A pH-sensitive theranostics system based on doxorubicin conjugated with the comb-shaped polymer coating of quantum dots

Journal of Materials Science

Volumn 49, Issue 21, 2014, Pages 7539-7546

  Wang, Yuzhen ^a   Zhang, Xiaonan ^b   Xu, Zheli ^a   Huang, Hailong ^a   Li, Yapeng ^a   Wang, Jingyuan ^a  

^a JILIN UNIVERSITY   (China)

^b THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC MONOMERS; GRAFTING (CHEMICAL); NANOPARTICLES; PLASTIC COATINGS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERS; SEMICONDUCTOR QUANTUM DOTS; THERMOGRAVIMETRIC ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY;

COMB POLYMERS; COMB-SHAPED POLYMERS; DRUG RELEASE SYSTEM; LIGAND EXCHANGES; POLY(GLYCIDYL METHACRYLATE); TRANSMISSION ELECTRON; TRANSMISSION SPECTRUMS; WELL-DISPERSED;

CONJUGATED POLYMERS;

EID: 84906323725     PISSN: 00222461     EISSN: 15734803     Source Type: Journal    
DOI: 10.1007/s10853-014-8461-3     Document Type: Article

References (27)

1. Gao XH, Cui YY, Levenson RM, Chung LWK, Nie SM (2004) In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 22:969-976
2. Ma ML, Zhang QY, Xin TJ, Zhang HP, Geng WC, Zhou J (2013) Preparation and characterization of structure-tailored magnetic fluorescent Fe3O4/P(GMA-EGDMA-NVCz) core-shell microspheres. J Mater Sci 48:5302-5308
3. Christoforou TK, Georgiou KT (2013) Polymeric theranostics: using polymer-based systems for simultaneous imaging and therapy. J Mater Chem B 1:3002-3025
4. Zhao Q, g Rong XL, Ma HB, Tao GH (2013) Aqueous synthesis of CdSe and CdSe/CdS quantum dots with controllable introduction of Se and S sources. J Mater Sci 48:2135-2141
5. Derfus AM, Chan WCW, Bhatia S (2004) Probing the cytotoxicity of semiconductor quantum dots. N Adv Mater 16:961-966
6. Gao XH, Yang LL, Petros JA, Marshall FF, Simons JW, Nie SM (2005) In vivo molecular and cellular imaging with quantum dots. Curr Opin Biotechnol 16:63-72
7. Ma YS, Zhang BB, Gu M, Huang SM, Liu XL, Liu B, Ni C (2013) Bulk synthesis of homogeneous and transparent bulk core/multishell quantum dots/PMMA nanocomposites with bright luminescence. J Appl Polym. doi: 10.1002/APP.39338
8. Macotela LGV, Torchynska TV, Douda J, Sierra RP, Shcherbyna (2011) Radiative interface state study in CdSe/ZnS quantum dots covered by polymer. L. Mater. Sci. Eng. B. 176:1349-1352
9. Zhang T, Yuan HP, Suo HL (2009) Water-soluble CdSe/ZnS quantum dots passivated by poly (glycino amino acid) phosphazenes. Trans Nonferrous Met Soc 19:645-650
10. Sun T, Li K, Li CJ, Zhao WO, Chen L, Chang YL (2012) Optimizing conditions for encapsulation of QDs by varying PEG chain density of amphiphilic centipede-like copolymer coating and exploration of QDs probes for tumor cell targeting and tracking. New J Chem 36:2383-2391
11. Zrazheyskiy P, Sena M, Gao XHChem (2010) Designing multifunctional quantum dots for bioimaging, detection, and drugdelivery. Soc Rev 39:4326-4354
12. Cui Y, Gong XQ, Zhu SJ, Li YH, Su WY, Yang QH, Chang J (2012) A facile method to prepare high-performance magnetic and fluorescent bifunctional nanocomposites and their preliminary application in biomolecule detection. J Mater Chem 22:462-469
13. Barat B, Sirk SJ, McCabe KE, Li J, Lepin EJ, Remenyi R, Koh AL, Olafsen T, Gambhir SS, Weiss S, Wu AM (2009) Cys-diabody quantum dot conjugates (immunoqdots) for cancer marker detection. Bioconjugate Chem 20:1474-1481
14. Medintz IL, Clapp AR, Brunel FM, Tiefenbrunn T, Uyeda HT, Chang EL, Deschamps JR, Dawson PE, Mattoussi H (2006) Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates. Nat Mater 5:581-589
15. Wang QQ, Kong M, An Y, Liu Y, Li JJ, Zhou X, Feng C, Li J, Jiang SY, Cheng XJ, Chen XG (2013) Hydroxybutyl chitosan thermo-sensitive hydrogel: a potential drug delivery system. J Mater Sci 48:5614-5623
16. Arap W, Pasqualini R, Ruoslahti E (1998) Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279:377-380
17. Gao QH, Han XL, Zhu J, Chen RJ, Sun BW (2012) A polymer-drug conjugate for doxorubicin: synthesis and biological evaluation of pluronic F127-doxorubicin amide conjugates. J Appl Ploym Sci 124:4960-5953
18. Kamimura M, Furukawa T, Akiyamac S, Nagasaki Y (2013) Enhanced intracellular drug delivery of pH-sensitive doxorubicin/poly(ethylene glycol)-block-poly(4-vinylbenzylphosphonate) nanoparticles in multi-drug resistant human epidermoid KB carcinoma cells. Biomater Sci 1:361-367
19. Bae Y, Fukushima S, Harada A, Kataoka K (2003) Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. Angew Chem 42:4640-4643
20. Zhao JH, Huang DT, Yin ZY, Chi XQ, Wang XM, Gao JH (2012) Magnetite nanoparticles as smart carriers to manipulate the cytotoxicity of anticancer drugs: magnetic control and pH-responsive release. J Mater Chem 22:15717-15725
21. Liu YS, Chen WB, Kim H (2012) pH-responsive release behavior of genipin-crosslinked chitosan/poly (ethylene glycol) hydrogels. J Appl Polym Sci 125:290-298
22. Wang YZ, Zhu M, Huang HL, Li YX, Li YP, Wang JY (2013) SYNTHESIS of comb polymer PGMA-g-EDA and studies of the modified quantum dots. Acta Polym Sin 8:1046-1309
23. Koktysh D, Bright V, Pham W (2011) Fluorescent magnetic hybrid nanoprobe for multimodal bioimaging. Nanotechnology 22:275606
24. Barrera C, Herrera AP, Rinaldi C (2009) Colloidal dispersions of monodisperse magnetite nanoparticles modified with poly (ethylene glycol). J Colloid Interf Sci 329:107-113
25. Zhao YL, Liu S, Li YP, Jiang W, Chang YL, Pan S, Fang XX, Wang YA, Wang JY (2010) Synthesis and grafting of folate-PEG-PAMAM conjugates onto quantum dots for selective targeting of folate-receptor-positive tumor cells. J Colloid Interf Sci 350:44-50
26. Tian Y, Glogowska A, Zhong W, Klonisch T, Xing M (2013) Polymeric mesoporous silica nanoparticles as a pH-responsive switch to controldoxorubicin intracellular delivery. J Mater Chem B 1:5264-5272
27. Palma RD, Peeters S, Bael MJV, Rul HVD, Bonroy K, Laureyn W, Mullens J, Borghs G, Maes G (2007) Silane ligand exchange to make hydrophobic superparamagnetic nanoparticles water-dispersible. Chem Mater 19:1821-1831