Sperm concentration, hyaluronic acid-binding capacity, aneuploidy and persistent histones in testicular cancer

Human Reproduction

Volumn 29, Issue 9, 2014, Pages 1866-1874

  Molnar, Z ^a   Mokanszki, A ^a   Bazsane, Z Kassai ^a   Bhattoa, H P ^a   Benyo, M ^a   Olah, E ^a   Jakab, A ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

aniline blue staining; human sperm fluorescence in situ hybridization; hyaluronic acid binding assay; infertility; testicular cancer

Indexed keywords

ANILINE; HISTONE; HYALURONIC ACID;

ADULT; ANEUPLOIDY; ARTICLE; BINDING ASSAY; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER THERAPY; CHROMOSOME 17; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; CRYOPRESERVATION; DIPLOIDY; DISOMY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; INFERTILE OLIGOZOOSPERMIC; MALE; MALE GENITAL TRACT PARAMETERS; MALE INFERTILITY; NORMOZOOSPERMIC; NUMERICAL CHROMOSOME ABERRATION; ORCHIECTOMY; PRACTICE GUIDELINE; SEMEN ANALYSIS; SEX CHROMOSOME; SPERMATOGENESIS; SPERMATOZOON; SPERMATOZOON DENSITY; STAINING; TESTIS CANCER; WORLD HEALTH ORGANIZATION; ADOLESCENT; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; SPERMATOZOON COUNT; TESTIS TUMOR;

ADOLESCENT; ADULT; ANEUPLOIDY; CROSS-SECTIONAL STUDIES; HISTONES; HUMANS; HYALURONIC ACID; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; SEMEN ANALYSIS; SPERM COUNT; SPERMATOZOA; TESTICULAR NEOPLASMS;

EID: 84906100381     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deu179     Document Type: Article

References (55)

1. Agarwal A, Allamaneni SS. Disruption of spermatogenesis by the cancer disease process. J Natl Cancer Inst Monogr 2005;34:9-12.
2. Agarwal A, Said TM. Role of sperm chromatin abnormalities and DNA damage in male infertility. Hum Reprod Update 2003;9:331-345. (Pubitemid 36987282)
3. Alvarez R, Tusell L, Genescà A, Miró R, Garcia-del-Muro X, Egozcue J. Absence of chromosomal instability in spermatozoa of men affected by testicular cancer. Hum Reprod 1999;14:247-251. (Pubitemid 29046347)
4. Auger J, Mesbah M, Huber C, Dadoune JP. Aniline blue staining as a marker of sperm chromatin defects associated with different semen characteristics discriminates between proven fertile and suspected infertile men. Int J Androl 1990;13:452-462.
5. Baker JA, Buck GM, Vena JE, Moysich KB. Fertility patterns prior to testicular cancer diagnosis. Cancer Causes Control 2005;16:295-299. (Pubitemid 40897848)
6. Berthelsen JG, Skakkebaek NE. Gonadal function in men with testis cancer. Fertil Steril 1983;39:68-75. (Pubitemid 13224246)
7. Boitrelle F, Albert M, Petit JM, Ferfouri F, Wainer R, Bergere M, Bailly M, Vialard F, Selva J. Small human sperm vacuoles observed under high magnification are pocket-like nuclear concavities linked to chromatin condensation failure. Reprod Biomed Online 2013;27:201-211.
8. Cooper TG, Noonan E, von Eckardstein S, Auger J, BakerGHW, Behre HM, Haugen TB, Kruger T, Wang C, Mbizvo MT et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update 2010;16:231-245.
9. Daugaard G, Rørth M, von der Maase H, Skakkebaek NE. Management of extragonadal germ-cell tumors and the significance of bilateral testicular biopsies. Ann Oncol 1992;3:283-289.
10. de Kretser D. Testicular cancer and infertility. BMJ 2000;321:781-782.
11. Dere E, Anderson LM, Hwang K, Boeckelheide K. Biomarkers of chemotherapy-induced testicular damage. Fertil Steril 2013;100:1192-1202.
12. Diekmann KP, Kulejewski M, Pichlmeier U, Loy V. Diagnosis of contralateral testicular intraepithelial neoplasia (TIN) in patients with testicular germ cell cancer: systematic two-site biopsies are more sensitive than a single random biopsy. Eur Urol 2007;51:175-183.
13. Dohle GR. Male infertility in cancer patients: Review of the literature. Int J Urol 2010;17:327-331.
14. Downie SE, Flaherty SP, Matthews CD. Detection of chromosomes and estimation of aneuploidy in human spermatozoa using fluorescent in situ hybridization. Mol Hum Reprod 1997;3:585-598. (Pubitemid 127512055)
15. Egozcue J, Blanco J, Vidal F. Chromosome studies in human sperm nuclei using fluorescence in situ hybridization (FISH). Hum Reprod Update 1997; 3:441-452. (Pubitemid 28069950)
16. Foresta C, Zorzi M, Rossato m, Varotto A. Sperm nuclear instability and staining with aniline blue: abnormal persistence of histones in spermatozoa in infertile men. Int J Androl 1992;15:330-337.
17. Gandini L, Lombardo F, Salacone P, Paoli D, Anselmo AP, Culasso F, Dondero F, Lenzi A. Testicular cancer and Hodgkin's disease: evaluation of semen quality. Hum Reprod 2003;18:796-801. (Pubitemid 36426959)
18. Hallak J, Kolettis PN, Sekhon VS, Thomas AJ Jr, Agarwal A. Sperm cryopreservation in patients with testicular cancer. Urology 1999; 54:894-899. (Pubitemid 29505593)
19. Hofmann N, Hilscher B. Use of aniline blue to assess chromatin condensation in morphologically normal spermatozoa in normal and infertile men. Hum Reprod 1991;6:979-982.
20. Howell SJ, Shalet SM. Testicular function following chemotherapy. Hum Reprod Update 2001;7:363-369. (Pubitemid 32655321)
21. Huszar G, JakabA, SakkasD, OzenciCC, Cayli S, Delpiano E, Ozkavukcu S. Fertility testing and ICSI sperm selection by hyaluronic acid binding: clinical and genetic aspects. Reprod Biomed Online 2007; 14:650-663.
22. Huszar G, Ozenci CC, Cayli S, Zavaczki Z, Hansch E, Vigue L. Hyaluronic acid binding by human sperm indicates cellular maturity, viability, and unreacted acrosomal status. Fertil Steril 2003;79:1616-1624. (Pubitemid 36687941)
23. Huszar G, Ozkavukcu S, Jakab A, Celik-Ozenci C, Sati GL, Cayli S. Hyaluronic acid binding ability of human sperm reflects cellular maturity and fertilizing potential: selection of sperm for intracytoplasmic sperm injection. Curr Opin Obstet Gynecol 2006;18:260-267. (Pubitemid 43864724)
24. Jacobsen R, Bostofte E, Engholm G, Hansen J, Olsen J, Skakkebaek N, Moller H. Risk of testicular cancer in men with abnormal semen characteristics: cohort study. BMJ 2000;321:789-792.
25. Jakab A, Kovacs T, Zavaczki Z, Borsos A, Bray-Ward P, Ward D, Huszar G. Efficacy of the swim-up method in eliminating sperm with diminished maturity and aneuploidy. Hum Reprod 2003;18:1481-1488. (Pubitemid 36840958)
26. Jakab A, Sakkas D, Delpiano E, Cayli S, Kovanci E, Ward D, Revelli A, Huszar G. Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies. Fertil Steril 2005;84:1665-1673. (Pubitemid 41785661)
27. Kläver R, Tüttelmann F, Bleiziffer A, Haaf T, Kliesch S, Gromoll J. DNA methylation in spermatozoa as a prospective marker in andrology. Andrology 2013;1:731-740.
28. Kliesch S, Bergmann M, Hertle L, Nieschlag E, Behre HM. Semen parameters and testicular pathology in men with testicular cancer and contralateral carcinoma in situ or bilateral testicular malignancies. Hum Reprod 1997; 12:2830-2835. (Pubitemid 28031758)
29. Kovanci E, Kovacs T, Moretti E, Vigue L, Bray-Ward P, Ward DC, Huszar G. FISH assessment of aneuploidy frequencies in mature and immature human spermatozoa classified by the absence or presence of cytoplasmic retention. Hum Reprod 2001;16:1209-1217. (Pubitemid 32544693)
30. Lass A, Akagbosu F, Brinsden P. Sperm banking and assisted reproduction treatment for couples following cancer treatment of the male partner. Hum Reprod Update 2001;7:370-377. (Pubitemid 32655322)
31. Mallidis C, Cooper TG, Hellenkemper B, Lablans M, Uckert F, Nieschlag E. Ten years' experience with an external quality control program for semen analysis. Fertil Steril 2012;98:611-621.
32. Martin R, Chernos J, Rademaker AW. The effect of cryopreservation on the frequency of chromosomal abnormalities and sex ratio in human sperm. Mol Reprod Dev 1991;30:159-163.
33. Martin RH, Ernst S, Rademaker A, Barclay L, Ko E, Summers N. Chromosomal abnormalities in sperm from testicular cancer patients before and after chemotherapy. Hum Genet 1997;99:214-218. (Pubitemid 27073325)
34. McAuliffe ME, Williams PL, Korrick SA, Dadd R, Perry MJ. The association between sperm sex chromosome disomy and semen concentration, motility and morphology. Hum Reprod 2012;27:2918-2926.
35. McDowell S, Harrison K, Kroon B, Ford E, Yazdani A. Sperm DNA fragmentation in men with malignancy. Fertil Steril 2013;99:1862-1866.
36. Meirow D, Schenker JG. Cancer and male infertility. Hum Reprod 1995; 10:2017-2022.
37. Mokanszki A, Molnar Z, Ujfalusi A, Balogh E, Bazsane ZK, Varga A, Jakab A, Olah E. Correlation study between sperm concentration, hyaluronic acid-binding capacity and sperm aneuploidy in Hungarian patients. Reprod Biomed Online 2012;25:620-626.
38. Molnar Z, Berta E, Benyo M, Poka R, Kassai BZ, Flasko T, Jakab A, Bodor M. Fertility of testicular cancer patients after anticancer treatment -experience of 11 years. Pharmazie 2014;69:437-441.
39. Ovári L, Sati L, Stronk J, Borsos A, Ward DC, Huszar G. Double probing individual human spermatozoa: aniline blue staining for persistent histones and fluorescence in situ hybridization for aneuploidies. Fertil Steril 2010;93:2255-2261.
40. Pylyp LY, Spinenko LO, Verhoglyad NV, Zukin VD. Chromosomal abnormalities in patients with oligozoospermia and non-obstructive azoospermia. J Assist Reprod Genet 2013;30:729-732.
41. Rives N, Perdrix A, Hennebicq S, Saïas-Magnan J, Melin MC, Berthaut I, Barthélémy C, Daudin M, Szerman E, Bresson JL et al. The semen quality of 1158 men with testicular cancer at the time of cryopreservation: results of the French National CECOS Network. J Androl 2012; 33:1394-1401.
42. RuixueW, Hongli Z, Zhihong Z, Rulin D, Dongfeng G, Ruizhi L. The impact of semen quality, occupational exposure to environmental factors and lifestyle on recurrent pregnancy loss. J Assist Reprod Genet 2013; 30:1513-1518.
43. Sati L, Huszar G. Methodology of aniline blue staining of chromatin and the assessment of the associated nuclear and cytoplasmic attributes in human sperm. Methods Mol Biol 2013;927:425-436.
44. Sati L, Ovari L, Bennett D, Simon SD, Demir R, Huszar G. Double probing of human spermatozoa for persistent histones, surplus cytoplasm, apoptosis and DNA fragmentation. Reprod Biomed Online 2008;16:570-579. (Pubitemid 351566172)
45. Sellami A, ChakrounN, Ben Zarrouk S, Sellami H, Kebaili S, RebaiT, Keskes L. Assessment of chromatin maturity in human spermatozoa: useful aniline blue assay for routine diagnosis of male infertility. Adv Urol 2013; 2013:578631.
46. Siva AB, Kameshwari DB, Singh V, Pavani K, Sundaram CS, Rangaraj N, Deenadayal M, Shivaji S. Proteomics-based study on asthenozoospermia: differential expression of proteasome alpha complex. Mol Hum Reprod 2010;16:452-462.
47. Spermon JR, Ramos L, Wetzels AM, Sweep CG, Braat DD, Kiemeney LA, Witjes JA. Sperm integrity pre- and post-chemotherapy in men with testicular germ cell cancer. Hum Reprod 2006;21:1781-1786. (Pubitemid 44028250)
48. Ståhl O, Eberhard J, Jepson K, Spano M, Cwikiel1 M, Cavallin-Ståhl E, Giwercman A. Sperm DNA integrity in testicular cancer patients. Hum Reprod 2006;21:3199-3205. (Pubitemid 44811624)
49. Tempest HG, Ko E, Chan P, Robaire B, Rademaker A, Martin RH. Sperm aneuploidy frequencies analysed before and after chemotherapy in testicular cancer and Hodgkin's lymphoma patients. Hum Reprod 2008; 23:251-258. (Pubitemid 351651261)
50. Trottmann M, Becker AJ, Stadler T, Straub J, Soljanik I, Schlenker B, Stief CG. Semen quality in men with malignant diseases before and after therapy and the role of cryopreservation. Eur Urol 2007;52:355-367. (Pubitemid 46963468)
51. van Casteren NJ, van Santbrink EJP, van Inzen W, Romijn JC, Dohle GR. Use rate and assisted reproduction technologies outcome of cryopreserved semen from 629 cancer patients. Fertil Steril 2008; 90:2245-2250.
52. van Casteren NJ, Boellaard WP, Romijn JC, Dohle GR. Gonadal dysfunction in male cancer patients before cytotoxic treatment. Int J Androl 2010; 33:73-79.
53. van der Steeg JW, Steures P, Eijkemans MJC, Habbema JDF, Hompes PGA, Kremer JAM, van der Leeuw-Harmsen L, Bossuyt PMM, Repping S, Silber SJ et al. Role of semen analysis in subfertile couples. Fertil Steril 2011;95:1013-1020.
54. World Health Organization.WHOLaboratory Manual for the Examination and Processing of Human Semen. 5th edn. Geneva, CH: World Health Organization, 2010.
55. Yagci A, Murk W, Stronk J, Huszar G. Spermatozoa bound to solid state hyaluronic acid show chromatin structure with high DNA chain integrity: an acridine orange fluorescence study. J Androl 2010;31: 566-572.