Homogeneous assay development for nuclear receptor using AlphaScreen™ technology

Handbook of Assay Development in Drug Discovery

Volumn , Issue , 2006, Pages 193-207

  Rouleau, Nathalie ^a   Bossé, Roger ^a  

^a INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84906301172     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (11)

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2. Wu X, Glickman JF, Bowen BR, Sills MA. Comparison of assay technologies for a nuclear receptor assay screen reveals differences in the sets of identified functional antagonists. J Biomol Screen 2003; 8:381-392.
3. Rouleau N, Turcotte S, Mondou M-H, Roby P, Bossé R. Development of a versatile platform for nuclear receptor screening using AlphaScreen™. J Biomol Screen 2003; 8:191-197.
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9. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung L. Nuclear receptor coactivators and corepressors. Mol Endocrinol 1996; 10:1167-1177.
10. Liu Z, Auboeuf D, Wong J, Chen JD, Tsai SY, Tsai MJ, O'Malley BW. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci USA 2002; 99:7940-7944.
11. Beaudet L, Bedard J, Breton B, Mercuri RJ, Budarf ML. Homogeneous assays for single-nucleotide polymorphism typing using AlphaScreen. Genome Res 2001; 11:600-608.