Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 32, 2014, Pages 11828-11833

  Lee, Seung Eun ^a,b,c   Lee, Jaekwang ^b   Latchoumane, Charles ^a   Lee, Boyoung ^a   Oh, Soo Jin ^b   Saud, Zahangir Alam ^b,g   Park, Cheongdahm ^b   Sun, Ning ^d   Cheong, Eunji ^e   Chen, Chien Chang ^f   Choi, Eui Ju ^c   Lee, C Justin ^b   Shin, Hee Sup ^a  

^a Institute for Basic Science   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Korea University   (South Korea)

^d AMGEN INC   (United States)

^e Yonsei University   (South Korea)

^f INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^g UNIVERSITY OF RAJSHAHI   (Bangladesh)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL CAV3.2; CALCIUM CHANNEL CAV3.3; CALCIUM CHANNEL T TYPE; GAMMA BUTYROLACTONE; MESSENGER RNA; UNCLASSIFIED DRUG;

ABSENCE SEIZURE; ACTION POTENTIAL; AFTERHYPERPOLARIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPILEPTIC DISCHARGE; GENE DELETION; GENE SILENCING; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPOLARIZATION; RHYTHMIC BURST DISCHARGE; SEIZURE; SPIKE AND WAVE DISCHARGE; SYNAPTIC TRANSMISSION; THALAMOCORTICAL TRACT; THALAMUS RETICULAR NUCLEUS;

4-BUTYROLACTONE; ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS, T-TYPE; DISEASE MODELS, ANIMAL; ELECTROPHYSIOLOGICAL PHENOMENA; EPILEPSY, ABSENCE; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PATCH-CLAMP TECHNIQUES; THALAMIC NUCLEI;

EID: 84905967103     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1408609111     Document Type: Article

References (40)

1. Crunelli V, Leresche N (2002) Childhood absence epilepsy: Genes, channels, neurons and networks. Nat Rev Neurosci 3(5):371-382
2. Steriade M, Deschênes M, Domich L, Mulle C (1985) Abolition of spindle oscillations in thalamic neurons disconnected from nucleus reticularis thalami. J Neurophysiol 54(6): 1473-1497
3. Steriade M, McCormick DA, Sejnowski TJ (1993) Thalamocortical oscillations in the sleeping and aroused brain. Science 262(5134):679-685
4. Huntsman MM, Porcello DM, Homanics GE, DeLorey TM, Huguenard JR (1999) Reciprocal inhibitory connections and network synchrony in the mammalian thalamus. Science 283(5401):541-543
5. Jones EG (2002) Thalamic circuitry and thalamocortical synchrony. Philos Trans R Soc Lond B Biol Sci 357(1428):1659-1673
6. Steriade M, Llinás RR (1988) The functional states of the thalamus and the associated neuronal interplay. Physiol Rev 68(3):649-742
7. Sherman SM, Guillery RW (2002) The role of the thalamus in the flow of information to the cortex. Philos Trans R Soc Lond B Biol Sci 357(1428):1695-1708
8. Fonnum F, Storm-Mathisen J, Divac I (1981) Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain. Neuroscience 6(5):863-873
9. Houser CR, Vaughn JE, Barber RP, Roberts E (1980) GABA neurons are the major cell type of the nucleus reticularis thalami. Brain Res 200(2):341-354
10. Huguenard JR, McCormick DA (2007) Thalamic synchrony and dynamic regulation of global forebrain oscillations. Trends Neurosci 30(7):350-356
11. von Krosigk M, Bal T, McCormick DA (1993) Cellular mechanisms of a synchronized oscillation in the thalamus. Science 261(5119):361-364
12. McCormick DA, Bal T (1997) Sleep and arousal: Thalamocortical mechanisms. Annu Rev Neurosci 20:185-215
13. Jahnsen H, Llinás R (1984) Electrophysiological properties of guinea-pig thalamic neurones: An in vitro study. J Physiol 349:205-226
14. Contreras D, Curró Dossi R, Steriade M (1993) Electrophysiological properties of cat reticular thalamic neurones in vivo. J Physiol 470:273-294
15. Perez-Reyes E (2003) Molecular physiology of low-voltage-activated t-type calcium channels. Physiol Rev 83(1):117-161
16. Perez-Reyes E, et al. (1998) Molecular characterization of a neuronal low-voltageactivated T-type calcium channel. Nature 391(6670):896-900
17. Talley EM, et al. (1999) Differential distribution of three members of a gene family encoding low voltage-activated (T-type) calcium channels. J Neurosci 19(6):1895-1911
18. Bal T, von Krosigk M, McCormick DA (1995) Synaptic and membrane mechanisms underlying synchronized oscillations in the ferret lateral geniculate nucleus in vitro. J Physiol 483(Pt 3):641-663
19. Deschêenes M, Hu B (1990) Electrophysiology and pharmacology of the corticothalamic input to lateral thalamic nuclei: An intracellular study in the cat. Eur J Neurosci 2(2):140-152
20. Manning JP, Richards DA, Leresche N, Crunelli V, Bowery NG (2004) Cortical-area specific block of genetically determined absence seizures by ethosuximide. Neuroscience 123(1):5-9
21. Avanzini G, Vergnes M, Spreafico R, Marescaux C (1993) Calcium-dependent regulation of genetically determined spike and waves by the reticular thalamic nucleus of rats. Epilepsia 34(1):1-7
22. Astori S, et al. (2011) The Ca(V)3.3 calcium channel is the major sleep spindle pacemaker in thalamus. Proc Natl Acad Sci USA 108(33):13823-13828
23. Cueni L, et al. (2008) T-type Ca2+ channels, SK2 channels and SERCAs gate sleeprelated oscillations in thalamic dendrites. Nat Neurosci 11(6):683-692
24. Steriade M, Domich L, Oakson G (1986) Reticularis thalami neurons revisited: Activity changes during shifts in states of vigilance. J Neurosci 6(1):68-81
25. Kim U, Sanchez-Vives MV, McCormick DA (1997) Functional dynamics of GABAergic inhibition in the thalamus. Science 278(5335):130-134
26. Meeren HK, Veening JG, Möderscheim TA, Coenen AM, van Luijtelaar G (2009) Thalamic lesions in a genetic rat model of absence epilepsy: Dissociation between spike-wave discharges and sleep spindles. Exp Neurol 217(1):25-37
27. Eckle VS, et al. (2014) Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility. J Physiol 592(Pt 4):795-809
28. Chioza B, et al. (2006) Evaluation of CACNA1H in European patients with childhood absence epilepsy. Epilepsy Res 69(2):177-181
29. Chen Y, et al. (2003) Association between genetic variation of CACNA1H and childhood absence epilepsy. Ann Neurol 54(2):239-243
30. Ernst WL, Zhang Y, Yoo JW, Ernst SJ, Noebels JL (2009) Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy. J Neurosci 29(6):1615-1625
31. Song I, et al. (2004) Role of the alpha1G T-type calcium channel in spontaneous absence seizures in mutant mice. J Neurosci 24(22):5249-5257
32. Snead OC, 3rd (1991) The gamma-hydroxybutyrate model of absence seizures: Correlation of regional brain levels of gamma-hydroxybutyric acid and gamma-butyrolactone with spike wave discharges. Neuropharmacology 30(2):161-167
33. Banerjee PK, Snead OC, 3rd (1995) Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): A possible mechanism for the generation of absence-like seizures induced by GHB. J Pharmacol Exp Ther 273(3): 1534-1543
34. Tóth TI, Bessaïh T, Leresche N, Crunelli V (2007) The properties of reticular thalamic neuron GABA(A) IPSCs of absence epilepsy rats lead to enhanced network excitability. Eur J Neurosci 26(7):1832-1844
35. Lacey CJ, Bryant A, Brill J, Huguenard JR (2012) Enhanced NMDA receptor-dependent thalamic excitation and network oscillations in stargazer mice. J Neurosci 32(32): 11067-11081
36. Anderson D, et al. (2010) Regulation of the KV4.2 complex by CaV3.1 calcium channels. Channels (Austin) 4(3):163-167
37. Xiong H, Kovacs I, Zhang Z (2004) Differential distribution of KChIPs mRNAs in adult mouse brain. Brain Res Mol Brain Res 128(2):103-111
38. Engbers JD, et al. (2012) Intermediate conductance calcium-activated potassium channels modulate summation of parallel fiber input in cerebellar Purkinje cells. Proc Natl Acad Sci USA 109(7):2601-2606
39. Cope DW, et al. (2009) Enhanced tonic GABAA inhibition in typical absence epilepsy. Nat Med 15(12):1392-1398
40. Walker MC, Kullmann DM (2012) Tonic GABAA receptor-mediated signaling in epilepsy. Jasper's Basic Mechanisms of the Epilepsies, eds Noebels JL, Massimo A, Rogawski M, Olsen R, Delgado-Escueta A (Oxford Univ Press, New York), 4th Ed.