Synthesis and evaluation of triazole linked glycosylated 18β-glycyrrhetinic acid derivatives as anticancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 16, 2014, Pages 3865-3868

  Parida, Pravat Kumar ^a   Sau, Abhijit ^a   Ghosh, Tamashree ^a   Jana, Kuladip ^a   Biswas, Kaushik ^a   Raha, Sanghamitra ^b   Misra, Anup Kumar ^a  

^a BOSE INSTITUTE   (India)

^b VISVA BHARATI UNIVERSITY   (India)

Author keywords

18 Glycyrrhetinic acid; Anticancer agent; Carbohydrate; Click chemistry; Triazole

Indexed keywords

18ALPHA-GLYCYRRHETINIC ACID; ANTINEOPLASTIC AGENT; GLYCYRRHETINIC ACID; TRIAZOLE DERIVATIVE; 18BETA GLYCYRRHETINIC ACID PROPARGYL ESTER; AZIDE; CARBOHYDRATE; GLYCYRRHETINIC ACID DERIVATIVE; HYDROXYL GROUP; RESVERATROL; TERPENOID DERIVATIVE; TRIAZOLE; UNCLASSIFIED DRUG;

ANALOGS AND DERIVATIVES; CELL LINE; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; GLYCOSYLATION; HELA CELL LINE; HUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARBOHYDRATE ANALYSIS; CLICK CHEMISTRY; CONTROLLED STUDY; CROSS LINKING; CYCLOADDITION; DRUG ACETYLATION; DRUG SYNTHESIS; EPITHELIUM CELL; FEMALE; HUMAN CELL; IC50; IN VITRO STUDY; KIDNEY EPITHELIUM;

ANTINEOPLASTIC AGENTS; CELL LINE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GLYCOSYLATION; GLYCYRRHETINIC ACID; HELA CELLS; HUMANS; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84905905997     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.06.054     Document Type: Article

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