메뉴 건너뛰기




Volumn 18, Issue 9, 2014, Pages 973-977

Adenosine pathway and cancer: Where do we go from here?

Author keywords

Adenosine; Adenosine receptors; Cancer; CD73; Immune system; Inflammation; Novel therapies

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; ADENOSINE RECEPTOR; ANTINEOPLASTIC AGENT;

EID: 84906240747     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2014.925883     Document Type: Review
Times cited : (19)

References (24)
  • 1
    • 84904433795 scopus 로고    scopus 로고
    • Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer
    • Allard B, Turcotte M, Stagg J. Targeting CD73 and downstream adenosine receptor signaling in triple-negative breast cancer. Expert Opin Ther Targets 2014;18(8):863-81
    • (2014) Expert Opin Ther Targets , vol.18 , Issue.8 , pp. 863-881
    • Allard, B.1    Turcotte, M.2    Stagg, J.3
  • 2
    • 84888385324 scopus 로고    scopus 로고
    • Immunity, inflammation and cancer: A leading role for adenosine
    • Antonioli L, Blandizzi C, Pacher P, et al. Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer 2013;13(12):842-57
    • (2013) Nat Rev Cancer , vol.13 , Issue.12 , pp. 842-857
    • Antonioli, L.1    Blandizzi, C.2    Pacher, P.3
  • 3
    • 61349158530 scopus 로고    scopus 로고
    • T regulatory cells: Hypoxia-adenosinergic suppression and re-direction of the immune response
    • Sitkovsky MV. T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response. Trends Immunol 2009;30(3):102-8
    • (2009) Trends Immunol , vol.30 , Issue.3 , pp. 102-108
    • Sitkovsky, M.V.1
  • 4
    • 84878614399 scopus 로고    scopus 로고
    • CD39 and CD73 in immunity and inflammation
    • Antonioli L, Pacher P, Vizi ES, et al. CD39 and CD73 in immunity and inflammation. Trends Mol Med 2013;19(6):355-67
    • (2013) Trends Mol Med , vol.19 , Issue.6 , pp. 355-367
    • Antonioli, L.1    Pacher, P.2    Vizi, E.S.3
  • 5
    • 34547120458 scopus 로고    scopus 로고
    • Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues
    • Lukashev D, Ohta A, Sitkovsky M. Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues. Cancer Metastasis Rev 2007;26(2):273-9
    • (2007) Cancer Metastasis Rev , vol.26 , Issue.2 , pp. 273-279
    • Lukashev, D.1    Ohta, A.2    Sitkovsky, M.3
  • 6
    • 77950231071 scopus 로고    scopus 로고
    • CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumor-induced immune suppression
    • Jin D, Fan J, Wang L, et al. CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression. Cancer Res 2010;70(6):2245-55
    • (2010) Cancer Res , vol.70 , Issue.6 , pp. 2245-2255
    • Jin, D.1    Fan, J.2    Wang, L.3
  • 7
    • 84862317836 scopus 로고    scopus 로고
    • Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
    • Waickman AT, Alme A, Senaldi L, et al. Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor. Cancer Immunol Immunother 2012;61(6):917-26
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.6 , pp. 917-926
    • Waickman, A.T.1    Alme, A.2    Senaldi, L.3
  • 8
    • 84883422236 scopus 로고    scopus 로고
    • Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors
    • Beavis PA, Divisekera U, Paget C, et al. Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors. Proc Natl Acad Sci USA 2013;110(36):14711-16
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.36 , pp. 14711-14716
    • Beavis, P.A.1    Divisekera, U.2    Paget, C.3
  • 9
    • 85047685683 scopus 로고    scopus 로고
    • Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia
    • Synnestvedt K, Furuta GT, Comerford KM, et al. Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J Clin Invest 2002;110(7):993-1002
    • (2002) J Clin Invest , vol.110 , Issue.7 , pp. 993-1002
    • Synnestvedt, K.1    Furuta, G.T.2    Comerford, K.M.3
  • 10
    • 2442478198 scopus 로고    scopus 로고
    • Wnt and betacatenin signaling target the expression of ecto-5'-nucleotidase and increase extracellular adenosine generation
    • Spychala J, Kitajewski J. Wnt and betacatenin signaling target the expression of ecto-5'-nucleotidase and increase extracellular adenosine generation. Exp Cell Res 2004;296(2):99-108
    • (2004) Exp Cell Res , vol.296 , Issue.2 , pp. 99-108
    • Spychala, J.1    Kitajewski, J.2
  • 11
    • 84869039651 scopus 로고    scopus 로고
    • CD73-generated adenosine: Orchestrating the tumor-stroma interplay to promote cancer growth
    • Allard B, Turcotte M, Stagg J. CD73-generated adenosine: orchestrating the tumor-stroma interplay to promote cancer growth. J Biomed Biotechnol 2012;2012:485156
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 485156
    • Allard, B.1    Turcotte, M.2    Stagg, J.3
  • 12
    • 79954576658 scopus 로고    scopus 로고
    • CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis
    • Stagg J, Divisekera U, Duret H, et al. CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis. Cancer Res 2011;71(8):2892-900
    • (2011) Cancer Res , vol.71 , Issue.8 , pp. 2892-2900
    • Stagg, J.1    Divisekera, U.2    Duret, H.3
  • 13
    • 84891824680 scopus 로고    scopus 로고
    • Anti-CD73 therapy impairs tumor angiogenesis
    • Allard B, Turcotte M, Spring K, et al. Anti-CD73 therapy impairs tumor angiogenesis. Int J Cancer 2014;134(6):1466-73
    • (2014) Int J Cancer , vol.134 , Issue.6 , pp. 1466-1473
    • Allard, B.1    Turcotte, M.2    Spring, K.3
  • 14
    • 84869078806 scopus 로고    scopus 로고
    • Production of adenosine by ectonucleotidases: A key factor in tumor immunoescape
    • Ghiringhelli F, Bruchard M, Chalmin F, et al. Production of adenosine by ectonucleotidases: a key factor in tumor immunoescape. J Biomed Biotechnol 2012;2012:473712
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 473712
    • Ghiringhelli, F.1    Bruchard, M.2    Chalmin, F.3
  • 15
    • 75949112218 scopus 로고    scopus 로고
    • Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
    • Stagg J, Divisekera U, McLaughlin N, et al. Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proc Natl Acad Sci USA 2010;107(4):1547-52
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.4 , pp. 1547-1552
    • Stagg, J.1    Divisekera, U.2    McLaughlin, N.3
  • 16
    • 84874283227 scopus 로고    scopus 로고
    • Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type
    • Rust S, Guillard S, Sachsenmeier K, et al. Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type. Mol Cancer 2013;12:11
    • (2013) Mol Cancer , vol.12 , pp. 11
    • Rust, S.1    Guillard, S.2    Sachsenmeier, K.3
  • 17
    • 84879705407 scopus 로고    scopus 로고
    • CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
    • Loi S, Pommey S, Haibe-Kains B, et al. CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer. Proc Natl Acad Sci USA 2013;110(27):11091-6
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.27 , pp. 11091-11096
    • Loi, S.1    Pommey, S.2    Haibe-Kains, B.3
  • 18
    • 77955750932 scopus 로고    scopus 로고
    • CD73: A novel target for cancer immunotherapy
    • Zhang B. CD73: a novel target for cancer immunotherapy. Cancer Res 2010;70(16):6407-11
    • (2010) Cancer Res , vol.70 , Issue.16 , pp. 6407-6411
    • Zhang, B.1
  • 19
    • 0033820684 scopus 로고    scopus 로고
    • Adenosine inhibits IL-12 and TNF- [alpha] production via adenosine A2a receptor-dependent and independent mechanisms
    • Haskó G, Kuhel DG, Chen JF, et al. Adenosine inhibits IL-12 and TNF- [alpha] production via adenosine A2a receptor-dependent and independent mechanisms. FASEB J 2000;14(13):2065-74
    • (2000) FASEB J , vol.14 , Issue.13 , pp. 2065-2074
    • Haskó, G.1    Kuhel, D.G.2    Chen, J.F.3
  • 20
    • 0030588630 scopus 로고    scopus 로고
    • Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264. 7 macrophages and in endotoxemic mice
    • Haskó G, Szabó C, Németh ZH, et al. Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264. 7 macrophages and in endotoxemic mice. J Immunol 1996;157(10):4634-40
    • (1996) J Immunol , vol.157 , Issue.10 , pp. 4634-4640
    • Haskó, G.1    Szabó, C.2    Németh, Z.H.3
  • 21
    • 79956191026 scopus 로고    scopus 로고
    • Adenosine A2B receptor antagonist suppresses differentiation to regulatory T cells without suppressing activation of T cells
    • Nakatsukasa H, Tsukimoto M, Harada H, et al. Adenosine A2B receptor antagonist suppresses differentiation to regulatory T cells without suppressing activation of T cells. Biochem Biophys Res Commun 2011;409(1):114-19
    • (2011) Biochem Biophys Res Commun , vol.409 , Issue.1 , pp. 114-119
    • Nakatsukasa, H.1    Tsukimoto, M.2    Harada, H.3
  • 22
    • 84891612009 scopus 로고    scopus 로고
    • Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma
    • Iannone R, Miele L, Maiolino P, et al. Blockade of A2b adenosine receptor reduces tumor growth and immune suppression mediated by myeloid-derived suppressor cells in a mouse model of melanoma. Neoplasia 2013;15(12):1400-9
    • (2013) Neoplasia , vol.15 , Issue.12 , pp. 1400-1409
    • Iannone, R.1    Miele, L.2    Maiolino, P.3
  • 23
    • 84873044693 scopus 로고    scopus 로고
    • CF102 for the treatment of hepatocellular carcinoma: A phase I/II, open-label,dose-escalation study
    • Stemmer SM, Benjaminov O, Medalia G, et al. CF102 for the treatment of hepatocellular carcinoma: a phase I/II, open-label,dose-escalation study. Oncologist 2013;18(1):25-6
    • (2013) Oncologist , vol.18 , Issue.1 , pp. 25-26
    • Stemmer, S.M.1    Benjaminov, O.2    Medalia, G.3
  • 24
    • 33748357735 scopus 로고    scopus 로고
    • A2A adenosine receptor protects tumors from antitumor T cells
    • Ohta A, Gorelik E, Prasad SJ, et al. A2A adenosine receptor protects tumors from antitumor T cells. Proc Natl Acad Sci USA 2006;103(35):13132-7
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.35 , pp. 13132-13137
    • Ohta, A.1    Gorelik, E.2    Prasad, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.