Deleting multiple lytic genes enhances biomass yield and production of recombinant proteins by Bacillus subtilis

Microbial Cell Factories

Volumn 13, Issue 1, 2014, Pages

  Wang, Yi ^a   Chen, Zhenmin ^b,c   Zhao, Ruili ^a   Jin, Tingting ^a   Zhang, Xiaoming ^a   Chen, Xiangdong ^a,c  

^a WUHAN UNIVERSITY   (China)

^b HUAZHONG AGRICULTURAL UNIVERSITY   (China)

^c Hubei Provincial Cooperative Innovation Center of Industrial Fermentation   (China)

Author keywords

Bacillus subtilis; Biomass; Cell lysis; Multiple gene silencing; Nattokinase; Recombinant protein

Indexed keywords

BETA GALACTOSIDASE; HYDROLASE; RECOMBINANT PROTEIN; NATTOKINASE; SODIUM AZIDE; SUBTILISIN;

ANIMAL CELL; BACILLUS SUBTILIS; BACTERIAL GENE; BACTERIAL STRAIN; BIOMASS; BIOMASS PRODUCTION; CELL CULTURE; CONTROLLED STUDY; CYTOLYSIS; DELETION MUTANT; ENZYME RELEASE; ESCHERICHIA COLI; EXPRESSION VECTOR; GENE CLUSTER; GENE DELETION; GENE SILENCING; GENETIC CODE; MOLECULAR GENETICS; NONHUMAN; PROMOTER REGION; PROPHAGE; REVIEW; WILD TYPE; BACTERIOLYSIS; BIOSYNTHESIS; DRUG EFFECTS; GENETICS; INTRACELLULAR SPACE; METABOLISM;

BACILLUS SUBTILIS; BACTERIOLYSIS; BETA-GALACTOSIDASE; BIOMASS; GENE DELETION; GENES, BACTERIAL; INTRACELLULAR SPACE; RECOMBINANT PROTEINS; SODIUM AZIDE; SUBTILISINS;

EID: 84906836675     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-014-0129-9     Document Type: Review

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