Geometrical confinement of Gd(DOTA) molecules within mesoporous silicon nanoconstructs for MR imaging of cancer

Cancer Letters

Volumn 352, Issue 1, 2014, Pages 97-101

  Gizzatov, Ayrat ^a,b   Stigliano, Cinzia ^a   Ananta, Jeyerama S ^a   Sethi, Richa ^b   Xu, Rong ^a   Guven, Adem ^b   Ramirez, Maricela ^a   Shen, Haifa ^a   Sood, Anil ^c   Ferrari, Mauro ^a,d   Wilson, Lon J ^b   Liu, Xuewu ^a   Decuzzi, Paolo ^a  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b RICE UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Magnetic Resonance Imaging; Mesoporous silicon; Nanoconstructs; Relaxivity

Indexed keywords

3 AMINOPROPYLTRIETHOXYSILANE; GADOLINIUM; GADOLINIUM TETRAAZACYCLODODECANE TETRAACETIC ACID; MICROSPHERE; SILICON MICROSPHERE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BREAST CANCER; CANCER CELL; CHELATION; CHEMICAL STRUCTURE; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMAGE QUALITY; IMAGING PHANTOM; MELANOMA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SCANNER; OVARY CANCER; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; SHORT SURVEY; SURFACE PROPERTY; TUMOR VASCULARIZATION; TUMOR VOLUME;

MAGNETIC RESONANCE IMAGING; MESOPOROUS SILICON; NANOCONSTRUCTS; RELAXIVITY;

CONTRAST MEDIA; HETEROCYCLIC COMPOUNDS; HUMANS; MAGNETIC RESONANCE IMAGING; MOLECULAR STRUCTURE; NANOPARTICLES; NEOPLASMS; ORGANOMETALLIC COMPOUNDS; POROSITY; SILICON;

EID: 84906046525     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.06.001     Document Type: Review

References (28)

1. Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 2005, 5:161-171.
2. Schroeder A., Heller D.A., Winslow M.M., Dahlman J.E., Pratt G.W., Langer R., Jacks T., Anderson D.G. Treating metastatic cancer with nanotechnology. Nat. Rev. Cancer 2012, 12:39-50.
3. Davis M.E., Chen Z.G., Shin D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 2008, 7:771-782.
4. Gabizon A., Catane R., Uziely B., Kaufman B., Safra T., Cohen R., Martin F., Huang A., Barenholz Y. Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 1994, 54:987-992.
5. Gradishar W.J., Tjulandin S., Davidson N., Shaw H., Desai N., Bhar P., Hawkins M., O'Shaughnessy J. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J. Clin. Oncol. 2005, 23:7794-7803.
6. Lauffer R.B., Parmelee D.J., Dunham S.U., Ouellet H.S., Dolan R.P., Witte S., McMurry T.J., Walovitch R.C. MS-325: albumin-targeted contrast agent for MR angiography. Radiology 1998, 207:529-538.
7. Etheridge M.L., Campbell S.A., Erdman A.G., Haynes C.L., Wolf S.M., McCullough J. The big picture on nanomedicine: the state of investigational and approved nanomedicine products. Nanomedicine 2013, 9:1-14.
8. van de Ven A.L., Kim P., Haley O., Fakhoury J.R., Adriani G., Schmulen J., Moloney P., Hussain F., Ferrari M., Liu X., Yun S.H., Decuzzi P. Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution. J. Control. Release 2012, 158:148-155.
9. Decuzzi P., Pasqualini R., Arap W., Ferrari M. Intravascular delivery of particulate systems: does geometry really matter?. Pharm. Res. 2009, 26:235-243.
10. Peer D., Karp J.M., Hong S., Farokhzad O.C., Margalit R., Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat. Nanotechnol. 2007, 2:751-760.
11. Key J., Aryal S., Gentile F., Ananta J.S., Zhong M., Landis M.D., Decuzzi P. Engineering discoidal polymeric nanoconstructs with enhanced magneto-optical properties for tumor imaging. Biomaterials 2013, 34:5402-5410.
12. Jain R.K., Stylianopoulos T. Delivering nanomedicine to solid tumors. Nat. Rev. Clin. Oncol. 2010, 7:653-664.
13. Hobbs S.K., Monsky W.L., Yuan F., Roberts W.G., Griffith L., Torchilin V.P., Jain R.K. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc. Natl. Acad. Sci. USA 1998, 95:4607-4612.
14. Chen X., Tohme M., Park R., Hou Y., Bading J.R., Conti P.S. Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide. Mol. Imaging 2004, 3:96-104.
15. Lee T.R., Choi M., Kopacz A.M., Yun S.H., Liu W.K., Decuzzi P. On the near-wall accumulation of injectable particles in the microcirculation: smaller is not better. Sci. Rep. 2013, 3:2079.
16. van de Ven A.L., Kim P., Haley O., Fakhoury J.R., Adriani G., Schmulen J., Moloney P., Hussain F., Ferrari M., Liu X., Yun S.H., Decuzzi P. Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution. J. Control Release 2011.
17. Lee S.Y., Ferrari M., Decuzzi P. Shaping nano-/micro-particles for enhanced vascular interaction in laminar flows. Nanotechnology 2009, 20:495101.
18. Lee S.Y., Ferrari M., Decuzzi P. Design of bio-mimetic particles with enhanced vascular interaction. J. Biomech. 2009, 42:1885-1890.
19. Godin B., Chiappini C., Srinivasan S., Alexander J.F., Yokoi K., Ferrari M., Decuzzi P., Liu X. Discoidal porous silicon particles: fabrication and biodistribution in breast cancer bearing mice. Adv. Funct. Mater. 2012, 22:4225-4235.
20. Decuzzi P., Godin B., Tanaka T., Lee S.Y., Chiappini C., Liu X., Ferrari M. Size and shape effects in the biodistribution of intravascularly injected particles. J. Control. Release 2010, 141:320-327.
21. Blanco E., Sangai T., Hsiao A., Ferrati S., Bai L., Liu X., Meric-Bernstam F., Ferrari M. Multistage delivery of chemotherapeutic nanoparticles for breast cancer treatment. Cancer Lett. 2013, 334:245-252.
22. Shen H., Mittal V., Ferrari M., Chang J. Delivery of gene silencing agents for breast cancer therapy. Breast Cancer Res. 2013, 15:205.
23. Shen H., Rodriguez-Aguayo C., Xu R., Gonzalez-Villasana V., Mai J., Huang Y., Zhang G., Guo X., Bai L., Qin G., Deng X., Li Q., Erm D.R., Aslan B., Liu X., Sakamoto J., Chavez-Reyes A., Han H.D., Sood A.K., Ferrari M., Lopez-Berestein G. Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery. Clin. Cancer Res. 2013, 19:1806-1815.
24. Ananta J.S., Godin B., Sethi R., Moriggi L., Liu X., Serda R.E., Krishnamurthy R., Muthupillai R., Bolskar R.D., Helm L., Ferrari M., Wilson L.J., Decuzzi P. Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast. Nat. Nanotechnol. 2010, 5:815-821.
25. Sethi R., Ananta J.S., Karmonik C., Zhong M., Fung S.H., Liu X., Li K., Ferrari M., Wilson L.J., Decuzzi P. Enhanced MRI relaxivity of Gd(3+) -based contrast agents geometrically confined within porous nanoconstructs. Contrast Media Mol. Imaging 2012, 7:501-508.
26. Laurent S., Elst L.V., Muller R.N. Comparative study of the physicochemical properties of six clinical low molecular weight gadolinium contrast agents. Contrast Media Mol. Imaging 2006, 1:128-137.
27. Lauffer R.B. Paramagnetic metal-complexes as water proton relaxation agents for NMR imaging - theory and design. Chem. Rev. 1987, 87:901-927.
28. Godin B., Gu J., Serda R.E., Bhavane R., Tasciotti E., Chiappini C., Liu X., Tanaka T., Decuzzi P., Ferrari M. Tailoring the degradation kinetics of mesoporous silicon structures through PEGylation. J. Biomed. Mater. Res. A 2010, 94:1236-1243.