Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription

Journal of Biological Chemistry

Volumn 289, Issue 33, 2014, Pages 22723-22738

  Ilinykh, Philipp A ^a,b   Tigabu, Bersabeh ^a,b   Ivanov, Andrey ^c   Ammosova, Tatiana ^c,d   Obukhov, Yuri ^c   Garron, Tania ^a,b   Kumari, Namita ^c   Kovalskyy, Dmytro ^f,g   Platonov, Maxim O ^f,g   Naumchik, Vasiliy S ^f,g   Freiberg, Alexander N ^a,b   Nekhai, Sergei ^c,d,e   Bukreyev, Alexander ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b Galveston National Laboratory   (United States)

^c HOWARD UNIVERSITY   (United States)

^d HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e HOWARD UNIVERSITY   (United States)

^f TARAS SHEVCHENKO NATIONAL UNIVERSITY OF KYIV   (Ukraine)

^g ENAMINE LTD   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CYTOLOGY; DISEASES; MOLECULES; NUCLEIC ACIDS; PHOSPHATASES; PHOSPHORYLATION; POLYMERS; PROTEINS; VIRUSES;

DEPHOSPHORYLATIONS; HOST CELL PROTEIN; POLYMERASE ACTIVITIES; POLYMERASE COMPLEX; PROTEIN PHOSPHATASE-1; REGULATORY SUBUNITS; THREONINE RESIDUES; VIRAL TRANSCRIPTION;

TRANSCRIPTION;

1E7 03; MESSENGER RNA; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN VP30; SERINE; SHORT HAIRPIN RNA; THREONINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; ANTIVIRUS AGENT; DNA DIRECTED RNA POLYMERASE; TRANSCRIPTION FACTOR; VIRAL PROTEIN; VIRUS RNA; VP30 PROTEIN, EBOLA VIRUS;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; EBOLA VIRUS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN TARGETING; VIRUS GENOME; VIRUS REPLICATION; VIRUS TRANSCRIPTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; EBOLAVIRUS; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; VERO CELL LINE;

ANIMALS; ANTIVIRAL AGENTS; DNA-DIRECTED RNA POLYMERASES; EBOLAVIRUS; HUMANS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; RNA, MESSENGER; RNA, VIRAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VERO CELLS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84905993894     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.575050     Document Type: Article

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