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Volumn 16, Issue 10, 2014, Pages

The Significance of Mixed States in Depression and Mania

Author keywords

Bipolar disorder; Hypomania depression; Major depressive disorder; Mania; Mixed features; Mixed state

Indexed keywords


EID: 84905889561     PISSN: 15233812     EISSN: 15351645     Source Type: Journal    
DOI: 10.1007/s11920-014-0486-4     Document Type: Review
Times cited : (30)

References (102)
  • 2
    • 0015449445 scopus 로고
    • Depression during mania: clinical observations and theoretical implications
    • PID: 4638717, COI: 1:STN:280:DyaE3s%2FlsVeitA%3D%3D
    • Kotin J, Goodwin FK. Depression during mania: clinical observations and theoretical implications. Am J Psychiatry. 1972;129(6):679–86.
    • (1972) Am J Psychiatry , vol.129 , Issue.6 , pp. 679-686
    • Kotin, J.1    Goodwin, F.K.2
  • 3
    • 0017103746 scopus 로고
    • Incidence and signficiance of mixed affective states in a bipolar population
    • PID: 962490, COI: 1:STN:280:DyaE283ns12msg%3D%3D
    • Himmelhoch JM et al. Incidence and signficiance of mixed affective states in a bipolar population. Arch Gen Psychiatry. 1976;33(9):1062–6.
    • (1976) Arch Gen Psychiatry , vol.33 , Issue.9 , pp. 1062-1066
    • Himmelhoch, J.M.1
  • 4
    • 0023199581 scopus 로고
    • Diagnosis and treatment of mixed mania
    • PID: 3799848, COI: 1:STN:280:DyaL2s%2FpslKksA%3D%3D
    • Secunda SK et al. Diagnosis and treatment of mixed mania. Am J Psychiatry. 1987;144(1):96–8.
    • (1987) Am J Psychiatry , vol.144 , Issue.1 , pp. 96-98
    • Secunda, S.K.1
  • 5
    • 0026440116 scopus 로고
    • Clinical and research implications of the diagnosis of dysphoric or mixed mania or hypomania
    • PID: 1359799, COI: 1:STN:280:DyaK3s%2Fnt1Cqtw%3D%3D
    • McElroy SL et al. Clinical and research implications of the diagnosis of dysphoric or mixed mania or hypomania. Am J Psychiatry. 1992;149(12):1633–44.
    • (1992) Am J Psychiatry , vol.149 , Issue.12 , pp. 1633-1644
    • McElroy, S.L.1
  • 6
    • 0029024506 scopus 로고
    • Differences and similarities in mixed and pure mania
    • PID: 7648841, COI: 1:STN:280:DyaK2Mzns12ntg%3D%3D
    • McElroy SL et al. Differences and similarities in mixed and pure mania. Compr Psychiatry. 1995;36(3):187–94.
    • (1995) Compr Psychiatry , vol.36 , Issue.3 , pp. 187-194
    • McElroy, S.L.1
  • 7
    • 0031012799 scopus 로고    scopus 로고
    • Depression during mania. Treatment response to lithium or divalproex
    • PID: 9006398, COI: 1:STN:280:DyaK2s7lvFSmtQ%3D%3D
    • Swann AC et al. Depression during mania. Treatment response to lithium or divalproex. Arch Gen Psychiatry. 1997;54(1):37–42.
    • (1997) Arch Gen Psychiatry , vol.54 , Issue.1 , pp. 37-42
    • Swann, A.C.1
  • 8
    • 34047244414 scopus 로고    scopus 로고
    • Manic symptoms and impulsivity during bipolar depressive episodes
    • PID: 17430294
    • Swann AC et al. Manic symptoms and impulsivity during bipolar depressive episodes. Bipolar Disord. 2007;9(3):206–12.
    • (2007) Bipolar Disord , vol.9 , Issue.3 , pp. 206-212
    • Swann, A.C.1
  • 9
    • 0025736298 scopus 로고
    • The manic-depressive mixed state: familial, temperamental and psychopathologic characteristics in 108 female inpatients
    • PID: 1828997
    • Dell'Osso L et al. The manic-depressive mixed state: familial, temperamental and psychopathologic characteristics in 108 female inpatients. Eur Arch Psychiatry Clin Neurosci. 1991;240(4–5):234–9.
    • (1991) Eur Arch Psychiatry Clin Neurosci , vol.240 , Issue.4-5 , pp. 234-239
    • Dell'Osso, L.1
  • 10
    • 0030970636 scopus 로고    scopus 로고
    • Clinical subtypes of bipolar mixed states: validating a broader European definition in 143 cases
    • PID: 9186787, COI: 1:STN:280:DyaK2szjtVehug%3D%3D
    • Perugi G et al. Clinical subtypes of bipolar mixed states: validating a broader European definition in 143 cases. J Affect Disord. 1997;43(3):169–80.
    • (1997) J Affect Disord , vol.43 , Issue.3 , pp. 169-180
    • Perugi, G.1
  • 11
    • 0035722903 scopus 로고    scopus 로고
    • Clinical characterization of depressive mixed state in bipolar-I patients: Pisa-San Diego collaboration
    • PID: 11869757, COI: 1:STN:280:DC%2BD387jsVyqtQ%3D%3D
    • Perugi G et al. Clinical characterization of depressive mixed state in bipolar-I patients: Pisa-San Diego collaboration. J Affect Disord. 2001;67(1–3):105–14.
    • (2001) J Affect Disord , vol.67 , Issue.1-3 , pp. 105-114
    • Perugi, G.1
  • 12
    • 0032876532 scopus 로고    scopus 로고
    • Agitated depression as a mixed state and the problem of melancholia
    • PID: 10550855, COI: 1:STN:280:DC%2BD3c%2FhvVGiug%3D%3D
    • Koukopoulos A. Agitated depression as a mixed state and the problem of melancholia. Psychiatr Clin North Am. 1999;22(3):547–64.
    • (1999) Psychiatr Clin North Am , vol.22 , Issue.3 , pp. 547-564
    • Koukopoulos, A.1
  • 13
    • 33846273492 scopus 로고    scopus 로고
    • Melancholia agitata and mixed depression
    • PID: 17280571
    • Koukopoulos A et al. Melancholia agitata and mixed depression. Acta Psychiatr Scand Suppl. 2007;433:50–7.
    • (2007) Acta Psychiatr Scand Suppl , vol.433 , pp. 50-57
    • Koukopoulos, A.1
  • 14
    • 0035721419 scopus 로고    scopus 로고
    • Delineating bipolar II mixed states in the Ravenna-San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes
    • PID: 11869758, COI: 1:STN:280:DC%2BD387jsVyqug%3D%3D
    • Benazzi F, Akiskal HS. Delineating bipolar II mixed states in the Ravenna-San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes. J Affect Disord. 2001;67(1–3):115–22.
    • (2001) J Affect Disord , vol.67 , Issue.1-3 , pp. 115-122
    • Benazzi, F.1    Akiskal, H.S.2
  • 15
    • 0032171098 scopus 로고    scopus 로고
    • Gender, temperament, and the clinical picture in dysphoric mixed mania: findings from a French national study (EPIMAN)
    • PID: 9858077, COI: 1:STN:280:DyaK1M%2FntlOrug%3D%3D
    • Akiskal HS et al. Gender, temperament, and the clinical picture in dysphoric mixed mania: findings from a French national study (EPIMAN). J Affect Disord. 1998;50(2–3):175–86.
    • (1998) J Affect Disord , vol.50 , Issue.2-3 , pp. 175-186
    • Akiskal, H.S.1
  • 16
    • 0029586462 scopus 로고
    • Dysphoric mania and mixed states
    • PID: 8582313
    • Bourgeois M, Verdoux H, Mainard CH. Dysphoric mania and mixed states. Encephale. 1995;21(Spec No 6):21–32.
    • (1995) Encephale , vol.21 , Issue.Spec No 6 , pp. 21-32
    • Bourgeois, M.1    Verdoux, H.2    Mainard, C.H.3
  • 17
    • 0022486615 scopus 로고
    • Lithium treatment of mania: clinical characteristics, specificity of symptom change, and outcome
    • PID: 3725997, COI: 1:STN:280:DyaL283mtVersg%3D%3D
    • Swann AC et al. Lithium treatment of mania: clinical characteristics, specificity of symptom change, and outcome. Psychiatry Res. 1986;18(2):127–41.
    • (1986) Psychiatry Res , vol.18 , Issue.2 , pp. 127-141
    • Swann, A.C.1
  • 18
    • 0034894021 scopus 로고    scopus 로고
    • Subtypes of mania determined by grade of membership analysis
    • PID: 11522465, COI: 1:STN:280:DC%2BD3MvnvFCjsQ%3D%3D
    • Cassidy F, Pieper CF, Carroll BJ. Subtypes of mania determined by grade of membership analysis. Neuropsychopharmacology. 2001;25(3):373–83.
    • (2001) Neuropsychopharmacology , vol.25 , Issue.3 , pp. 373-383
    • Cassidy, F.1    Pieper, C.F.2    Carroll, B.J.3
  • 19
    • 4944237470 scopus 로고    scopus 로고
    • Validating Kraepelin’s two types of depressive mixed states: “depression with flight of ideas” and “excited depression
    • PID: 15179670
    • Akiskal HS, Benazzi F. Validating Kraepelin’s two types of depressive mixed states: “depression with flight of ideas” and “excited depression”. World J Biol Psychiatry. 2004;5(2):107–13.
    • (2004) World J Biol Psychiatry , vol.5 , Issue.2 , pp. 107-113
    • Akiskal, H.S.1    Benazzi, F.2
  • 21
    • 0035212674 scopus 로고    scopus 로고
    • Depressive mixed state: testing different definitions
    • PID: 11737800, COI: 1:STN:280:DC%2BD3MnptlWgsA%3D%3D
    • Benazzi F. Depressive mixed state: testing different definitions. Psychiatry Clin Neurosci. 2001;55(6):647–52.
    • (2001) Psychiatry Clin Neurosci , vol.55 , Issue.6 , pp. 647-652
    • Benazzi, F.1
  • 22
    • 84881327286 scopus 로고    scopus 로고
    • Reevaluation of patients with bipolar disorder on manic episode: improving the diagnosing of mixed episode
    • PID: 23896850
    • Kim KR et al. Reevaluation of patients with bipolar disorder on manic episode: improving the diagnosing of mixed episode. J Nerv Ment Dis. 2013;201(8):686–90.
    • (2013) J Nerv Ment Dis , vol.201 , Issue.8 , pp. 686-690
    • Kim, K.R.1
  • 23
    • 84882833688 scopus 로고    scopus 로고
    • DSM-5 mixed specifier for manic episodes: evaluating the effect of depressive features on severity and treatment outcome using asenapine clinical trial data
    • PID: 23712026, COI: 1:STN:280:DC%2BC3snntVKruw%3D%3D
    • McIntyre RS et al. DSM-5 mixed specifier for manic episodes: evaluating the effect of depressive features on severity and treatment outcome using asenapine clinical trial data. J Affect Disord. 2013;150(2):378–83.
    • (2013) J Affect Disord , vol.150 , Issue.2 , pp. 378-383
    • McIntyre, R.S.1
  • 24
    • 84872177031 scopus 로고    scopus 로고
    • Bipolar mixed states: an international society for bipolar disorders task force report of symptom structure, course of illness, and diagnosis
    • PID: 23223893, The article is a very comprehensive and updated review of the current litherature on the clinical characteristics of mixed states
    • Swann AC et al. Bipolar mixed states: an international society for bipolar disorders task force report of symptom structure, course of illness, and diagnosis. Am J Psychiatry. 2013;170(1):31–42. The article is a very comprehensive and updated review of the current litherature on the clinical characteristics of mixed states.
    • (2013) Am J Psychiatry , vol.170 , Issue.1 , pp. 31-42
    • Swann, A.C.1
  • 25
    • 0347683369 scopus 로고    scopus 로고
    • Mixed depressive features predict maniform switch during treatment of depression in bipolar I disorder
    • PID: 14706725
    • Bottlender R et al. Mixed depressive features predict maniform switch during treatment of depression in bipolar I disorder. J Affect Disord. 2004;78(2):149–52.
    • (2004) J Affect Disord , vol.78 , Issue.2 , pp. 149-152
    • Bottlender, R.1
  • 26
    • 84857356280 scopus 로고    scopus 로고
    • Mixed depression: a study of its phenomenology and relation to treatment response
    • PID: 22173265
    • Pae CU et al. Mixed depression: a study of its phenomenology and relation to treatment response. J Affect Disord. 2012;136(3):1059–61.
    • (2012) J Affect Disord , vol.136 , Issue.3 , pp. 1059-1061
    • Pae, C.U.1
  • 27
    • 60349113309 scopus 로고    scopus 로고
    • Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD
    • PID: 19122008
    • Goldberg JF et al. Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry. 2009;166(2):173–81.
    • (2009) Am J Psychiatry , vol.166 , Issue.2 , pp. 173-181
    • Goldberg, J.F.1
  • 28
    • 33646343938 scopus 로고    scopus 로고
    • The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum
    • PID: 16488021
    • Akiskal HS, Benazzi F. The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum. J Affect Disord. 2006;92(1):45–54.
    • (2006) J Affect Disord , vol.92 , Issue.1 , pp. 45-54
    • Akiskal, H.S.1    Benazzi, F.2
  • 29
    • 13544265389 scopus 로고    scopus 로고
    • Irritable psychomotor elation in depressed inpatients: a factor validation of mixed depression
    • PID: 15708416, COI: 1:STN:280:DC%2BD2M%2FnvFamsw%3D%3D
    • Sato T et al. Irritable psychomotor elation in depressed inpatients: a factor validation of mixed depression. J Affect Disord. 2005;84(2–3):187–96.
    • (2005) J Affect Disord , vol.84 , Issue.2-3 , pp. 187-196
    • Sato, T.1
  • 30
    • 0035719981 scopus 로고    scopus 로고
    • Structure of mania: depressive, irritable, and psychotic clusters with different retrospectively-assessed course patterns of illness in randomized clinical trial participants
    • PID: 11869759, COI: 1:STN:280:DC%2BD387jsVyquw%3D%3D
    • Swann AC et al. Structure of mania: depressive, irritable, and psychotic clusters with different retrospectively-assessed course patterns of illness in randomized clinical trial participants. J Affect Disord. 2001;67(1–3):123–32.
    • (2001) J Affect Disord , vol.67 , Issue.1-3 , pp. 123-132
    • Swann, A.C.1
  • 31
    • 1642465487 scopus 로고    scopus 로고
    • Toward a validation of a new definition of agitated depression as a bipolar mixed state (mixed depression)
    • PID: 15051107, COI: 1:STN:280:DC%2BD2c7lsleluw%3D%3D
    • Benazzi F, Koukopoulos A, Akiskal HS. Toward a validation of a new definition of agitated depression as a bipolar mixed state (mixed depression). Eur Psychiatry. 2004;19(2):85–90.
    • (2004) Eur Psychiatry , vol.19 , Issue.2 , pp. 85-90
    • Benazzi, F.1    Koukopoulos, A.2    Akiskal, H.S.3
  • 32
    • 36749019649 scopus 로고    scopus 로고
    • Phenomenology of mixed states: a principal component analysis study
    • PID: 18076542, COI: 1:STN:280:DC%2BD2sjjvFyrtg%3D%3D
    • Bertschy G et al. Phenomenology of mixed states: a principal component analysis study. Bipolar Disord. 2007;9(8):907–12.
    • (2007) Bipolar Disord , vol.9 , Issue.8 , pp. 907-912
    • Bertschy, G.1
  • 33
    • 70350474522 scopus 로고    scopus 로고
    • Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features
    • PID: 19812754
    • Swann AC et al. Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features. World Psychiatry. 2009;8(3):166–72.
    • (2009) World Psychiatry , vol.8 , Issue.3 , pp. 166-172
    • Swann, A.C.1
  • 34
    • 84889881154 scopus 로고    scopus 로고
    • Bipolar mixed states: still mixed up?
    • PID: 24270474
    • Castle DJ. Bipolar mixed states: still mixed up? Curr Opin Psychiatry. 2014;27(1):38–42.
    • (2014) Curr Opin Psychiatry , vol.27 , Issue.1 , pp. 38-42
    • Castle, D.J.1
  • 35
    • 80051670514 scopus 로고    scopus 로고
    • Mania and depression. Mixed, not stirred
    • PID: 21514674
    • Pacchiarotti I et al. Mania and depression. Mixed, not stirred. J Affect Disord. 2011;133(1–2):105–13.
    • (2011) J Affect Disord , vol.133 , Issue.1-2 , pp. 105-113
    • Pacchiarotti, I.1
  • 36
    • 84886725025 scopus 로고    scopus 로고
    • Clinical subtypes of severe bipolar mixed states
    • PID: 24074482
    • Perugi G et al. Clinical subtypes of severe bipolar mixed states. J Affect Disord. 2013;151(3):1076–82.
    • (2013) J Affect Disord , vol.151 , Issue.3 , pp. 1076-1082
    • Perugi, G.1
  • 37
    • 0027372089 scopus 로고
    • Depressive mania associated with nonresponse to antimanic agents
    • PID: 8104389, COI: 1:STN:280:DyaK3szpt12mtw%3D%3D
    • Dilsaver SC et al. Depressive mania associated with nonresponse to antimanic agents. Am J Psychiatry. 1993;150(10):1548–51.
    • (1993) Am J Psychiatry , vol.150 , Issue.10 , pp. 1548-1551
    • Dilsaver, S.C.1
  • 38
    • 0032170382 scopus 로고    scopus 로고
    • Bipolar I affective disorder: predictors of outcome after 15 years
    • PID: 9858070, COI: 1:STN:280:DyaK1M%2FntlOrsw%3D%3D
    • Coryell W et al. Bipolar I affective disorder: predictors of outcome after 15 years. J Affect Disord. 1998;50(2–3):109–16.
    • (1998) J Affect Disord , vol.50 , Issue.2-3 , pp. 109-116
    • Coryell, W.1
  • 39
    • 33751526972 scopus 로고    scopus 로고
    • Validating the bipolar spectrum in the French National EPIDEP Study: overview of the phenomenology and relative prevalence of its clinical prototypes
    • PID: 16824616
    • Akiskal HS et al. Validating the bipolar spectrum in the French National EPIDEP Study: overview of the phenomenology and relative prevalence of its clinical prototypes. J Affect Disord. 2006;96(3):197–205.
    • (2006) J Affect Disord , vol.96 , Issue.3 , pp. 197-205
    • Akiskal, H.S.1
  • 40
    • 47549113501 scopus 로고    scopus 로고
    • Differences in incidence of suicide attempts during phases of bipolar I and II disorders
    • PID: 18657243
    • Valtonen HM et al. Differences in incidence of suicide attempts during phases of bipolar I and II disorders. Bipolar Disord. 2008;10(5):588–96.
    • (2008) Bipolar Disord , vol.10 , Issue.5 , pp. 588-596
    • Valtonen, H.M.1
  • 41
    • 33746227775 scopus 로고    scopus 로고
    • Does the FDA proposed list of possible correlates of suicidality associated with antidepressants apply to an adult private practice population?
    • PID: 16766043
    • Akiskal HS, Benazzi F. Does the FDA proposed list of possible correlates of suicidality associated with antidepressants apply to an adult private practice population? J Affect Disord. 2006;94(1–3):105–10.
    • (2006) J Affect Disord , vol.94 , Issue.1-3 , pp. 105-110
    • Akiskal, H.S.1    Benazzi, F.2
  • 42
    • 33644994494 scopus 로고    scopus 로고
    • The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention
    • PID: 16458364
    • Balazs J et al. The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention. J Affect Disord. 2006;91(2–3):133–8.
    • (2006) J Affect Disord , vol.91 , Issue.2-3 , pp. 133-138
    • Balazs, J.1
  • 43
    • 70349882158 scopus 로고    scopus 로고
    • Suicidal ideation and suicide attempts in bipolar disorder type I: an update for the clinician
    • PID: 19787156
    • Abreu LN et al. Suicidal ideation and suicide attempts in bipolar disorder type I: an update for the clinician. Rev Bras Psiquiatr. 2009;31(3):271–80.
    • (2009) Rev Bras Psiquiatr , vol.31 , Issue.3 , pp. 271-280
    • Abreu, L.N.1
  • 44
    • 84893816379 scopus 로고    scopus 로고
    • A reevaluation of the possibility and characteristics in bipolar mania with mixed features: a retrospective chart review
    • PID: 24315032
    • Shim IH et al. A reevaluation of the possibility and characteristics in bipolar mania with mixed features: a retrospective chart review. Psychiatry Res. 2014;215(2):335–40.
    • (2014) Psychiatry Res , vol.215 , Issue.2 , pp. 335-340
    • Shim, I.H.1
  • 45
    • 34547179023 scopus 로고    scopus 로고
    • Epidemiology, diagnosis and management of mixed mania
    • PID: 17630815, COI: 1:CAS:528:DC%2BD2sXpvFCnt7Y%3D
    • Gonzalez-Pinto A et al. Epidemiology, diagnosis and management of mixed mania. CNS Drugs. 2007;21(8):611–26.
    • (2007) CNS Drugs , vol.21 , Issue.8 , pp. 611-626
    • Gonzalez-Pinto, A.1
  • 46
    • 80054999720 scopus 로고    scopus 로고
    • Depression symptom ratings in geriatric patients with bipolar mania
    • PID: 21360754
    • Sajatovic M et al. Depression symptom ratings in geriatric patients with bipolar mania. Int J Geriatr Psychiatry. 2011;26(11):1201–8.
    • (2011) Int J Geriatr Psychiatry , vol.26 , Issue.11 , pp. 1201-1208
    • Sajatovic, M.1
  • 47
    • 41649111361 scopus 로고    scopus 로고
    • Understanding the complexity of bipolar mixed episodes
    • PID: 18363450
    • McElroy SL. Understanding the complexity of bipolar mixed episodes. J Clin Psychiatry. 2008;69(2):e06.
    • (2008) J Clin Psychiatry , vol.69 , Issue.2 , pp. e06
    • McElroy, S.L.1
  • 48
    • 0026456894 scopus 로고
    • The distinctive mixed states of bipolar I, II, and III
    • PID: 1498979
    • Akiskal HS. The distinctive mixed states of bipolar I, II, and III. Clin Neuropharmacol. 1992;15(Suppl 1 Pt A):632A–3.
    • (1992) Clin Neuropharmacol , vol.15 , pp. 632-633
    • Akiskal, H.S.1
  • 49
    • 0032170813 scopus 로고    scopus 로고
    • Signs and symptoms of mania in pure and mixed episodes
    • PID: 9858078, COI: 1:STN:280:DyaK1M%2FntlOruw%3D%3D
    • Cassidy F et al. Signs and symptoms of mania in pure and mixed episodes. J Affect Disord. 1998;50(2–3):187–201.
    • (1998) J Affect Disord , vol.50 , Issue.2-3 , pp. 187-201
    • Cassidy, F.1
  • 50
    • 0027215333 scopus 로고
    • Specificity of mixed affective states: clinical comparison of dysphoric mania and agitated depression
    • PID: 8354772, COI: 1:STN:280:DyaK3szlvFGqsw%3D%3D
    • Swann AC et al. Specificity of mixed affective states: clinical comparison of dysphoric mania and agitated depression. J Affect Disord. 1993;28(2):81–9.
    • (1993) J Affect Disord , vol.28 , Issue.2 , pp. 81-89
    • Swann, A.C.1
  • 51
    • 0034235338 scopus 로고    scopus 로고
    • Qualitative differences in manic symptoms during mixed versus pure mania
    • PID: 10929789, COI: 1:STN:280:DC%2BD3M%2FksFGrsw%3D%3D
    • Goldberg JF et al. Qualitative differences in manic symptoms during mixed versus pure mania. Compr Psychiatry. 2000;41(4):237–41.
    • (2000) Compr Psychiatry , vol.41 , Issue.4 , pp. 237-241
    • Goldberg, J.F.1
  • 52
    • 25844452005 scopus 로고    scopus 로고
    • Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon
    • PID: 16203954
    • Suppes T et al. Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon. Arch Gen Psychiatry. 2005;62(10):1089–96.
    • (2005) Arch Gen Psychiatry , vol.62 , Issue.10 , pp. 1089-1096
    • Suppes, T.1
  • 53
    • 0037219488 scopus 로고    scopus 로고
    • Family history validation of the bipolar nature of depressive mixed states
    • PID: 12507744
    • Akiskal HS, Benazzi F. Family history validation of the bipolar nature of depressive mixed states. J Affect Disord. 2003;73(1–2):113–22.
    • (2003) J Affect Disord , vol.73 , Issue.1-2 , pp. 113-122
    • Akiskal, H.S.1    Benazzi, F.2
  • 54
    • 73149116000 scopus 로고    scopus 로고
    • Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity
    • PID: 19996039
    • Zimmermann P et al. Heterogeneity of DSM-IV major depressive disorder as a consequence of subthreshold bipolarity. Arch Gen Psychiatry. 2009;66(12):1341–52.
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.12 , pp. 1341-1352
    • Zimmermann, P.1
  • 55
    • 15244358704 scopus 로고    scopus 로고
    • Agitated “unipolar”depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy
    • PID: 15780694
    • Akiskal HS et al. Agitated “unipolar”depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy. J Affect Disord. 2005;85(3):245–58.
    • (2005) J Affect Disord , vol.85 , Issue.3 , pp. 245-258
    • Akiskal, H.S.1
  • 56
    • 78651288679 scopus 로고    scopus 로고
    • Subthreshold hypomanic symptoms in progression from unipolar major depression to bipolar disorder
    • PID: 21078709
    • Fiedorowicz JG et al. Subthreshold hypomanic symptoms in progression from unipolar major depression to bipolar disorder. Am J Psychiatry. 2011;168(1):40–8.
    • (2011) Am J Psychiatry , vol.168 , Issue.1 , pp. 40-48
    • Fiedorowicz, J.G.1
  • 57
    • 84898834216 scopus 로고    scopus 로고
    • Phenomenological subtypes of severe bipolar mixed states: a factor analytic study
    • PID: 24582325, The study is focused on the symptomatological presentation of severe mixed states. Sixty percent of the patients did not showed dominant manic or depressive features and cannot be easily described according to a combinatory model
    • Perugi G et al. Phenomenological subtypes of severe bipolar mixed states: a factor analytic study. Compr Psychiatry. 2014;55(4):799–806. The study is focused on the symptomatological presentation of severe mixed states. Sixty percent of the patients did not showed dominant manic or depressive features and cannot be easily described according to a combinatory model.
    • (2014) Compr Psychiatry , vol.55 , Issue.4 , pp. 799-806
    • Perugi, G.1
  • 58
    • 84890728080 scopus 로고    scopus 로고
    • Mixed states between schizophrenia and bipolar disorders
    • PID: 24359848
    • Azorin JM, Belzeaux R, Fakra E. Mixed states between schizophrenia and bipolar disorders. Encephale. 2013;39(3):S127–8.
    • (2013) Encephale , vol.39 , Issue.3 , pp. S127-S128
    • Azorin, J.M.1    Belzeaux, R.2    Fakra, E.3
  • 59
    • 0023215677 scopus 로고
    • Criteria for the “soft” bipolar spectrum: treatment implications
    • PID: 3602332, COI: 1:STN:280:DyaL2s3mtFOmtA%3D%3D
    • Akiskal HS, Mallya G. Criteria for the “soft” bipolar spectrum: treatment implications. Psychopharmacol Bull. 1987;23(1):68–73.
    • (1987) Psychopharmacol Bull , vol.23 , Issue.1 , pp. 68-73
    • Akiskal, H.S.1    Mallya, G.2
  • 60
    • 84889597306 scopus 로고    scopus 로고
    • Evidence-based definitions of bipolar-I and bipolar-II disorders among 5,635 patients with major depressive episodes in the Bridge Study: validity and comorbidity
    • Angst, J., et al., Evidence-based definitions of bipolar-I and bipolar-II disorders among 5,635 patients with major depressive episodes in the Bridge Study: validity and comorbidity. Eur Arch Psychiatry Clin Neurosci, 2013.
    • (2013) Eur Arch Psychiatry Clin Neurosci
    • Angst, J.1
  • 61
    • 84887942499 scopus 로고    scopus 로고
    • DSM-5 criteria for depression with mixed features: a farewell to mixed depression
    • PID: 23600771, The article review the available empirical evidence on the clinical presentation of mixed depression, suggesting that the non-evidence based definition of the DSM-5 “specifier” can be misleading and very restrictive
    • Koukopoulos A, Sani G. DSM-5 criteria for depression with mixed features: a farewell to mixed depression. Acta Psychiatr Scand. 2013. doi:10.1111/acps.12140. The article review the available empirical evidence on the clinical presentation of mixed depression, suggesting that the non-evidence based definition of the DSM-5 “specifier” can be misleading and very restrictive.
    • (2013) Acta Psychiatr Scand
    • Koukopoulos, A.1    Sani, G.2
  • 62
    • 15744400568 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression
    • PID: 15994719
    • Calabrese JR et al. A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression. Am J Psychiatry. 2005;162(7):1351–60.
    • (2005) Am J Psychiatry , vol.162 , Issue.7 , pp. 1351-1360
    • Calabrese, J.R.1
  • 63
    • 84873742563 scopus 로고    scopus 로고
    • Efficacy of quetiapine in patients with bipolar I and II depression: a multicenter, prospective, open-label, observational study
    • PID: 23431086, COI: 1:CAS:528:DC%2BC3sXjtl2rur0%3D
    • Jeong JH et al. Efficacy of quetiapine in patients with bipolar I and II depression: a multicenter, prospective, open-label, observational study. Neuropsychiatr Dis Treat. 2013;9:197–204.
    • (2013) Neuropsychiatr Dis Treat , vol.9 , pp. 197-204
    • Jeong, J.H.1
  • 64
    • 84872861182 scopus 로고    scopus 로고
    • Effect of asenapine on manic and depressive symptoms in bipolar I patients with mixed episodes: results from post hoc analyses
    • PID: 22868059, COI: 1:CAS:528:DC%2BC38XhtFGrtL3L
    • Azorin JM, Sapin C, Weiller E. Effect of asenapine on manic and depressive symptoms in bipolar I patients with mixed episodes: results from post hoc analyses. J Affect Disord. 2013;145(1):62–9.
    • (2013) J Affect Disord , vol.145 , Issue.1 , pp. 62-69
    • Azorin, J.M.1    Sapin, C.2    Weiller, E.3
  • 65
    • 84896456662 scopus 로고    scopus 로고
    • Asenapine treatment and health-related quality of life in patients experiencing bipolar I disorder with mixed episodes: post-hoc analyses of pivotal trials
    • PID: 24329543, COI: 1:CAS:528:DC%2BC2cXltFensrc%3D
    • Michalak EE, Guiraud-Diawara A, Sapin C. Asenapine treatment and health-related quality of life in patients experiencing bipolar I disorder with mixed episodes: post-hoc analyses of pivotal trials. Curr Med Res Opin. 2014;30(4):711–8.
    • (2014) Curr Med Res Opin , vol.30 , Issue.4 , pp. 711-718
    • Michalak, E.E.1    Guiraud-Diawara, A.2    Sapin, C.3
  • 66
    • 84894222651 scopus 로고    scopus 로고
    • Mixed state discrimination: a DSM problem that wont go away?
    • PID: 24655759
    • Malhi GS et al. Mixed state discrimination: a DSM problem that wont go away? J Affect Disord. 2014;158:8–10.
    • (2014) J Affect Disord , vol.158 , pp. 8-10
    • Malhi, G.S.1
  • 67
    • 0035719897 scopus 로고    scopus 로고
    • A prospective study of inter-episode consistency of manic and mixed subtypes of bipolar disorder
    • PID: 11869766, COI: 1:STN:280:DC%2BD387jsV2jtA%3D%3D
    • Cassidy F, Ahearn E, Carroll BJ. A prospective study of inter-episode consistency of manic and mixed subtypes of bipolar disorder. J Affect Disord. 2001;67(1–3):181–5.
    • (2001) J Affect Disord , vol.67 , Issue.1-3 , pp. 181-185
    • Cassidy, F.1    Ahearn, E.2    Carroll, B.J.3
  • 68
    • 4043149342 scopus 로고    scopus 로고
    • Evaluating the inter-episode stability of depressive mixed states
    • PID: 15306135
    • Sato T et al. Evaluating the inter-episode stability of depressive mixed states. J Affect Disord. 2004;81(2):103–13.
    • (2004) J Affect Disord , vol.81 , Issue.2 , pp. 103-113
    • Sato, T.1
  • 69
    • 0034208237 scopus 로고    scopus 로고
    • Clinical characteristics of familial and non-familial bipolar disorder
    • PID: 11252653, COI: 1:STN:280:DC%2BD3M3gs1GntQ%3D%3D
    • Moorhead S, Scott J. Clinical characteristics of familial and non-familial bipolar disorder. Bipolar Disord. 2000;2(2):136–9.
    • (2000) Bipolar Disord , vol.2 , Issue.2 , pp. 136-139
    • Moorhead, S.1    Scott, J.2
  • 70
    • 0037392988 scopus 로고    scopus 로고
    • Frequency of manic symptoms during a depressive episode and unipolar ‘depressive mixed state’ as bipolar spectrum
    • PID: 12662249, COI: 1:STN:280:DC%2BD3s7ks1Ojtg%3D%3D
    • Sato T et al. Frequency of manic symptoms during a depressive episode and unipolar ‘depressive mixed state’ as bipolar spectrum. Acta Psychiatr Scand. 2003;107(4):268–74.
    • (2003) Acta Psychiatr Scand , vol.107 , Issue.4 , pp. 268-274
    • Sato, T.1
  • 71
    • 77957957255 scopus 로고    scopus 로고
    • Major depressive disorder with subthreshold bipolarity in the National Comorbidity Survey Replication
    • PID: 20713498
    • Angst J et al. Major depressive disorder with subthreshold bipolarity in the National Comorbidity Survey Replication. Am J Psychiatry. 2010;167(10):1194–201.
    • (2010) Am J Psychiatry , vol.167 , Issue.10 , pp. 1194-1201
    • Angst, J.1
  • 72
    • 33745407633 scopus 로고    scopus 로고
    • Agitated “unipolar” major depression: prevalence, phenomenology, and outcome
    • PID: 16841620
    • Maj M et al. Agitated “unipolar” major depression: prevalence, phenomenology, and outcome. J Clin Psychiatry. 2006;67(5):712–9.
    • (2006) J Clin Psychiatry , vol.67 , Issue.5 , pp. 712-719
    • Maj, M.1
  • 73
    • 84858284419 scopus 로고    scopus 로고
    • Prevalence and clinical significance of subsyndromal manic symptoms, including irritability and psychomotor agitation, during bipolar major depressive episodes
    • PID: 22314261
    • Judd LL et al. Prevalence and clinical significance of subsyndromal manic symptoms, including irritability and psychomotor agitation, during bipolar major depressive episodes. J Affect Disord. 2012;138(3):440–8.
    • (2012) J Affect Disord , vol.138 , Issue.3 , pp. 440-448
    • Judd, L.L.1
  • 74
    • 17844403285 scopus 로고    scopus 로고
    • Mixed depressive states: nosologic and therapeutic issues
    • PID: 16194768
    • Koukopoulos A et al. Mixed depressive states: nosologic and therapeutic issues. Int Rev Psychiatry. 2005;17(1):21–37.
    • (2005) Int Rev Psychiatry , vol.17 , Issue.1 , pp. 21-37
    • Koukopoulos, A.1
  • 75
    • 0037219475 scopus 로고    scopus 로고
    • The role of cyclothymia in atypical depression: toward a data-based reconceptualization of the borderline-bipolar II connection
    • PID: 12507741
    • Perugi G et al. The role of cyclothymia in atypical depression: toward a data-based reconceptualization of the borderline-bipolar II connection. J Affect Disord. 2003;73(1–2):87–98.
    • (2003) J Affect Disord , vol.73 , Issue.1-2 , pp. 87-98
    • Perugi, G.1
  • 76
    • 33845630646 scopus 로고    scopus 로고
    • Challenging the unipolar-bipolar division: does mixed depression bridge the gap?
    • PID: 16978754
    • Benazzi F. Challenging the unipolar-bipolar division: does mixed depression bridge the gap? Prog Neuropsychopharmacol Biol Psychiatry. 2007;31(1):97–103.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , Issue.1 , pp. 97-103
    • Benazzi, F.1
  • 77
    • 33751547754 scopus 로고    scopus 로고
    • Clinical and psychometric characterization of depression in mixed mania: a report from the French National Cohort of 1090 manic patients
    • PID: 16427703, COI: 1:STN:280:DC%2BD28jgvVChtg%3D%3D
    • Hantouche EG et al. Clinical and psychometric characterization of depression in mixed mania: a report from the French National Cohort of 1090 manic patients. J Affect Disord. 2006;96(3):225–32.
    • (2006) J Affect Disord , vol.96 , Issue.3 , pp. 225-232
    • Hantouche, E.G.1
  • 78
    • 84939887857 scopus 로고    scopus 로고
    • T.C., Fordis J, Wisniewski S, Thase ME, Sachs GS, Antidepressant use during mixed states: naturalistic outcome data from the STEP-1000
    • Goldberg JF, T.C., Fordis J, Wisniewski S, Thase ME, Sachs GS, Antidepressant use during mixed states: naturalistic outcome data from the STEP-1000. Neuropsychopharmacology, 2004. 29.
    • (2004) Neuropsychopharmacology , pp. 29
    • Goldberg, J.F.1
  • 79
    • 22344433101 scopus 로고    scopus 로고
    • ‘Bipolarity’ in bipolar disorder: distribution of manic and depressive symptoms in a treated population
    • PID: 15994577
    • Bauer MS et al. ‘Bipolarity’ in bipolar disorder: distribution of manic and depressive symptoms in a treated population. Br J Psychiatry. 2005;187:87–8.
    • (2005) Br J Psychiatry , vol.187 , pp. 87-88
    • Bauer, M.S.1
  • 80
    • 0037219354 scopus 로고    scopus 로고
    • Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania
    • PID: 12507746
    • Angst J et al. Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania. J Affect Disord. 2003;73(1–2):133–46.
    • (2003) J Affect Disord , vol.73 , Issue.1-2 , pp. 133-146
    • Angst, J.1
  • 81
    • 0036944249 scopus 로고    scopus 로고
    • A prospective study of the offspring of bipolar parents responsive and nonresponsive to lithium treatment
    • PID: 12523878
    • Duffy A et al. A prospective study of the offspring of bipolar parents responsive and nonresponsive to lithium treatment. J Clin Psychiatry. 2002;63(12):1171–8.
    • (2002) J Clin Psychiatry , vol.63 , Issue.12 , pp. 1171-1178
    • Duffy, A.1
  • 82
    • 13444289396 scopus 로고    scopus 로고
    • Profiles of “manic” symptoms in bipolar I, bipolar II and major depressive disorders
    • PID: 15708413
    • Serretti A, Olgiati P. Profiles of “manic” symptoms in bipolar I, bipolar II and major depressive disorders. J Affect Disord. 2005;84(2–3):159–66.
    • (2005) J Affect Disord , vol.84 , Issue.2-3 , pp. 159-166
    • Serretti, A.1    Olgiati, P.2
  • 83
    • 13444284472 scopus 로고    scopus 로고
    • Dimensional psychopathology of depression: detection of an ‘activation’ dimension in unipolar depressed outpatients
    • PID: 15708410, COI: 1:STN:280:DC%2BD2M7ltVajsA%3D%3D
    • Biondi M et al. Dimensional psychopathology of depression: detection of an ‘activation’ dimension in unipolar depressed outpatients. J Affect Disord. 2005;84(2–3):133–9.
    • (2005) J Affect Disord , vol.84 , Issue.2-3 , pp. 133-139
    • Biondi, M.1
  • 84
    • 0036890164 scopus 로고    scopus 로고
    • Conceptual underpinnings and empirical support for the mood spectrum
    • PID: 12462856, v
    • Cassano GB et al. Conceptual underpinnings and empirical support for the mood spectrum. Psychiatr Clin North Am. 2002;25(4):699–712. v.
    • (2002) Psychiatr Clin North Am , vol.25 , Issue.4 , pp. 699-712
    • Cassano, G.B.1
  • 85
    • 84939918041 scopus 로고    scopus 로고
    • G., Angst J., Azorin, J., Bowden C.L., Mosolov, S., Reis, J., Vieta, E., Young, A.H., for the BRIDGE-II-Mix Study Group, Mixed Features in Patients with a Major Depressive Episode: the BRIDGE-II- MIX Study
    • Perugi, G., Angst J., Azorin, J., Bowden C.L., Mosolov, S., Reis, J., Vieta, E., Young, A.H., for the BRIDGE-II-Mix Study Group, Mixed Features in Patients with a Major Depressive Episode: the BRIDGE-II- MIX Study. J Clin Psych 2014.
    • (2014) J Clin Psych
  • 86
    • 33947116340 scopus 로고    scopus 로고
    • Bipolar disorder–focus on bipolar II disorder and mixed depression
    • PID: 17368155
    • Benazzi F. Bipolar disorder–focus on bipolar II disorder and mixed depression. Lancet. 2007;369(9565):935–45.
    • (2007) Lancet , vol.369 , Issue.9565 , pp. 935-945
    • Benazzi, F.1
  • 87
    • 84875222623 scopus 로고    scopus 로고
    • Subthreshold bipolar disorder in a U.S. national representative sample: prevalence, correlates and perspectives for psychiatric nosography
    • PID: 23040874
    • Hoertel N et al. Subthreshold bipolar disorder in a U.S. national representative sample: prevalence, correlates and perspectives for psychiatric nosography. J Affect Disord. 2013;146(3):338–47.
    • (2013) J Affect Disord , vol.146 , Issue.3 , pp. 338-347
    • Hoertel, N.1
  • 88
    • 33846416950 scopus 로고    scopus 로고
    • Is there a continuity between bipolar and depressive disorders?
    • PID: 17230047
    • Benazzi F. Is there a continuity between bipolar and depressive disorders? Psychother Psychosom. 2007;76(2):70–6.
    • (2007) Psychother Psychosom , vol.76 , Issue.2 , pp. 70-76
    • Benazzi, F.1
  • 89
    • 33745271042 scopus 로고    scopus 로고
    • A continuity between bipolar II depression and major depressive disorder?
    • PID: 16682104
    • Benazzi F. A continuity between bipolar II depression and major depressive disorder? Prog Neuropsychopharmacol Biol Psychiatry. 2006;30(6):1043–50.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , Issue.6 , pp. 1043-1050
    • Benazzi, F.1
  • 90
    • 0033663669 scopus 로고    scopus 로고
    • Attempted suicide and alcoholism in bipolar disorder: clinical and familial relationships
    • PID: 11097977, COI: 1:STN:280:DC%2BD3M%2Fps1OqtA%3D%3D
    • Potash JB et al. Attempted suicide and alcoholism in bipolar disorder: clinical and familial relationships. Am J Psychiatry. 2000;157(12):2048–50.
    • (2000) Am J Psychiatry , vol.157 , Issue.12 , pp. 2048-2050
    • Potash, J.B.1
  • 91
    • 16444375349 scopus 로고    scopus 로고
    • Bipolar disorder with comorbid cluster B personality disorder features: impact on suicidality
    • PID: 15766300
    • Garno JL et al. Bipolar disorder with comorbid cluster B personality disorder features: impact on suicidality. J Clin Psychiatry. 2005;66(3):339–45.
    • (2005) J Clin Psychiatry , vol.66 , Issue.3 , pp. 339-345
    • Garno, J.L.1
  • 92
    • 38049138683 scopus 로고    scopus 로고
    • The specific burden of comorbid anxiety disorders and of substance use disorders in bipolar I disorder
    • PID: 18199243
    • Goldstein BI, Levitt AJ. The specific burden of comorbid anxiety disorders and of substance use disorders in bipolar I disorder. Bipolar Disord. 2008;10(1):67–78.
    • (2008) Bipolar Disord , vol.10 , Issue.1 , pp. 67-78
    • Goldstein, B.I.1    Levitt, A.J.2
  • 93
    • 0034779749 scopus 로고    scopus 로고
    • Clinical correlates of psychiatric comorbidity in bipolar I patients
    • PID: 11903208, COI: 1:STN:280:DC%2BD387nsFaiuw%3D%3D
    • Vieta E et al. Clinical correlates of psychiatric comorbidity in bipolar I patients. Bipolar Disord. 2001;3(5):253–8.
    • (2001) Bipolar Disord , vol.3 , Issue.5 , pp. 253-258
    • Vieta, E.1
  • 94
    • 60349107434 scopus 로고    scopus 로고
    • Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression
    • PID: 19015231
    • Frye MA et al. Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression. Am J Psychiatry. 2009;166(2):164–72.
    • (2009) Am J Psychiatry , vol.166 , Issue.2 , pp. 164-172
    • Frye, M.A.1
  • 95
    • 34648827438 scopus 로고    scopus 로고
    • Adjunctive antidepressant use and symptomatic recovery among bipolar depressed patients with concomitant manic symptoms: findings from the STEP-BD
    • PID: 17728419
    • Goldberg JF et al. Adjunctive antidepressant use and symptomatic recovery among bipolar depressed patients with concomitant manic symptoms: findings from the STEP-BD. Am J Psychiatry. 2007;164(9):1348–55.
    • (2007) Am J Psychiatry , vol.164 , Issue.9 , pp. 1348-1355
    • Goldberg, J.F.1
  • 96
    • 84898602154 scopus 로고    scopus 로고
    • The challenge of treatment in bipolar depression: evidence from clinical guidelines, treatment recommendations and complex treatment situations
    • PID: 24549861, COI: 1:STN:280:DC%2BC2cvmtFWnug%3D%3D
    • Kohler S, Gaus S, Bschor T. The challenge of treatment in bipolar depression: evidence from clinical guidelines, treatment recommendations and complex treatment situations. Pharmacopsychiatry. 2014;47(2):53–9.
    • (2014) Pharmacopsychiatry , vol.47 , Issue.2 , pp. 53-59
    • Kohler, S.1    Gaus, S.2    Bschor, T.3
  • 97
    • 84890670668 scopus 로고    scopus 로고
    • Treatment of depressive mixed states
    • PID: 24359858
    • Dubois M et al. Treatment of depressive mixed states. Encephale. 2013;39(3):S179–84.
    • (2013) Encephale , vol.39 , Issue.3 , pp. S179-S184
    • Dubois, M.1
  • 98
    • 84939896730 scopus 로고    scopus 로고
    • ProposedDSM-mixedfeaturesareassociatedwithgreaterlikelihoodofremissioninout-patientswithmajordepressivedisorder.PsycholMed, The study focus on a post hoc analysis, comparing the outcome of major depressive patients with and without mixed features treated with antidepressants, Counterintuitively the Authors found a better outcome in patients with mixed features then in those without:
    • Perlis, R.H., C. Cusin, and M. Fava, Proposed DSM-5 mixed features are associated with greater likelihood of remission in out-patients with major depressive disorder. Psychol Med, 2012:1-7. The study focus on a post hoc analysis, comparing the outcome of major depressive patients with and without mixed features treated with antidepressants. Counterintuitively the Authors found a better outcome in patients with mixed features then in those without.
    • (2012) 1-7
    • Perlis, R.H.1    Cusin, C.2    Fava, M.3
  • 99
    • 84887436090 scopus 로고    scopus 로고
    • The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders
    • PID: 24030475, The article is a very comprehensive and updated review of the empirical evidence available on the controverse issue of the use of antidepressants in bipolar disorder
    • Pacchiarotti I et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013;170(11):1249–62. The article is a very comprehensive and updated review of the empirical evidence available on the controverse issue of the use of antidepressants in bipolar disorder.
    • (2013) Am J Psychiatry , vol.170 , Issue.11 , pp. 1249-1262
    • Pacchiarotti, I.1
  • 100
    • 84858298019 scopus 로고    scopus 로고
    • Rethinking the classification of mixed affective episodes in ICD-11
    • PID: 22284015, The article discuss the definition and the diagnostic role of mixed states. The authors conclude that a diagnostic category should be preferred to a specifier
    • Ostergaard SD et al. Rethinking the classification of mixed affective episodes in ICD-11. J Affect Disord. 2012;138(1-2):170–2. The article discuss the definition and the diagnostic role of mixed states. The authors conclude that a diagnostic category should be preferred to a specifier.
    • (2012) J Affect Disord , vol.138 , Issue.1-2 , pp. 170-172
    • Ostergaard, S.D.1
  • 101
    • 0026504054 scopus 로고
    • Mixed depressive syndrome
    • PID: 1600899
    • Koukopoulos A et al. Mixed depressive syndrome. Encephale. 1992;18(Spec No 1):19–21.
    • (1992) Encephale , vol.18 , Issue.Spec No 1 , pp. 19-21
    • Koukopoulos, A.1
  • 102
    • 84939918042 scopus 로고    scopus 로고
    • Electroconvulsive therapy (ECT) in 197 patients with severe, drug-resistant bipolar mixed state: treatment outcome and predictors of response
    • Medda, P., Toni, C., Giorgi Mariani, M., De Simone, L., Mauri, M., Perugi, G., Electroconvulsive therapy (ECT) in 197 patients with severe, drug-resistant bipolar mixed state: treatment outcome and predictors of response. J Clin Psych. 2014.
    • (2014) J Clin Psych
    • Medda, P.1    Toni, C.2    Giorgi Mariani, M.3    De Simone, L.4    Mauri, M.5    Perugi, G.6


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