Synthesis and biological evaluation of 9α- and 9β-hydroxyamino- parthenolides as novel anticancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 16, 2014, Pages 4014-4018

  Moumou, Mohamed ^a   El Bouakher, Abderrahman ^a,e   Allouchi, Hassan ^b   El Hakmaoui, Ahmed ^a   Benharref, Ahmed ^c   Mathieu, Véronique ^d   Guillaumet, Gérald ^e   Akssira, Mohamed ^a  

^a HASSAN II UNIVERSITY   (Morocco)

^b UNIVERSITÉ DE TOURS   (France)

^c FACULTÉ DES SCIENCES SEMLALIA   (Morocco)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^e UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

9 Hydroxyamino parthenolides; 9 Hydroxyparthenolides; 9 Hydroxy 1 ,10 epoxyparthenolides; 9 Hydroxy 1 ,10 epoxyamino parthenolides; Anticancer activity

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; PARTHENOLIDE; SESQUITERPENE;

ANIMAL; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HUMAN; MCF 7 CELL LINE; MOUSE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

AMINES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MCF-7 CELLS; MICE; MOLECULAR CONFORMATION; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84905922656     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.06.019     Document Type: Article

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