Nitric oxide increases the invasion of pancreatic cancer cells via activation of the PI3K-AKT and RhoA pathways after carbon ion irradiation

FEBS Letters

Volumn 588, Issue 17, 2014, Pages 3240-3250

  Fujita, Mayumi ^a   Imadome, Kaori ^a   Endo, Satoshi ^a   Shoji, Yoshimi ^a   Yamada, Shigeru ^a   Imai, Takashi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

Invasion; Nitric oxide synthase; Phosphatidylinositol 3 kinase; Plasminogen activator; Rho; v akt murine thymoma viral oncogene homolog 2

Indexed keywords

ACTIN; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; BINDING AFFINITY; CANCER CELL; CELL COUNT; CELL DEATH; CELL INVASION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; ION THERAPY; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RADIATION DOSE; UPREGULATION;

MURINAE;

INVASION; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3-KINASE; PLASMINOGEN ACTIVATOR; RHO; V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 2;

CELL LINE, TUMOR; DNA DAMAGE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAVY ION RADIOTHERAPY; HUMANS; NEOPLASM INVASIVENESS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PANCREATIC NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84906248653     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.07.006     Document Type: Article

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