In vivo magnetic resonance imaging of tumor protease activity

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Haris, Mohammad ^a,b   Singh, Anup ^a,c   Mohammed, Imran ^a   Ittyerah, Ranjit ^d   Nath, Kavindra ^d   Nanga, Ravi Prakash Reddy ^a   Debrosse, Catherine ^a   Kogan, Feliks ^a   Cai, Kejia ^a,e   Poptani, Harish ^d   Reddy, Damodar ^a   Hariharan, Hari ^a   Reddy, Ravinder ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SIDRA MEDICAL AND RESEARCH CENTER   (Qatar)

^c INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN; CONTRAST MEDIUM; POLYGLUTAMIC ACID;

ANIMAL; BIOSYNTHESIS; CHEMISTRY; FEMALE; FISCHER 344 RAT; GLIOSARCOMA; IMAGING PHANTOM; NUCLEAR MAGNETIC RESONANCE IMAGING; PROCEDURES; RADIOGRAPHY; RAT; TUMOR CELL LINE;

ANIMALS; CATHEPSINS; CELL LINE, TUMOR; CONTRAST MEDIA; FEMALE; GLIOSARCOMA; MAGNETIC RESONANCE IMAGING; PHANTOMS, IMAGING; POLYGLUTAMIC ACID; RATS; RATS, INBRED F344;

EID: 84906258696     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep06081     Document Type: Article

References (25)

1. Koblinski, J. E., Ahram, M. &Sloane, B. F. Unraveling the role of proteases in cancer. Clin Chim Acta 291, 113-135 (2000). (Pubitemid 30089760)
2. Jedeszko, C. &Sloane, B. F. Cysteine cathepsins in human cancer. Biol Chem 385, 1017-1027 (2004). (Pubitemid 39600309)
3. Mohamed, M. M. &Sloane, B. F. Cysteine cathepsins: multifunctional enzymes in cancer. Nat Rev Cancer 6, 764-775 (2006). (Pubitemid 44450465)
4. Keppler, D.& Sloane, B. F. Cathepsin B: multiple enzyme forms from a single gene and their relation to cancer. Enzyme Protein 49, 94-105 (1996). (Pubitemid 26181740)
5. Foekens, J. A. et al. Prognostic significance of cathepsins B and L in primary human breast cancer. J Clin Oncol 16, 1013-1021 (1998). (Pubitemid 28108735)
6. Nouh, M. A. et al. Cathepsin B: a potential prognostic marker for inflammatory breast cancer. J Transl Med 9, 1 (2011).
7. Strojan, P. et al. Prognostic significance of cysteine proteinases cathepsins B and L and their endogenous inhibitors stefins A and B in patients with squamous cell carcinoma of the head and neck. Clin Cancer Res 6, 1052-1062 (2000). (Pubitemid 30159367)
8. Gong, F. et al. Cathepsin B as a potential prognostic and therapeutic marker for human lung squamous cell carcinoma. Mol Cancer 12, 125 (2013).
9. Blum, G. et al. Dynamic imaging of protease activity with fluorescently quenched activity-based probes. Nat Chem Biol 1, 203-209 (2005).
10. Blum, G., von Degenfeld, G., Merchant, M. J., Blau, H. M. &Bogyo, M. Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes. Nat Chem Biol 3, 668-677 (2007). (Pubitemid 47417706)
11. Bremer, C. et al. Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes. Invest Radiol 40, 321-327 (2005). (Pubitemid 40734559)
12. Weissleder, R., Tung, C. H., Mahmood, U. &Bogdanov, A. Jr. In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat Biotechnol 17, 375-378 (1999). (Pubitemid 29166041)
13. Melancon, M. P. et al. A novel method for imaging in vivo degradation of poly(Lglutamic acid), a biodegradable drug carrier. Pharm Res 24, 1217-1224 (2007). (Pubitemid 46798898)
14. Kenny, A. D. Evaluation of sodium poly-alpha, L-glutamate as a plasma expander. Proc Soc Exp Biol Med 100, 778-780 (1959).
15. Kishore, B. K. et al.Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids. J Pharmacol Exp Ther 255, 875-885 (1990).
16. Li, C. Poly(L-glutamic acid)-anticancer drug conjugates. Adv Drug Deliv Rev 54, 695-713 (2002). (Pubitemid 35247523)
17. Sumi, H., Kawabe, K. &Nakajima, N. Effect of various polyamino acids and Dand L-amino acids on the blood fibrinolytic system. Comp Biochem Physiol B 102, 159-162 (1992).
18. Cai, K. et al. Magnetic resonance imaging of glutamate. Nat Med 18, 302-306 (2012).
19. Duncan, R. Polymer conjugates as anticancer nanomedicines. Nat Rev Cancer 6, 688-701 (2006). (Pubitemid 44286001)
20. Li, C. et al. Antitumor activity of poly(L-glutamic acid)-paclitaxel on syngeneic and xenografted tumors. Clin Cancer Res 5, 891-897 (1999). (Pubitemid 29180842)
21. Li, C. et al. Complete regression of well-established tumors using a novel watersoluble poly(L-glutamic acid)-paclitaxel conjugate. Cancer Res 58, 2404-2409 (1998). (Pubitemid 28252701)
22. Yang, Y., Hong, H., Zhang, Y. &Cai, W. Molecular Imaging of Proteases in Cancer. Cancer Growth Metastasis 2, 13-27 (2009).
23. Kim, H. S. et al. Comparison of the efficacy and safety of paclitaxel-eluting coroflex please stents and paclitaxel-eluting stents in patients with coronary artery disease: a randomized PIPA trial. Catheter Cardiovasc Interv 80, 799-806 (2012).
24. Li, C. &Wallace, S. Polymer-drug conjugates: recent development in clinical oncology. Adv Drug Deliv Rev 60, 886-898 (2008).
25. Kim, S., Pickup, S., Hsu, O. &Poptani, H. Diffusion tensor MRI in rat models of invasive and well-demarcated brain tumors. NMR Biomed 21, 208-216 (2008). (Pubitemid 351513668)