In vitro induction of apoptosis by isosclerone from marine-derived fungus Aspergillus fumigatus

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 16, 2014, Pages 3923-3927

  Li, Yong Xin ^a   Kang, Kyong Hwa ^a   Kim, Hak Jun ^a   Kim, Se Kwon ^a  

^a Pukyong National University   (South Korea)

Author keywords

Apoptosis; Bcl 2 family; Caspase 3 8 and 9; Isosclerone; Small molecule docking

Indexed keywords

ANTINEOPLASTIC AGENT; ISOSCLERONE; NAPHTHALENE DERIVATIVE; CASPASE 3; CASPASE 8; CASPASE 9; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROCASPASE 3; PROTEIN BCL 2; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

APOPTOSIS; ASPERGILLUS FUMIGATUS; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HUMAN; ISOLATION AND PURIFICATION; MCF 7 CELL LINE; STRUCTURE ACTIVITY RELATION; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; CRYSTAL STRUCTURE; CYTOTOXICITY; DNA FRAGMENTATION; DOWN REGULATION; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ASPERGILLUS FUMIGATUS; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NAPHTHALENES; STRUCTURE-ACTIVITY RELATIONSHIP;

ASPERGILLUS FUMIGATUS; FUNGI;

EID: 84906101835     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.06.042     Document Type: Article

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