Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease

International Journal of Cardiology

Volumn 176, Issue 1, 2014, Pages 99-109

  Charytan, David M ^a   Padera, Robert ^a   Helfand, Alexander M ^a   Zeisberg, Michael ^b   Xu, Xingbo ^b   Liu, Xiaopeng ^b   Himmelfarb, Jonathan ^c   Cinelli, Angeles ^a   Kalluri, Raghu ^c   Zeisberg, Elisabeth M ^b,d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Angiogenesis inhibitor; Cardiovascular disease; CKD; Endothelial to mesenchymal transition; ESRD; Fibrosis

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOPOIETIN 2; ENDOSTATIN; N(G),N(G) DIMETHYLARGININE; RNA; THROMBOSPONDIN 2; BIOLOGICAL MARKER; NITRIC OXIDE;

ADULT; AGED; APOPTOSIS; ARTICLE; BLOOD SAMPLING; CAPILLARY DENSITY; CARDIOVASCULAR DISEASE; CELL PROLIFERATION; CELL TRANSFORMATION; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; END STAGE RENAL DISEASE; ENDOTHELIAL MESENCHYMAL TRANSITION; ENDOTHELIUM CELL; FEMALE; FIBROBLAST; GENE EXPRESSION; HEART; HEART MUSCLE FIBROSIS; HEART SURGERY; HUMAN; HUMAN CELL; HUMAN CORONARY ARTERY ENDOTHELIAL CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY FUNCTION; MALE; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; BLOOD; CELL CULTURE; COHORT ANALYSIS; EPITHELIAL MESENCHYMAL TRANSITION; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RENAL INSUFFICIENCY, CHRONIC; VASCULAR ENDOTHELIUM; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANGIOGENESIS INHIBITORS; BIOMARKERS; CELLS, CULTURED; COHORT STUDIES; ENDOTHELIUM, VASCULAR; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE; RENAL INSUFFICIENCY, CHRONIC;

EID: 84906322326     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.06.062     Document Type: Article

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