Preparation and evaluation of a controlled drug release of repaglinide through matrix pellets: In vitro and in vivo studies

Journal of Microencapsulation

Volumn 31, Issue 6, 2014, Pages 529-534

  Tavakoli, Naser ^a   Minaiyan, Mohsen ^a   Tabbakhian, Majid ^a   Pendar, Yaqub ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Diabetes mellitus; Extrusion spheronisation; Microcrystalline cellulose

Indexed keywords

BUFFER; EUDRAGIT; GLUCOSE; GLYCEROL STEARATE; LACTOSE; MICROCRYSTALLINE CELLULOSE; PHOSPHATE; POLYMER; REPAGLINIDE; STREPTOZOCIN; XANTHAN; ANTIDIABETIC AGENT; CARBAMIC ACID DERIVATIVE; CELLULOSE; DRUG IMPLANT; GLUCOSE BLOOD LEVEL; PIPERIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG HALF LIFE; DRUG PELLET; DRUG SOLUBILITY; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; IN VIVO STUDY; MALE; MATRIX PELLET; NONHUMAN; PARTICLE SIZE; PELLET EXTRUSION; POWDER FLOW; PROCESS OPTIMIZATION; RAT; RAT MODEL; SPHERONIZATION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SUSTAINED DRUG RELEASE; TABLET FRIABILITY; ANIMAL; BLOOD; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DRUG IMPLANT; DRUG SCREENING; METABOLISM; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PHARMACOLOGY; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; CARBAMATES; CELLULOSE; DIABETES MELLITUS, EXPERIMENTAL; DRUG EVALUATION, PRECLINICAL; DRUG IMPLANTS; HYPOGLYCEMIC AGENTS; LACTOSE; MALE; PIPERIDINES; RATS; RATS, WISTAR;

EID: 84906540256     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2014.885604     Document Type: Article

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