   Song, Yu ^a   Deng, Xuming ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Avermectin; Cytokines; Lipopolysaccharide; Mitogen activated protein kinase; Nuclear transcription factor kappa B

Indexed keywords

AVERMECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE TRANSLOCATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EXCITATORY AMINO ACID AGONISTS; INFLAMMATION; IVERMECTIN; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; SIGNAL TRANSDUCTION;

EID: 68749085165     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2009.00684.x     Document Type: Article

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