Cytochrome P450 system expression and DNA adduct formation in the liver of Zacco platypus following waterborne Benzo(a)pyrene exposure: Implications for biomarker determination

Environmental Toxicology

Volumn 29, Issue 9, 2014, Pages 1032-1042

  Lee, Jin Wuk ^a,b   Kim, Yong Hwa ^b   Yoon, Seokjoo ^a,b   Lee, Sung Kyu ^a,b  

^a University of Science and Technology (UST)   (South Korea)

^b Korea Institute of Toxicology   (South Korea)

Author keywords

Benzo(a)pyrene; Cytochrome P450 system; DNA adduct; Zacco platypus

Indexed keywords

DNA; PROTEINS; PYRENE; RISK ASSESSMENT; TOXICITY;

AQUATIC ENVIRONMENTS; BENZO(A)PYRENE; CYTOCHROME P450; DNA ADDUCTS; HEPATOSOMATIC INDICES; MRNA EXPRESSION LEVEL; PROTEIN EXPRESSION LEVELS; ZACCO PLATYPUS;

BIOMARKERS;

BENZO[A]PYRENE; CYTOCHROME P450 1A; MESSENGER RNA; WATER;

CYPRINID; CYTOCHROME; DNA; GENE EXPRESSION; PAH; POLLUTION EXPOSURE; PYRENE; RISK ASSESSMENT; TOXICITY; TUMOR;

ACUTE TOXICITY; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DRUG EXPOSURE; FISH; LIVER FUNCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RISK ASSESSMENT; ZACCO PLATYPUS;

ZACCO PLATYPUS;

BENZO(A)PYRENE; CYTOCHROME P450 SYSTEM; DNA ADDUCT; ZACCO PLATYPUS;

ANIMALS; BENZO(A)PYRENE; BIOLOGICAL MARKERS; CYPRINIDAE; CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; MICROSOMES, LIVER; RNA, MESSENGER; WATER POLLUTANTS, CHEMICAL;

EID: 84906088861     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.21833     Document Type: Article

References (41)

1. Anderson RO, Gutreuter SJ.1996. Length, weight, and associated structural indices. In: Murphy BR and Willis DW editors.Fisheries Techniques, 2nd edition.Bethesda, Maryland:American Fisheries Society. pp447-482.
2. Arlt VM, Stiborova M, denderson CJ, Thiemann ME, Aimova DR, Costa GD, Schmitz OJ, Farmer PB, Farmer CW, Phillips DH.2008.Metabolic activation of benzo(a)pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.Carcinogenesis29:656-665.
3. Bend JR, James MO, Dansette PM.1997.In vitro metabolism of xenobiotics in some marine animals.Ann N Y Acad Sci298:505-521.
4. Berrebi P, Boissin E, Fang F, Cattaneo-Berrebi G.2005.Intron polymorphism(EPIC-PCR) reveals phylogeographic structure of Zacco platypus in China: a possible target for aquaculture development.Heredity94:589-598.
5. 32P-postlabeling assay.Carcinogenesis12:1109-1114.
6. Curtis LR, Garzon CB, Arkoosh M, Collier T, Myers MS, Buzitis J, Hahn ME.2011.Reduced cytochrome P4501A activity and recovery from oxidative stress during subchronic benzo(a)pyrene and benzo(e)pyrene treatment of rainbow trout.Toxicol Appl Pharmacol254:1-7.
7. Denton JE.2010.Public Health Goal for Benzo(a)pyrene in Drinking Water. Public Health Goal (PHG) technical support document.Office of Environmental Health Hazard Assessment, California, US.
8. Durieus EDH, Connon RE, Werner I, D'Abronzo LS, Fitzgerald PS, Spearow JL, Ostrach DJ.2012.Cytochrome P4501A mRNA and protein induction in striped bass (Morone sasxatilis).Fish Physiol Biochem38:1107-1116; doi:10.1007/s10695-011-9597-6.
9. Greenbaum D, Colangelo C, Williams K, Gerstein M.2003.Comparing protein abundance and mRNA expression levels on a genomic scale.Genome Biol4:117-125.
10. Gygi SP, Rochon Y, Franza RB, Aebersold R.1999.Correlation between protein and mRNA abundance in yeast.Mol Cell Biol19:1720-1730.
11. Hannemann F, Bichet A, Ewen KM, Bermhardt R, 2006.Cytochrome P450 systems-biological variations of electron transport chains.Biochimica et Biophysica Acta(BBA)-General Subjects1770:330-344.
12. Haasch ML, Quardokus EM, Sutherland LA, Goodrich MS, Lech J.1993.Hepatic CYP1A1 induction in rainbow trout by continuous flowthrough exposure to β-naphthoflavone.Fundam Appl Toxicol20:72-82.
13. Hahn ME, Stegeman JJ.1994.Regulation of cytochrome P4501A1 in teleosts: sustained induction of CYP1A1 mRNA, protein, and catalytic activity by 2, 3, 7, 8-tetrachlorodibenzofuran in the marine fish Stenotomus chrysops.Toxicol Appl Pharmacol127:187-198.
14. Hawkins WE, Walker WW, Overstreet RM, Lytle TF, Lytle JS.1988.Dose-related carcinogenic effects of water-borne benzo(a)pyrene on livers of two small fish species.Ecotoxicol Environ Saf16:219-231.
15. Henderson CJ, Otto DME, Carrie D, Magnuson MA, Mclaren AW, Rosewell I, Wolf C R.2003.Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase.J Biol Chem278:13480-13486.
16. Hinton DE, Lauren DJ.1990. Liver structural alterations accompanying chrominc toxicity in fishes: potential biomarkers of exposure. In: McCarthy JF and Shugart LR, editors.Biomarkers of Environmental contamination.MI, USA:Lewis publishers. pp17-57.
17. Htun-han M.1978.The reproductive biology of the dab Limanda limanda (L) in the North Sea: gonadosomatic index, hepatosomatic index, and condition factor.J Fish Biol13:369-378.
18. Kurelec B, Krca S, Garg A, Gupta RC.1991.The potential of carp to bioactivate benzo(a)pyrene to metabolites that bind to DNA.Cancer Lett57:255-260.
19. Lee JS, Kim EY, Nomaru K, Iwata H.2011.Molecular and functional characterization of aryl hydrocarbon receptor repressor from the chicken (Gallus gallus): interspecies similarities and differences.Toxicol Sci119:319-334.
20. Levine SL, Oris JT.1999.CYP1A expression in liver and gill of rainbow trout following waterborne exposure: implications for biomarker determination.Aquat Toxicol46:279-287.
21. -ΔΔCT method.Methods25:402-408.
22. Livingstone DR.1988.Responses of microsomal NADPH-cytochrome c reductase activity and cytochrome P-450 in digestive glands of Mytilus edulis and littorina littorea to environmental and experimental exposure to pollutants.Mar Ecol46:37-43.
23. Miranda CL, Chung WG, Wang-Buhler JL, Musafia-Jeknic T, Baird WM., Buhler DR.2006.Comparative in vitro metabolism of benzo(a)pyrene by recombinant zebrafish CYP1A and liver microsomes from β-naphthoflavone-treated rainbow trout.Aquatic Toxicol80:101-108.
24. Nakata K, Tanaka Y, Nakano T, Adachi T.2006.Nuclear receptor-mediated transcriptional regulation in phaseI, II, and III xenobiotic metabolizing systems.Drug Metabol Pharmacokinet21:437-457.
25. Oh SM, Ryu BT, Kim HR, Choi KH, Chung KH.2008.Molecular cloning of CYP1A gene and its expression by Benzo(a)pyrene from Goldfish (Carassius auratus).Environ Toxicol24:225-234.
26. Omura T.2010.Structural diversity of cytochrome P450 enzyme system.J Biochem147:297-306.
27. Oost RVD, Beyer J, Vermeulen, NPE.2003.Review article fish bioaccumulation and biomarkers in environmental risk assessment: A review.Environ Toxicol Pharmacol13:57-149.
28. Østby L, Krøkje Å.2002.Cytochrome P450 (CYP1A) induction and DNA adducts in a rat hepatoma cell line (Fao), exposed to environmentally relevant concentrations of organic compounds, singly and in combinations.Environ Toxicol Pharmacol12:15-26.
29. Østby L, Gabrielsen GW, Krøkje Å.2005, Cytochrome P4501A induction and DNA adduct formation in glaucous gulls(Larus Hyperboreus) fed with environmentally contaminated gull eggs.Ecotoxicol Environ Safety62:363-375.
30. Potter D, Clarius TM, Wright AS, Watson WP.1994.Molecular dosimetry of DNA adducts in rainbow trout (Oncorhynchus mykiss) exposed to benzo(a)pyrene by different routes.Arch Toxicol69:1-7.
31. 32P-postlabeling assay for DNA adducts.Nat Protocol2:2772-2781.
32. 32P-postlabeling analysis of aromatic DNA adducts in liver and brain of wild brook trout (Salvelinus fontinalis).Chemosphere30:773-778.
33. Reynaud S, Raveton M, Ravanel P.2008.Interactions between immune and biotransformation systems in fish: a review.Aquatic Toxicology87:139-145.
34. Stiborova M, Rupertova M, Aimova D, Ryslava H, Frei E.2007.Formation and persistence of DNA adducts of anticancer drug ellipticine in rats.Toxicology236:50-60.
35. Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, Nebert DW.2004.Oral exposure to benzo(a)pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.Mol Pharmacol65:1225-1237.
36. USEPA.1991.Drinking Water Criteria Document for Polycyclic Aromatic Hydrocarbons (PAHs), Final Report, December, 1991. D.C. EPA/600/X-92/015.Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Environmental Protection Agency, Washington, US.
37. Van den Brink JM, Punt PJ, van Gorcom RFM, van den Hondel CAMJJ.2000.Regulation of expression of the Aspergillus niger benzoate para-hydroxylase cytochrome P450 system.Mol Gen Genet263:601-609.
38. Wang L, Scheffler BE, Willett KL.2006.CYP1C1 messenger RNA expression is inducible by benzo(a)pyrene in Fundulus heteroclitus embryos and adults.Toxicol Sci93:331-340.
39. Wang L, Camus AC, Dong W, Thornton C, Willett KL.2010.Expression of CYP1C1 and CYP1A in Fundulus heteroclitus during PAH-induced carcinogenesis.Aquatic Toxicol99:439-447.
40. Watson WP.1987.Review post-radiolabelling for detecting DNA damage.Mutagenesis2:319-331
41. Wozny M, Brzuzan P, Luczynski MK, Gora M, Wolinska L, Bukowski R, Podlasz P.2010.CYP1A expression in liver and gills of rainbow trout (Oncorhynchus mykiss) after short-term exposure to dibenzothiophene (DBT).Chemosphere79:110-112.