Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase

Nature Chemical Biology

Volumn 10, Issue 9, 2014, Pages 707-709

  Gidon, Alexandre ^a   Al Bataineh, Mohammad M ^a   Jean Alphonse, Frederic G ^a   Stevenson, Hilary P ^a   Watanabe, Tomoyuki ^b   Louet, Claire ^a   Khatri, Ashok ^b   Calero, Guillermo ^a   Pastor Soler, Núria M ^a   Gardella, Thomas J ^b   Vilardaga, Jean Pierre ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BAFILOMYCIN; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR;

ACIDIFICATION; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; NEGATIVE FEEDBACK; PH; PRIORITY JOURNAL; RADIOASSAY; THERMAL INJURY; THERMOSTABILITY;

ARRESTINS; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOSOMES; FEEDBACK, PHYSIOLOGICAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; PHOSPHORYLATION; PROTEIN BINDING; RECEPTOR, PARATHYROID HORMONE, TYPE 1; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84906305724     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1589     Document Type: Article

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