Identification of apoptotic cells in the thymus of piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus

Virus Research

Volumn 189, Issue , 2014, Pages 29-33

  Li, Yuming ^a,b   Wang, Gang ^a   Liu, Yonggang ^a   Tu, Yabin ^a   He, Yuli ^a   Wang, Zhiyan ^a   Han, Zifeng ^a,b   Li, Li ^a   Li, Aidong ^a   Tao, Ye ^a   Cai, Xuehui ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

Author keywords

Apoptotic cells; Highly pathogenic PRRSV; Thymus

Indexed keywords

CD14 ANTIGEN; FLUORESCEIN ISOTHIOCYANATE; MONOCLONAL ANTIBODY; CD3 ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTERIVIRUS; ARTICLE; CD3+ T LYMPHOCYTE; EPITHELIUM CELL; NONHUMAN; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PRIORITY JOURNAL; SWINE; THYMUS; VIRUS VIRULENCE; ANIMAL; ATROPHY; CHEMISTRY; ISOLATION AND PURIFICATION; PATHOLOGY; PHYSIOLOGY; THYMOCYTE; VIROLOGY;

ANIMALS; ANTIGENS, CD3; APOPTOSIS; ATROPHY; EPITHELIAL CELLS; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SWINE; THYMOCYTES; THYMUS GLAND;

EID: 84905977561     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2014.04.011     Document Type: Article

References (19)

1. Benson J.E., Yaeger M.J., Christopher-Hennings J., Lager K., Yoon K.-J. A comparison of virus isolation, immunohistochemistry, fetal serology, and reverse-transcription polymerase chain reaction assay for the identification of porcine reproductive and respiratory syndrome virus transplacental infection in the fetus. J. Vet. Diagn. Invest. 2002, 14(1):8-14.
2. Cavanagh D. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 1997, 142(3):629.
3. Chen J., Liu T., Zhu C.G., Jin Y.F., Zhang Y.Z. Genetic variation of Chinese PRRSV strains based on ORF5 sequence. Biochem. Genet. 2006, 44(9-10):425-435.
4. Choi C., Chae C. Expression of tumour necrosis factor-α is associated with apoptosis in lungs of pigs experimentally infected with porcine reproductive and respiratory syndrome virus. Res. Vet. Sci. 2002, 72(1):45-49.
5. Feng W.H., Tompkins M.B., Xu J.S., Brown T.T., Laster S.M., Zhang H.X., McCaw M.B. Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus. Virology 2002, 302(2):363-372.
6. He Y., Wang G., Liu Y., Shi W., Han Z., Wu J., Jiang C., Wang S., Hu S., Wen H., Dong J., Liu H., Cai X. Characterization of thymus atrophy in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus. Vet. Microbiol. 2012, 160(3-4):455-462.
7. Li Y., Wang X., Bo K., Wang X., Tang B., Yang B., Jiang W., Jiang P. Emergence of a highly pathogenic porcine reproductive and respiratory syndrome virus in the Mid-Eastern region of China. Vet. J. 2007, 174(3):577-584.
8. Lu J.J.-Y., Chen J.-Y., Hsu T.-Y., Winston C., Su I.-J., Yang C.-S. Induction of apoptosis in epithelial cells by Epstein-Barr virus latent membrane protein 1. J. Gen. Virol. 1996, 77(8):1883-1892.
9. Nagata S. Apoptosis by death factor review. Cell 1997, 88(355-365):392.
10. Pearse G. Normal structure, function and histology of the thymus. Toxicol. Pathol. 2006, 34(5):504-514.
11. Polson D.D., Marsh W.E., Dial G.D. Financial evaluation and decision making in the swine breeding herd. Vet. Clin. North Am. 1992, 8(3):725-747.
12. Rowland R.R. The interaction between PRRSV and the late gestation pig fetus. Virus Res. 2010, 154(1):114-122.
13. Sur J.-H., Doster A., Osorio F. Apoptosis induced in vivo during acute infection by porcine reproductive and respiratory syndrome virus. Vet. Pathol. 1998, 35(6):506-514.
14. Thanawongnuwech R., Thacker E.L., Halbur P.G. Effect of porcine reproductive and respiratory syndrome virus (PRRSV) (isolate ATCC VR-2385) infection on bactericidal activity of porcine pulmonary intravascular macrophages (PIMs): in vitro comparisons with pulmonary alveolar macrophages (PAMs). Vet. Immunol. Immunopathol. 1997, 59(3):323-335.
15. Tian K., Yu X., Zhao T., Feng Y., Cao Z., Wang C., Hu Y., Chen X., Hu D., Tian X., Liu D., Zhang S., Deng X., Ding Y., Yang L., Zhang Y., Xiao H., Qiao M., Wang B., Hou L., Wang X., Yang X., Kang L., Sun M., Jin P., Wang S., Kitamura Y., Yan J., Gao G.F. Emergence of fatal PRRSV variants: unparalleled outbreaks of atypical PRRS in China and molecular dissection of the unique hallmark. PLoS ONE 2007, 2(6):e526.
16. Tong G.Z., Zhou Y.J., Hao X.F., Tian Z.J., An T.Q., Qiu H.J. Highly pathogenic porcine reproductive and respiratory syndrome, China. Emerg. Infect. Dis. 2007, 13(9):1434-1436.
17. Wang G., He Y., Tu Y., Liu Y., Zhou E.M., Han Z., Jiang C., Wang S., Shi W., Cai X. Comparative analysis of apoptotic changes in peripheral immune organs and lungs following experimental infection of piglets with highly pathogenic and classical porcine reproductive and respiratory syndrome virus. Virol. J. 2014, 11(1):2.
18. Wang G., Song T., Yu Y., Liu Y., Shi W., Wang S., Rong F., Dong J., Liu H., Cai X., Zhou E.M. Immune responses in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus. Vet. Immunol. Immunopathol. 2011, 142(3-4):170-178.
19. Zheng L., Fisher G., Miller R.E., Peschon J., Lynch D.H., Lenardo M.J. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 1995, 377(6547):348-351.