메뉴 건너뛰기




Volumn 52, Issue 9, 2014, Pages 1170-1178

Computational analysis of benzofuran-2-carboxlic acids as potent Pim-1 kinase inhibitors

Author keywords

Cancer and inhibitor; Molecular docking; Pim kinase

Indexed keywords

BENZOFURAN 2 CARBOXYLIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; PROTEIN KINASE INHIBITOR; PROTEIN KINASE PIM 1; UNCLASSIFIED DRUG; BENZOFURAN DERIVATIVE; CARBOXYLIC ACID; LIGAND;

EID: 84906053714     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2014.880488     Document Type: Article
Times cited : (22)

References (17)
  • 1
    • 3343007095 scopus 로고    scopus 로고
    • Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Serl 12 gatekeeper site
    • Aho TLT, Sandholm J, Peltola KJ, et al. (2004). Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Serl 12 gatekeeper site. FEBS Lett 571:43-9.
    • (2004) FEBS Lett , vol.571 , pp. 43-49
    • Aho, T.L.T.1    Sandholm, J.2    Peltola, K.J.3
  • 2
    • 0030829781 scopus 로고    scopus 로고
    • Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc
    • Allen JD, Verhoeven E, Domen J, et al. (1997). Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. Oncogene 15:1133-41.
    • (1997) Oncogene , vol.15 , pp. 1133-1141
    • Allen, J.D.1    Verhoeven, E.2    Domen, J.3
  • 3
    • 26444448463 scopus 로고    scopus 로고
    • The survival kinases Akt and Pim as potential pharmacological targets
    • Amaravadi R, Thompson CB. (2005). The survival kinases Akt and Pim as potential pharmacological targets. J Clin Invest 115:2618-24.
    • (2005) J Clin Invest , vol.115 , pp. 2618-2624
    • Amaravadi, R.1    Thompson, C.B.2
  • 5
    • 33644779115 scopus 로고    scopus 로고
    • Overexpression of Pim-1 during progression of prostatic adenocarcinoma
    • Cibull TL, Jones TD, Li L, et al. (2006). Overexpression of Pim-1 during progression of prostatic adenocarcinoma. J Clin Pathol 59:285-8.
    • (2006) J Clin Pathol , vol.59 , pp. 285-288
    • Cibull, T.L.1    Jones, T.D.2    Li, L.3
  • 6
    • 26644434368 scopus 로고    scopus 로고
    • Pim-2 upregulation: Biological implications associated with disease progression and perinueral invasion in prostate cancer
    • Dai H, Li R, Wheeler T, et al. (2005). Pim-2 upregulation: Biological implications associated with disease progression and perinueral invasion in prostate cancer. Prostate 65:276-86.
    • (2005) Prostate , vol.65 , pp. 276-286
    • Dai, H.1    Li, R.2    Wheeler, T.3
  • 7
    • 0034708236 scopus 로고    scopus 로고
    • Developmental expression of pim kinases suggests functions also outside of the hematopoietic system
    • Eichmann A, Yuan L, Breant C, et al. (2000). Developmental expression of pim kinases suggests functions also outside of the hematopoietic system. Oncogene 19:1215-24.
    • (2000) Oncogene , vol.19 , pp. 1215-1224
    • Eichmann, A.1    Yuan, L.2    Breant, C.3
  • 8
    • 36749044271 scopus 로고    scopus 로고
    • Importance of molecular computer modeling in anticancer drug development
    • Geromichalos GD. (2007). Importance of molecular computer modeling in anticancer drug development. J BUON 1:S101-18.
    • (2007) J BUON , vol.1
    • Geromichalos, G.D.1
  • 9
    • 33746122005 scopus 로고    scopus 로고
    • Pim-3, a proto-oncogene with serin/theronine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines
    • Li YY, Popivanova BK, Nagai Y, et al. (2006). Pim-3, a proto-oncogene with serin/theronine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines. Cancer Res 66: 6741-7.
    • (2006) Cancer Res , vol.66 , pp. 6741-6747
    • Li, Y.Y.1    Popivanova, B.K.2    Nagai, Y.3
  • 10
    • 48549096958 scopus 로고    scopus 로고
    • Pim kinases promote cell cycle progression by phosphorylating and downregulating p27KipI at the transcriptional and posttranscriptional levels
    • Morishita D, Katayama R, Sekimizu K, et al. (2008). Pim kinases promote cell cycle progression by phosphorylating and downregulating p27KipI at the transcriptional and posttranscriptional levels. Cancer Res 68:5076-85.
    • (2008) Cancer Res , vol.68 , pp. 5076-5085
    • Morishita, D.1    Katayama, R.2    Sekimizu, K.3
  • 11
    • 78951468972 scopus 로고    scopus 로고
    • Cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase
    • Morishita D, Takami M, Yoshikawa S, et al. (2011). Cell-permeable carboxyl-terminal p27Kip1 peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase. J Biol Chem 286:2681-8.
    • (2011) J Biol Chem , vol.286 , pp. 2681-2688
    • Morishita, D.1    Takami, M.2    Yoshikawa, S.3
  • 12
    • 78650606450 scopus 로고    scopus 로고
    • For better or for worse: The role of Pim oncogenes in tumorigenesis
    • Nawijn MC, Alendar A, Berns A. (2011). For better or for worse: The role of Pim oncogenes in tumorigenesis. Nat Rav Cancer 11:23-34.
    • (2011) Nat Rav Cancer , vol.11 , pp. 23-34
    • Nawijn, M.C.1    Alendar, A.2    Berns, A.3
  • 13
    • 33846701190 scopus 로고    scopus 로고
    • Proto-oncogenes, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in colon cancer cells and can prevent Bad-mediated apoptosis
    • Popivanova BK, Li YY, Zheng H, et al. (2007). Proto-oncogenes, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in colon cancer cells and can prevent Bad-mediated apoptosis. Cancer Sci 98: 321-8.
    • (2007) Cancer Sci , vol.98 , pp. 321-328
    • Popivanova, B.K.1    Li, Y.Y.2    Zheng, H.3
  • 14
    • 84862986683 scopus 로고    scopus 로고
    • Pim kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer
    • Siu A, Virtanen C, Jongstra J. (2011). Pim kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer. Oncotarget 2:1134-44.
    • (2011) Oncotarget , vol.2 , pp. 1134-1144
    • Siu, A.1    Virtanen, C.2    Jongstra, J.3
  • 15
    • 84895768815 scopus 로고    scopus 로고
    • Molecular docking study of P4-benzoxaborole substituted ligands as inhibitors of HCV NS3/4A protease
    • Wadood A, Riaz M, Jamal SB, et al. (2013). Molecular docking study of P4-benzoxaborole substituted ligands as inhibitors of HCV NS3/4A protease. Bioinformation 9:309-14.
    • (2013) Bioinformation , vol.9 , pp. 309-314
    • Wadood, A.1    Riaz, M.2    Jamal, S.B.3
  • 16
    • 77951092205 scopus 로고    scopus 로고
    • Accelerated hepatocellular carcinoma development in mice expression the Pim-3 transgene selectively in the liver
    • Wu Y, Wang YY, Nakamota Y, et al. (2010). Accelerated hepatocellular carcinoma development in mice expression the Pim-3 transgene selectively in the liver. Oncogene 29:2228-37.
    • (2010) Oncogene , vol.29 , pp. 2228-2237
    • Wu, Y.1    Wang, Y.Y.2    Nakamota, Y.3
  • 17
    • 79955556964 scopus 로고    scopus 로고
    • The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
    • Xiang Y, Hirth B, Asmussen G, et al. (2011). The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors. Bioorg Med Chem Lett 21:3050-6.
    • (2011) Bioorg Med Chem Lett , vol.21 , pp. 3050-3056
    • Xiang, Y.1    Hirth, B.2    Asmussen, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.