Evaluation of the usefulness of novel biomarkers for drug-induced acute kidney injury in beagle dogs

Toxicology and Applied Pharmacology

Volumn 280, Issue 1, 2014, Pages 30-35

  Zhou, Xiaobing ^a,b   Ma, Ben ^a   Lin, Zhi ^a   Qu, Zhe ^a   Huo, Yan ^a   Wang, Jufeng ^a   Li, Bo ^a,b  

^a NATIONAL INSTITUTES FOR FOOD AND DRUG CONTROL   (China)

^b GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Beagle dogs; Biomarkers; Clusterin; Nephrotoxicity; Neutrophil gelatinase associated lipocalin; Preclinical study

Indexed keywords

BIOLOGICAL MARKER; CLUSTERIN; GENTAMICIN; N ACETYL BETA GLUCOSAMINIDASE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; PROTEIN; ACUTE PHASE PROTEIN; ANTIINFECTIVE AGENT; LIPOCALIN; NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN PROTEIN, DOG; ONCOPROTEIN; UNCLASSIFIED DRUG; URINARY TOTAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEAGLE; BLOOD CHEMISTRY; DRUG INDUCED ACUTE KIDNEY INJURY; GENE EXPRESSION; HISTOPATHOLOGY; KIDNEY PROXIMAL TUBULE; MALE; NEPHROTOXICITY; NONHUMAN; TOXICITY TESTING; URINALYSIS; ANIMAL; BLOOD; DOG; DRUG SCREENING; DRUG-INDUCED LIVER INJURY; PROCEDURES; RANDOMIZATION; URINE; ACUTE KIDNEY FAILURE; ANIMAL MODEL; CLINICAL CHEMISTRY; CONTROLLED STUDY; GENE EXPRESSION ASSAY; PROTEIN URINE LEVEL; RECEIVER OPERATING CHARACTERISTIC;

ACUTE-PHASE PROTEINS; ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL MARKERS; CLUSTERIN; DOGS; DRUG EVALUATION, PRECLINICAL; DRUG-INDUCED LIVER INJURY; GENTAMICINS; LIPOCALINS; MALE; PROTO-ONCOGENE PROTEINS; RANDOM ALLOCATION;

EID: 84906219054     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.07.002     Document Type: Article

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