Prevalence of the TM6SF2 variant and non-alcoholic fatty liver disease in Chinese

Journal of Hepatology

Volumn 61, Issue 3, 2014, Pages 708-709

  Wong, Vincent Wai Sun ^a   Wong, Grace Lai Hung ^a   Tse, Chi Hang ^a   Chan, Henry Lik Yuen ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; MEMBRANE PROTEIN; TM6SF2 PROTEIN, HUMAN;

ASIAN; CHOLESTEROL BLOOD LEVEL; DISEASE SEVERITY; GENE; GENETIC VARIABILITY; GENOTYPE; HUMAN; LETTER; LIVER CIRRHOSIS; LIVER FIBROSIS; NONALCOHOLIC FATTY LIVER; PREVALENCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEATOSIS; TM6SF2 GENE; TRIACYLGLYCEROL BLOOD LEVEL; ADULT; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COHORT ANALYSIS; ELASTICITY; FEMALE; GENETICS; LIVER; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COHORT STUDIES; ELASTICITY; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; LIVER; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; PREVALENCE;

EID: 84906322683     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2014.04.047     Document Type: Letter

References (7)

1. J. Hyysalo, V.T. Männistö, Y. Zhou, J. Arola, V. Kärjä, and M. Leivonen et al. A population-based study on the prevalence of NASH using scores validated against liver histology J Hepatol 60 2014 839 846
2. K.C. Sung, S.H. Wild, and C.D. Byrne Development of new fatty liver, or resolution of existing fatty liver, over five years of follow-up, and risk of incident hypertension J Hepatol 60 2014 1040 1045
3. V.W. Wong, W.C. Chu, G.L. Wong, R.S. Chan, A.M. Chim, and A. Ong et al. Prevalence of non-alcoholic fatty liver disease and advanced fibrosis in Hong Kong Chinese: a population study using proton-magnetic resonance spectroscopy and transient elastography Gut 61 2012 409 415
4. J. Kozlitina, E. Smagris, S. Stender, B.G. Nordestgaard, H.H. Zhou, and A. Tybjærg-Hansen et al. Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease Nat Genet 46 2014 352 356
5. O.L. Holmen, H. Zhang, Y. Fan, D.H. Hovelson, E.M. Schmidt, and W. Zhou et al. Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk Nat Genet 46 2014 345 351
6. S. Petta, S. Grimaudo, C. Cammà, D. Cabibi, V. Di Marco, and G. Licata et al. IL28B and PNPLA3 polymorphisms affect histological liver damage in patients with non-alcoholic fatty liver disease J Hepatol 56 2012 1356 1362
7. V.W. Wong, J. Vergniol, G.L. Wong, J. Foucher, H.L. Chan, and B. Le Bail et al. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease Hepatology 51 2010 454 462