Anti-inflammatory spirostanol and furostanol saponins from Solanum macaonense

Journal of Natural Products

Volumn 77, Issue 8, 2014, Pages 1770-1783

  Lee, Chia Lin ^a,b   Hwang, Tsong Long ^c   Yang, Juan Cheng ^a,b   Cheng, Hao Ting ^b   He, Wan Jung ^b   Yen, Chiao Ting ^d   Kuo, Chao Lin ^a   Chen, Chao Jung ^a,b   Chang, Wen Yi ^c,e   Wu, Yang Chang ^a,b,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

6ALPHA O BETA D XYLOPYRANOSYL (1-3) BETA QUINOVOPYRANOSYL 5 ALPHA SPIROSTAN 3BETA OL; ANTIINFLAMMATORY AGENT; CHLOROGENIN; CHLOROGENIN 6 O BETA D GLUCOPYRANOSIDE; CHLOROGENIN 6 O BETA D XYLOPYRANOSYL (1-3) BETA D GLUCOPYRANOSIDE; MACAOSIDE A; MACAOSIDE B; MACAOSIDE C; MACAOSIDE D; MACAOSIDE E; MACAOSIDE F; MACAOSIDE G; MACAOSIDE H; MACAOSIDE I; MACAOSIDE J; MACAOSIDE K; MACAOSIDE L; MACAOSIDE M; MACAOSIDE N; MACAOSIDE O; MACAOSIDE P; MACAOSIDE Q; MACAOSIDE R; PLANT EXTRACT; SAPONIN; SAPONIN SC 3; SAPONIN SC 4; SPIROSTANOL; UNCLASSIFIED DRUG; PANCREATIC ELASTASE; SPIROSTAN DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; HUMAN; HUMAN CELL; IC 50; NEUTROPHIL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLANUM; SOLANUM MACAONENSE; STRUCTURE ACTIVITY RELATION; CHEMICAL STRUCTURE; CHEMISTRY; IC50; ISOLATION AND PURIFICATION; METABOLISM; NUCLEAR MAGNETIC RESONANCE; TAIWAN;

ANTI-INFLAMMATORY AGENTS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PANCREATIC ELASTASE; SAPONINS; SOLANUM; SPIROSTANS; TAIWAN;

EID: 84906674914     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np500057b     Document Type: Article

References (19)

1. Boufford, D. E.; Hsieh, C.-F.; Huang, T.-C.; Lowry, P. P.; Ohashi, H.; Peng, C.-I.; Yang, S.-Y.; Hsiao, A.; Lin, H.-W.; Yu, C.-L. Flora of Taiwan; Editorial Committee of the Flora of Taiwan: Taipei, 1998; Vol. 4, pp 563, 569-570.
2. Zamilpa, A.; Tortoriello, J.; Navarro, V.; Delgado, G.; Alvarez, L. J. Nat. Prod. 2002, 65, 1815-1819
3. Mimaki, Y.; Sashida, Y.; Kawashima, K. Phytochemistry 1991, 30, 3721-3727
4. Mimaki, Y.; Sashida, Y.; Kawashima, K. Chem. Pharm. Bull. 1992, 40, 148-152
5. Agrawal, P. K. Magn. Reson. Chem. 2003, 41, 965-968
6. González, M.; Zamilpa, A.; Marquina, S.; Navarro, V.; Alvarez, L. J. Nat. Prod. 2004, 67, 938-941
7. Iida, Y.; Yanai, Y.; Ono, M.; Ikeda, T.; Nohara, T. Chem. Pharm. Bull. 2005, 53, 1122-1125
8. Lu, Y.; Luo, J.; Kong, L. Phytochemistry 2011, 72, 668-673
9. Song, G.; Yang, S.; Zhang, W.; Cao, Y.; Wang, P.; Ding, N.; Zhang, Z.; Guo, Y.; Li, Y. J. Med. Chem. 2009, 52, 7368-7371
10. Zhang, Y.; Li, Y.; Guo, T.; Guan, H.; Shi, J.; Yu, Q.; Yu, B. Carbohydr. Res. 2005, 340, 1453-1459
11. Agrawal, P. K. Steroids 2005, 70, 715-724
12. Agrawal, P. K.; Jain, D. C.; Gupta, R. K.; Thakur, R. S. Phytochemistry 1985, 24, 2479-2496
13. Lu, Y.; Luo, J.; Kong, L. Magn. Reson. Chem. 2009, 47, 808-812
14. Yahara, S.; Yamashita, T.; Nozawa, N.; Nohara, T. Phytochemistry 1996, 43, 1069-1074
15. Lee, C. L.; Hwang, T. L.; He, W. J.; Tsai, Y. H.; Yen, C. T.; Yen, H. F.; Chen, C. J.; Chang, W. Y.; Wu, Y. C. Phytochemistry 2013, 95, 315-321
16. Hwang, T. L.; Wang, C. C.; Kuo, Y. H.; Huang, H. C.; Wu, Y. C.; Kuo, L. M.; Wu, Y. H. Biochem. Pharmacol. 2010, 80, 1190-1200
17. Wu, Y. C.; Sureshbabu, M.; Fang, Y. C.; Wu, Y. H.; Lan, Y. H.; Chang, F. R.; Chang, Y. W.; Hwang, T. L. Toxicol. Appl. Pharmacol. 2013, 266, 399-407
18. Yang, J. C.; Lu, M. C.; Lee, C. L.; Chen, G. Y.; Lin, Y. Y.; Chang, F. R.; Wu, Y. C. Free Radical Biol. Med. 2011, 51, 641-657
19. Chen, B. H.; Hung, M. H.; Chen, J. Y. F.; Chang, H. W.; Yu, M. L.; Wan, L.; Tsai, F. J.; Wang, T. P.; Fu, T. F.; Chiu, C. C. Food Chem. 2012, 132, 968-974